Evaluation of cytotoxic and mutagenic effects of Coriolus versicolor and Funalia trogii extracts on mammalian cells

Drug and Chemical Toxicology

Volumn 29, Issue 1, 2006, Pages 69-83

  Ünyayar, Ali ^a   Demirbilek, Murat ^b   Turkoglu, Melisa ^b   Celik, Ayla ^a   Mazmanci, Mehmet A ^a   Erkurt, Emrah A ^a   Ünyayar, Serpil ^a   Cekic, Özlem ^a   Atacag, Hatice ^a  

^a MERSIN UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Antitumor effect; Coriolus versicolor; Cytotoxicity; Fibroblast; Funalia trogii; HeLa

Indexed keywords

ANTINEOPLASTIC AGENT; CORIOLUS VERSICOLOR EXTRACT; FUNALIA TROGII EXTRACT; LACCASE; MITOMYCIN C; PEROXIDASE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; CORIOLUS VERSICOLOR; CYTOTOXICITY; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; FEMALE; FIBROBLAST CULTURE; FUNALIA TROGII; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE CULTURE; MALE; MAMMAL CELL; MEDICINAL PLANT; MITOSIS INDEX; MUSHROOM; MUTAGENESIS; NORMAL HUMAN; SISTER CHROMATID EXCHANGE;

ANIMALS; BASIDIOMYCOTA; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FIBROBLASTS; HELA CELLS; HUMANS; LEUKOCYTES, MONONUCLEAR; MITOTIC INDEX; MUTAGENICITY TESTS; MUTAGENS; PLANT EXTRACTS; PLANTS, MEDICINAL; SISTER CHROMATID EXCHANGE;

BASIDIOMYCOTA; FUNALIA; FUNALIA TROGII; FUNGI; MAMMALIA; TRAMETES VERSICOLOR;

EID: 33344465778     PISSN: 01480545     EISSN: None     Source Type: Journal    
DOI: 10.1080/01480540500408655     Document Type: Article

References (61)

