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Volumn 7, Issue 4, 2002, Pages 374-381

4a,5,9,10,11,12-hexahydro-6H-benzo[a]cyclohepta[hi]benzo-furan - Synthesis of unnatural galanthamine analogs

Author keywords

Galanthamine; Isopropylether deprotection; Phenol oxidation; Tandem cyclization

Indexed keywords

1 BROMO 4ALPHA 5,9,10,11,12 HEXAHYDRO 3 METHOXY 6 HYDROXY 6H BENZO[A]CYCLOHEPTA[HI]BENZOFURAN 10 CARBOXAMIDE; GALANTAMINE; UNCLASSIFIED DRUG;

EID: 3342885342     PISSN: 14203049     EISSN: None     Source Type: Journal    
DOI: 10.3390/70400374     Document Type: Article
Times cited : (12)

References (9)
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    • Enantioselective Total synthesis of (-)-galanthamine
    • For a recent compilation of galanthamine syntheses see: Trost, B. M.; Toste, F. D. Enantioselective Total Synthesis of (-)-Galanthamine. J. Am. Chem. Soc., 2000, 122, 11262-11263.
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    • Trost, B.M.1    Toste, F.D.2
  • 2
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    • Review of the acetylcholinesterase inhibitor galanthamine
    • For a review of the acetylcholinesterase activity see: Sramek, J. J.; Frackiewicz, E. J.; Cutler, N. R. Review of the acetylcholinesterase inhibitor galanthamine. Expert Opin. Invest. Drugs, 2000, 9, 2393-2402.
    • (2000) Expert Opin. Invest. Drugs , vol.9 , pp. 2393-2402
    • Sramek, J.J.1    Frackiewicz, E.J.2    Cutler, N.R.3
  • 3
    • 0014624138 scopus 로고
    • Studies on the syntheses of heterocyclic compounds. CCCXV. Modified total synthesis of (-)-galanthamine through phenol oxidation
    • Kametani, T.; Yamaki, K.; Yagi, H.; Fukumoto, K. Studies on the syntheses of heterocyclic compounds. CCCXV. Modified total synthesis of (-)-galanthamine through phenol oxidation. J. Chem. Soc. C, 1969, 2602-2605.
    • (1969) J. Chem. Soc. C , pp. 2602-2605
    • Kametani, T.1    Yamaki, K.2    Yagi, H.3    Fukumoto, K.4
  • 4
    • 37049065522 scopus 로고
    • Phenol oxidation and biosynthesis. V. Synthesis of galanthamine
    • Barton, D. H. R.; Kirby, G. W. Phenol oxidation and biosynthesis. V. Synthesis of galanthamine. J. Chem. Soc., 1962, 806-817.
    • (1962) J. Chem. Soc. , pp. 806-817
    • Barton, D.H.R.1    Kirby, G.W.2
  • 6
    • 0033479347 scopus 로고    scopus 로고
    • Development of a pilot scale process for the anti-Alzheimer drug (-)-galanthamine using large-scale phenolic oxidative coupling and crystallisation-induced chiral conversion
    • Kueenburg, B.; Czollner, L.; Froehlich, J.; Jordis, U.. Development of a pilot scale process for the anti-Alzheimer drug (-)-galanthamine using large-scale phenolic oxidative coupling and crystallisation-induced chiral conversion. Org. Process Res. Dev., 1999, 3, 425-431.
    • (1999) Org. Process Res. Dev. , vol.3 , pp. 425-431
    • Kueenburg, B.1    Czollner, L.2    Froehlich, J.3    Jordis, U.4
  • 7
    • 0035439163 scopus 로고    scopus 로고
    • 12H-[2]-benzothiepino[6,5a,5-bc]benzofuran: Synthesis of a sulfur-analog of galanthamine
    • Treu, M.; Jordis, U.; Mereiter, K. 12H-[2]-Benzothiepino[6,5a,5-bc] benzofuran: Synthesis of a Sulfur-Analog of Galanthamine. Heterocycles, 2001, 55, 1727-1735.
    • (2001) Heterocycles , vol.55 , pp. 1727-1735
    • Treu, M.1    Jordis, U.2    Mereiter, K.3
  • 8
    • 0037127780 scopus 로고    scopus 로고
    • Synthesis of (±)-6H-benzofuro[3a,3,2,ef][3]benzazepine, an unnatural analog of (-)-galanthamine
    • Poschalko, A.; Welzig, S.; Treu, M.; Nerdinger, S.; Mereiter, K.; Jordis, U. Synthesis of (±)-6H-Benzofuro[3a,3,2,ef][3]benzazepine, an Unnatural Analog of (-)-Galanthamine. Tetrahedron, 2002, 58, 1513-1518.
    • (2002) Tetrahedron , vol.58 , pp. 1513-1518
    • Poschalko, A.1    Welzig, S.2    Treu, M.3    Nerdinger, S.4    Mereiter, K.5    Jordis, U.6
  • 9
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    • Preparation process and effect of pyrimidine-5-carboxamides as cGMP phosphodiesterase inhibitors for circulatory and allergic diseases and sexual dysfunction remedies. WO 0127105, 2001
    • Miwa, T.; Yamamoto, M.; Doi, T.; Tarui, N. Preparation process and effect of pyrimidine-5-carboxamides as cGMP phosphodiesterase inhibitors for circulatory and allergic diseases and sexual dysfunction remedies. WO 0127105, 2001 [Chem. Abstr 2000, 134, 311217].
    • (2000) Chem. Abstr. , vol.134 , pp. 311217
    • Miwa, T.1    Yamamoto, M.2    Doi, T.3    Tarui, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.