Fumarate reductase: Structural and mechanistic insights from the catalytic reduction of 2-methylfumarate

FEBS Letters

Volumn 580, Issue 6, 2006, Pages 1677-1680

  Wardrope, Caroline ^a   Mowat, Christopher G ^a,b   Walkinshaw, Malcolm D ^b   Reid, Graeme A ^b   Chapman, Stephen K ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

2 Methylfumarate; 2 Methylsuccinate; Flavocytochrome c3; Fumarate reductase; Mesaconate

Indexed keywords

FUMARATE REDUCTASE; FUMARIC ACID DERIVATIVE; MESACONIC ACID ESTER; METHYLSUCCINIC ACID; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CATALYSIS; CIRCULAR DICHROISM; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME STRUCTURE; GRAM NEGATIVE BACTERIUM; NONHUMAN; PREDICTION; PRIORITY JOURNAL; REDUCTION; SHEWANELLA FRIGIDIMARINA; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

CATALYSIS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY; FUMARATES; MALEATES; OXIDATION-REDUCTION; PROTEIN CONFORMATION; SHEWANELLA; SUCCINATE DEHYDROGENASE; SUCCINATES;

NEGIBACTERIA; SHEWANELLA FRIGIDIMARINA;

EID: 33344472622     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.02.016     Document Type: Article

References (14)

1. T.M. Iverson, C. Luna-Chavez, G. Cecchini, and D.C. Rees Structure of the Escherichia coli fumarate reductase respiratory complex Science 284 1999 1961 1966
2. C.R.D. Lancaster, A. Kröger, M. Auer, and H. Michel Structure of fumarate reductase from Wolinella succinogenes at 2.2 Å resolution Nature 402 1999 377 385
3. P. Taylor, S.L. Pealing, G.A. Reid, S.K. Chapman, and M.D. Walkinshaw Structural and mechanistic mapping of a unique fumarate reductase Nat. Struct. Biol. 6 1999 1108 1112
4. 3 fumarate reductase Nat. Struct. Biol. 6 1999 1104 1107
5. D. Leys, A.S. Tsapin, K.H. Nealson, T.E. Meyer, M.A. Cusanovich, and J.J. Van Beeumen Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1 Nat. Struct. Biol. 6 1999 1113 1117
6. C.G. Mowat, R. Moysey, C.S. Miles, D. Leys, M.K. Doherty, P. Taylor, M.D. Walkinshaw, G.A. Reid, and S.K. Chapman Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase Biochemistry 40 2001 12292 12298
7. 3 from Shewanella putrefaciens NCIMB400 Biochemistry 34 1995 6153 6158
8. P. Macheroux S.K. Chapman G.A. Reid Flavoprotein Protocols: Methods in Molecular Biology vol. 131 1999 Humana Press Totowa, NJ 1 7
9. Z. Otwinowski, and W. Minor Processing of X-ray diffraction data collected in oscillation mode Methods Enzymol. 276 1997 307 326
10. A. Roussel, and C. Cambillau TURBO-FRODO, in Silicon Graphics Geometry Partners Directory 86 1991 Silicon Graphics Mountain View, CA
11. G.N. Murshudov, A.A. Vagin, and E.J. Dodson Refinement of macromolecular structures by the maximum-likelihood method Acta Crystallogr. D53 1997 240 255
12. 3 from Shewanella frigidimarina NCIMB400 Biochemistry 38 1999 3302 3309
13. R.M. Esnouf An extensively modified version of MolScript that includes greatly enhanced coloring capabilities J. Mol. Graph. 15 1997 132 134
14. E.A. Merritt, and M.E.P. Murphy Raster3D version 2.0: a program for photorealistic molecular graphics Acta Crystallogr. D50 1994 869 873