1. Aebi, H. E., Bergmeyer, J., Grabl, M. (1983). Catalase. In: Methods of Enzymatic Analysis, 3rd ed. Weinheim: Verlag Chemie, pp. 273-286.
2. Ali, M. B., Hahn, E. J., Paek, K. Y. (2005). Effects of temperature on oxidative stress defense systems, lipid peroxidation and lipoxygenase activity in Phalaenopsis. Plant Physiol. Biochem. 43(3):213-223.
3. Aydemir, N., Çelikler, S., Bilaloglu, R. (2005). In vitro genotoxic effects of the anticancer drug gemcitabine in human lymphocytes. Mutat. Res. 582:35-41.
4. Bai, Z., Harvey, L. M., McNeil, B. (2003). Elevated temperature effects on the oxidant/antioxidant balance in submerged batch cultures of the filamentous fungus Aspergillus niger B1-D. Biotechnol. Bioeng. 83(7):772-779.
5. Beyer, W. F., Fridowich, I. (1987). Assaying for superoxide dismutase activity: Some large consequences of minor changes in conditions. Anal. Biochem. 161:559-566.
6. Bonnet, M., Camares, O., Veisseire, P. (2000). Effects of zinc and influence of Acremonium lolii on growth parameters, chlorophyll a fluorescence and antioxidant enzyme activities of ryegrass (Lolium perenne L.cv Apollo). J. Exp. Botany. 51:945-953.
7. Bor, M., Özdemir, F., Türkan, I. (2003). The effect of salt stress on lipid peroxidation and antioxidants in leaves of sugar beet Beta vulgaris L. and wild beet Beta maritime L. Plant Sci. 164:77-84.
8. Carlberg, I., Mannervik, B. (1985). Glutathion reductase. Methods Enzymol. 113:484-490.
9. Chang, J. B., Park, W. H., Choi, E. C., Kim, B. K. (1988). Studies on constituents of the higher fungi of Korea (LIV). Anticancer components of. Favolus alveolarius. Arch. Pharmacol. Res. 11:203-12.
10. Celik, A., Akbaş, E. (2005). Evaluation of sister chromatid exchange and chromosomal aberration frequencies in peripheral blood lymphocytes of gasoline station attendants. Ecotoxicol. Environ. Safety. 60:106-112.
11. Chow, L. W., Lo, C. S., Loo, W. T., Hu, X. C., Sham, J. S. (2003). Polysaccharide peptide mediates apoptosis by up-regulating p21 gene and down-regulating cyclin D1 gene. Am. J. Chin. Med. 31:1-9.
12. Chu, K. K. W., Ho, S. S. S., Chow, A. H. L. (2002). Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values. J. Clin. Pharmacol. 42:976-984.
13. Chung, K. S., Kim, S. S., Kim, H. S., Kim, K. Y., Han, M. W., Kim, K. H. (1993). Effect of Kp, an antitumor protein polysaccharide from mycelial culture of Phellinus linteus on the humoral immune response of tumor bearing ICR mice to sheep red blood cells. Arch. Pharmacol. Res. 16:336-338.
14. Cooper, V. A., Nicell, J. A. (1996). Removal of phenols from a foundry waste water using horseradish peroxidase. Water Res. 30:954-964.
15. Cui, J., Chisti, Y. (2003). Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production. Biotechnol. Adv. 21:109-122.
16. Dong, Y., Kwan, C. Y., Chen, Z. N., Yang, M. P. (1996). Antitumour effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor in vitro and in vivo studies. Res. Commun. Mol. Pathol. Pharmacol. 92:140-148.
17. Dong, Y., Yang, M. P., Kwan, C. Y. (1997). In vitro inhibition of proliferation of HL-60 cells by tetrandrine and Coriolous versicolor peptide derived from Chinese medicinal herbs. Life Sci. 60:135-140.
18. Everett, S. A., Swann, E., Naylor, M. A., Stratford, M. R. L., Patel, K. B., Tian, N., Newman, R. G., Borivoj Vojnovic, C. J., Sugano, N., Choji, Y., Hibino, Y., Yasumura, S., Maeda, H. (1985). Anti-carcinogenic action of an alcohol-insoluble fraction (LAP1) from culture medium of Lentinus edodes mycelia. Cancer Lett. 27:1-6.
19. Fujita, H., Ogawa, K., Ikuzawa, M., Muto, S., Matsuki, M., Nakajima, S. (1988). Effect of PSK, a protein-bound polysaccharide from Coriolus versicolor, on drug-metabolizing enzymes in sarcoma-180 bearing and normal mice. Int. J. Immunopharmacol. 10:445-450.
20. Fryatt, T., Pettersson, H. I., Gardipee, W. T., Bray, K. C., Green, S. J., Slawin, A. M. Z., Beall, H. D., Moody, C. J. (2004). Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1). Bioorg. Med. Chem. 12:1667-1687.
