Charcot-Leyden crystals: Pathology and diagnostic utility

Ear, Nose and Throat Journal

Volumn 83, Issue 7, 2004, Pages 489-490

  Pantanowitz, Liron ^a,b   Balogh, Karoly ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOPHOSPHOLIPASE;

ALLERGIC RHINITIS; ARTICLE; CHARCOT LEYDEN CRYSTAL; CRYSTAL; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE MARKER; EOSINOPHIL; EOSINOPHILIA; MORPHOLOGY; NOSE; PARANASAL SINUS; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT DISEASE; UPPER RESPIRATORY TRACT;

EID: 3342915503     PISSN: 01455613     EISSN: None     Source Type: Journal    
DOI: 10.1177/014556130408300717     Document Type: Article

References (25)

1. Stoop AE, van der Heijden HA, Biewenga J, van der Baan S. Eosinophils in nasal polyps and nasal mucosa: An immunohistochemical study. J Allergy Clin Immunol 1993;91:616-22.
2. Vaheri E. Nasal allergy with special reference to eosinophilia and histopathology. Acta Allergol 1956;10:203-11.
3. Stoop AE, van der Heijden HA, Biewenga J, van der Baan S. Lymphocytes and nonlymphoid cells in human nasal polyps. J Allergy Clin Immunol 1991;87:470-5.
4. Weller PF. The immunobiology of eosinophils. New Engl J Med 1991;324:1110-18.
5. Feather IH, Wilson SJ. Eosinophils in rhinitis. In: Busse WW, Holgate ST, eds. Asthma and Rhinitis. Boston: Blackwell Scientific Publications, 1995:347-63.
6. Leonidas DD, Elbert BL, Zhou Z, et al. Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure 1995;3:1379-93.
7. Charcot JM, Robin C. Observation de leucocythémie. Mem Soc Biol (Paris) 1853;5:44-50.
8. Leyden E. Zur Kenntriss des Asthma bronchiale. Virchows Arch A 1872;54:324-44.
9. Archer GT, Blackwood A. Formation of Charcot-Leyden crystals in human eosinophils and basophils and study of the composition of isolated crystals. J Exp Med 1965;122:173-80.
10. Carson HJ, Buschmann RJ, Weisz-Carrington P, Choi YS. Identification of Charcot-Leyden crystals by electron microscopy. Ultrastruct Pathol 1992;16:403-11.
11. Welsh RA. The genesis of the Charcot-Leyden crystal in the eosinophilic leukocyte of man. Am J Pathol 1959;35:1091-7.
12. Dvorak AM, Letourneau L, Login GR, et al. Ultrastructural localization of the Charcot-Leyden crystal protein (lysophospholipase) to a distinct crystalloid-free granule population in mature human eosinophils. Blood 1988;72:150-8.
13. Weller PF, Dvorak AM. Human eosinophils: Development, maturation, and functional morphology. In: Busse WW, Holgate ST, eds. Asthma and Rhinitis. Boston: Blackwell Scientific Publications, 1995:255-74.
14. Gleich GJ. Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 2000;105:651-63.
15. Weller PF, Goetzl EJ, Austen KF. Identification of human eosinophil lysophospholipase as the constituent of Charcot-Leyden crystals. Proc Natl Acad Sci 1980;77:7440-3.
16. Weller PF, Bach D, Austen KF. Human eosinophil lysophospholipase: The sole protein component of Charcot-Leyden crystals. J Immunol 1982;128:1346-9.
17. Harlin SL, Ansel DG, Lane SR, et al. A clinical and pathologic study of chronic sinusitis: The role of the eosinophil. J Allergy Clin Immunol 1988;81:867-75.
18. Jordana M, Dolovich J, Ohno I, et al. Nasal polyposis: A model for chronic inflammation. In: Busse WW, Holgate ST, eds. Asthma and Rhinitis. Boston: Blackwell Scientific Publications, 1995;156-64.
19. Kaufman HS, Rosen I, Shaposhnikov N, Wai M. Nasal eosinophilia. Ann Allergy 1982;49:270-1.
20. Miller RE, Paradise JL, Friday GA, et al. The nasal smear for eosinophils. Its value in children with seasonal allergic rhinitis. Am J Dis Child 1982;136:1009-11.
21. Arora VK, Singh N, Bhatia A. Charcot-Leyden crystals in fine needle aspiration cytology. Acta Cytol 1997;41:409-12.
22. Ayres WW, Starkey NM. Studies on Charcot-Leyden crystals. Blood 1950:254-66.
23. Lo JW, Fung CH. Autofluorescent Charcot-Leyden crystals. Arch Pathol Lab Med 1992;116:1101.
24. Jonathan D, Lund V, Milroy C. Allergic aspergillus sinusitis-An overlooked diagnosis? J Laryngol Otol 1989;103:1181-3.
25. Bent JP III, Kuhn FA. Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg 1994;111:580-8.