Diltiazem release from Eudragit NE40 coated pellets and effects of thermal treatment

Saudi Pharmaceutical Journal

Volumn 14, Issue 1, 2006, Pages 69-74

  Nisar Ur Rahman, ^a   Yuen, K H ^b   Wong, Jia Woei ^b  

^a THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

^b SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

Coating; Controlled release; Diltiazem pellets; Eudragit NE40D; Thermal treatment

Indexed keywords

BUFFER; CHLORIDE; DILTIAZEM; EUDRAGIT; EUDRAGIT NE40; UNCLASSIFIED DRUG;

ARTICLE; DRUG COATING; DRUG PELLET; DRUG RELEASE; DRUG SOLUBILITY; DRUG SOLUTION; FILM COATING; IONIC STRENGTH; PH; TEMPERATURE DEPENDENCE; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 33344464705     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. United State Pharmacopeia 24/National Formulary 2000.
2. Savage GV and Rhodes CT. The sustained release coating of solid dosage forms: A historical review. Drug Dev. Ind. Pharm. 1995; 21: 93-118.
3. Eudragit Data Sheet. Rohm Pharma, Darmstadt, Germany 1989.
4. Harris MR and Ghebre-Sellassie I. In Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms (J. W. McGinity, ed.), Marcel Dekker, New York and Basel. 1989, p.63.
5. rd ed. Royal society of Great Britian. 2002, p. 873.
6. Billa N, Yuen KH and Peh KK. Diclofenac release from Eudragit-containing matrices and effects of thermal treatment. Drug Dev. Ind. Pharm. 1998; 24: 45-50.
7. nd ed. Marcel Dekker, USA. 2002, p.2067-2080.
8. Nisar ur Rahman, Yuen KH, Wong JW and Nurzalina AK. Differential scanning calorimetry and surface morphology studies on coated pellets using aqueous dispersions. Pak. J. Pharm. Sci. 2005; 18 (2): 19-23.
9. Gilligan CA and Po LWA. Factors affecting drug release from a pellet system coated with an aqueous colloidal dispersion. Int. J. Pharm. 1991; 73: 51-68.
10. Wesseling M and Bodmeier R. Influence of plasticization time, curing conditions, storage time and core properties on the drug release from aquacoat-coated pellets. Pharm. Dev. Technol. 2001; 6: 325-331.
11. Yuen KH, Desmukh AA and Newton JM. Development and n-vitro evaluation of a multiparticulate sustained release theophylline formulation. Pharm. Res. 1993; 10: 588-592.
12. Amighi K, Timmermans J, Puigdevall J, Baltes E and Moes AJ. Peroral sustained release film coated pellets as a means to overcome physicochemical and biological drug related problems. 1. In-vitro development and evaluation. Drug Dev. Ind. Pharm. 1998; 24: 509-515.
13. Bodmeier R, Guo X, Sarabia RE and Skultety PF. The influence of buffer species and strength on diltiazem HCl release from beads coated with the aqueous cationic polymer dispersions, Eudragit RS, RL 30D. Pharm. Res. 1996; 13: 52-56.
14. McClelland GA, Sutton SC, Engle K, and Zentner GM. The solubility-modulated osmotic pump: In-vitro/In-vivo release of diltiazem hydrochloride. Pharm. Res. 1991; 8: 88-92.