21. Gray, A. M., Flatt, P. R. (1998). Insulin-releasing and insulin-like activity of Agaricus campestris (mushroom). J. Endocrinol. 157:259-266.
22. Han, S. N., Wu, D., Leka, L.S., Meydani, S. N. (1996). Effect of mushroom (Coriolus versicolor) extract on the immune response of young and old mice. FASEB J. 10:3200.
23. Hiroi, T., Ericksson, K. E. (1976). Microbiological degradation of lignin. Part I. Influence of cellulose on the degradation of lignin by the white rot fungus Pleurotus ostreatus. Svensk Papperstidning. 79:157-161.
24. Holz, O., Scherar, G., Brodtmeier, S., Koops, F., Warnke, K., Krause, T., Austen, A., Angerer, J., Tricker, A. R., Adlkofer, F. et al. (1995). Determination of low level exposure to volatile aromatic hydrocarbons and genotoxic effects in workers at a styrene plant. Occup. Environ. Med. 52:420-428.
25. Hoerauf, K. H., Schrögendorfer, K. F., Wiesner, G., Gruber, M., Spacek, A., Kress, H. G., Rudiger, H. W. (1999). Sister chromatid exchange in human lymphocytes exposed to isoflurane and nitrous oxide in vitro. Br. J. Anaesth. 82:268-270.
26. Hsieh, T. C., Wu, J. M. (2001). Cell growth and gene modulatory activities of Yunzhi (Windsor Wunxi) from mushroom Trametes versicolor in androgen-dependent and androgen-insensitive human prostate cancer cells. Int. J. Oncol. 18:81-88.
27. Hsieh, T. C., Kunicki, J., Darzynkiewicz, Z., Wu, J. M. (2002). Effects of extracts of Coriolus versicolor (I'm-Yunity) on cell-cycle progression and expression of interleukins-1 beta,-6, and -8 in promyelocytic HL-60 leukemic cells and mitogenically stimulated and non-stimulated human lymphocytes. J. Altern. Complement. Med. 8:591-602.
28. Kidd, P. M. (2000). The use of mushroom glucans and proteoglycans in cancer treatment. Altern. Med. Rev. 5:4-27.
29. Kiho, T., Itahashi, S., Sakushima, M., Matsunaga, T., Usui, S., Ukai, S. (1997). Polysaccharide in fungi, XXXVIII. Anti-diabetic activity and structural features of galatomannan elaborated by Pestalotiopsis species. Biol. Pharma. Bull. 20:118-121.
30. Kim, B. K., Park, E. K. (1979). Studies on the constituents of the higher fungi of Korea 12. Anti-neoplastic components of Coriolus versicolor Fr, Pleurotus ostreatus (Fr) Kummer and Lentinus edodes (BERK) Singer. J. Nat. Prod. 42:684.
31. Kim, D. H., Yang, B. K., Jeong, S. C., Park, J. B., Cho, S. P., Das, S. (2001). Production of a hypoglycemic, extracellular polysaccharide from the submerged culture of the mushroom. Phellinus linteus. Biotechnol. Lett. 23:513-517.
32. Krause, T., Scholz, J., Boettcher, H., Wappler, K. C., Schutle am Esch, J. (2003). Sevoflurane anaesthesia does not induce the formation of sister chromatid exchanges in peripheral blood lymphocytes of children. Br. J. Anaesth. 90:233-235.
33. Kumar, T. R., Kumar, P., Nand Sharma, P., ve Bisht, S. S. (2002). Modulation of oxidative stress responsive enzymes by excess cobalt. Plant Sci. 162:381-388.
34. Lau, C. B. S., Ho, C. Y., Kim, C. F., Leung, K. N., Fung, K. P., Tse, T. F., Chan, H. H. L., Chow, M. S. S. (2004). Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis. Life Sci. 75:797-808.
35. Lamberti, L., Bigatti-Ponzetto, P., Ardito, G. (1983). Cell kinetics and sister chromatid exchange frequency in human lymphocytes. Mutat. Res. 120:193-199.
36. Li, X. Y., Wang, J. F., Zhu, P. P., Liu, L., Ge, J. B., Yang, S. X. (1990). Immune enhancement of a polysaccharides peptides isolated from. Coriolus versicolor. Acta Pharmacol. Sinica 11:542-545.
37. Liu, F., Ooi, V. E. C., Liu, W. K., Chang, S. T. (1996). Immunomodulation and antitumor activity of polysaccharide-protein complex from the culture filtrates of a local edible mushroom. Tricholoma lobayense. Gen. Pharmacol. 27:621-624.
38. Lopez-Nigro, M. M., Palermo, A. M., Mudry, M. D., Carballo, M. A. (2003). Cytogenetic evaluation of two nitroimidazole derivative. Toxicol. in vitro 17:35-40.
39. Mao, X. W., Gridley, D. S. (1998). Effects of extract of Coriolus versicolor and IL-2 against three tumor lines. FASEB J. 12:5149. [Part 2 Suppl. S].
40. Mayer, P., Drews, J. (1980). Effect of a protein-bound polysaccharide from Coriolus versicolor on immunological parameters and experimental infections in mice. Infection 8:13-21.
41. Menezes-Benavente, L., Karam Teixeira, F., Alvim Kamei, C. L., ve Margis-Pinheiro, M. (2004). Salt stress induces altered expression of genes encoding antioxidant enzymes in seedlings of an Brazilian indica rice (Oryza sativa L.). Plant Sci. 166:323-331.
42. Mittler, R. (2002). Oxidative stress, antioxidants and stress tolerance. Trends Plant Sci 7:405-410.
43. Moody, J., Wardman, P. (2002). Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release. Biochem. Pharmacol. 63:1629-1639.
44. Moorhead, P. S., Nowell, W. J., Mellman, D. M., Batlips, D., Hungerford, A. (1960). Chromsome preparations of leukocytes cultured from peripheral blood. Exp. Cell. Res. 20:613-616.
45. Muzino, T. (1995). Bioactive biomolecules of mushroom - food, function and medicinal effect of mushroom fungi. Food Rev. Int. 11:7-21.
46. Ng, T. B. (1998). A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Plyporaceae). Gen. Pharmacol. 30:1-4.
47. Ooi, V. E., Liu, F. (1999). A review of pharmacological activities of mushroom polysaccharides. Int. J. Med. Mushrooms 1:195-206.
48. Pery, P., Wolf, S. (1974). New Giemsa method for the differential staining of sister chromatids. Nature 251:156-158.
49. Sakagami, H., Aoki, T., Simpson, A., Tanuma, S. (1991). Induction of immunopotentiation activity by a protein-bound polysaccharide, PSK (review). Anticancer Res 11:993-999.
50. Shigeoka, S., Ishikawa, T., Tamoi, M., Miyagawa, Y., Takeda, T., Yabuta, Y., Yoshimura, K. (2002). Regulation and function of ascorbate peroxidase isoenzymes. J. Exp. Botany 53:1305-1319.
51. Song, C. H., Jeon, Y. J., Yang, B. K., Ra, K. S., Kim, H. I. (1998). Anti-complementary activity of endo-polymers produced from submerged mycelial culture of higher fungi with particular reference to Lentinus edodes. Biotechnol. Lett. 20:741-744.
52. Spanswick, V. S., Cummings, J., Ritchie, A. A., Smyth, J. F. (1998). Pharmacological determinants of the antitumour activity of Mitomycin C. Biochem. Pharmacol. 56:1497-1503.
53. Torres, E., IBustos-Jaimes, I., Borgne, S. (2003). Potential use of oxidative enzymes for the detoxification of organic pollutants. Appl. Catal. B Environ. 46:1-15.
54. Tucker, J. D., Preston, R. J. (1996). Chromosome aberration, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment. Mutat. Res. 365:147-159.
55. Ullah, M. A., Bedford, C. T., Evans, C. S. (2000). Reactions of pentachlorophenol with laccase from Coriolus Versicolor. Appl. Microbiol. Biotechnol. 53:230-234.
56. Ünyayar, A., Mazmanci, A. M., Atacag, H., Erkurt, A. E., Coral, G. (2005). A Drimaren Blue X3LR dye decolorizing enzyme from Funalia trogii: one step isolation and identification. Enzyme Microbial Technol. 36:10-16.
57. Wang, H. X., Liu, W. K., Ng, T. B., Ooi, V. E., Chang, S. T. (1995). Immunomodulatory and antitumor activities of a polysaccharide-peptide complex from a mycelial culture of Tricholoma sp., a local edible mushroom. Life Sci. 57:269-281.
58. Wang, H. X., Ng, T. B., Ooi, V. E. C., Liu, W. K., Chang, S. T. (1996a). A polysaccharide - peptide complex from cultured mycelia of the mushroom Tricholoma mongolicum with immunoenhancing and antitumor activities. Biochem. Cell Biol. 74:95-100.
59. Wang, H. X., Ng, T. B., Liu, W. K., Ooi, V. E., Chang, S. T. (1996b). Polysaccharide-peptide complexes from the cultured mycelia of the mushroom Coriolus versicolor and their culture medium activate mouse lymphocytes and macrophages. Int. J. Biochem. Cell Biol. 28:601-607.
60. Yang, Q. Y., Jong, S. C., Li, X. Y., Zhou, J. X., Chen, R. T., Xu, L. Z. (1992a). Antitumor and immunomodulating activities of the polysaccharide - peptide (PSP) of Coriolus versicolor. J. Immunol. Immunopharmacol. 12:29-34.
61. Yang, M. M. P., Chen, Z., Kwok, J. S. L. (1992b). The anti-tumor effect of a small polypeptide from Coriolus versicolor (SPCV). Am. J. Chin. Med. 20:221-232.