Mutagenicity study of butachlor and its metabolites using Salmonella typhimurium

Journal of Microbiology, Immunology and Infection

Volumn 38, Issue 6, 2005, Pages 409-416

  Hsu, Kuei Yao ^a   Lin, Hwai Jeng ^b   Lin, Jen Kun ^c   Kuo, Wein Shung ^d   Ou, Yueh Hsing ^e  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d CHENG HSIN REHABILITATION MEDICAL CENTER   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Acetamides; Acetanilides; Butachlor; Mutagenicity tests; Salmonella typhimurium

Indexed keywords

BUTOCLOR; HERBICIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENIC ACTIVITY; CONTROLLED STUDY; CYTOTOXICITY; GAS CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; MOUSE; MUTAGENICITY; NONHUMAN; SALMONELLA TYPHIMURIUM; SYNTHESIS;

ACETANILIDES; ANIMALS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HERBICIDES; MALE; MICROSOMES, LIVER; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM;

EID: 33344459505     PISSN: 16841182     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Salcedo SS, Reges PL. The effect of granular herbicides (Weedone, Machete and Treflan-R) at different time of application, tiller production and yield of transplanted rice. Weed Science 1972;24:16-20.
2. Taiwan Agrochemical Industry Association. In: Domestic manufacturers production and sale of pesticides in 1995;1996. Taipei, Taiwan.
3. Lee WJ, Hoppin JA, Blair A, Lubin JH, Dosemeci M, Sandler DP, et al. Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study. Am J Epidemiol 2004;159:373-80.
4. Moriya M, Ohta T, Watanable K, Miyazawa T, Kato K, Shirasu Y. Further mutagenicity studies on pesticides in bacterial reversion assay systems. Mutat Res 1983;116:185-216.
5. Lin MF, Wu CL, Wang TC. Pesticide clastogenicity in Chinese hamster ovary cells. Mutat Res 1987;188:241-50.
6. Wang TC, Lee TC, Lin MF, Lin SY. Induction of sister-chromatid exchanges by pesticides in primary rat tracheal epithelial cells and Chinese hamster ovary cells. Mutat Res 1987;188:311-21.
7. Ou YH, Chung PC, Chang YC, Ngo FQ, Hsu KY, Chen FD. Butachlor, a suspected carcinogen, alters growth and transformation characteristics of mouse liver cells. Chem Res Toxicol 2000;13:1321-5.
8. Thake DC, Iatropoulos MJ, Hard GC, Hotz KJ, Wang CX, Williams GM, et al. A study of the mechanism of butachlor-associated gastric neoplasms in Spraque-Dawley rats. Exp Toxicol Pathol 1995;47:107-16.
9. Hard GC, Iatropoulos MJ, Thake DC, Wheeler D, Tatematsu M, Hagiwara A, et al. Identity and pathogenesis of stomach tumors in Spraque-Dawley rats associated with the dietary administration of butachlor. Exp Toxicol Pathol 1995;47:95-105.
10. Taiwan Agrochemical Industry Association. In: Domestic manufacturers production & sale of pesticides in 2001; 2002. Taipei, Taiwan.
11. Wang L. A survey and development trend of Chinese pesticide industry. Nongyao 1999;38:1-8.
12. Zheng H, Ye C. Adsorption and mobility of acetochlor and butachlor on soil. Bull Environ Contam Toxicol 2002;68:509-16.
13. Ou YH, Lin JK. Biotransformation of butachlor through mercapturic acid pathway in rat tissue homogenates. J Toxicol Env Heal 1992;35:19-28.
14. Coleman S, Linderman R, Hodgson E, Rose RL. Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes. Environ Health Persp 2000;108:1151-7.
15. Adams R, Johnson JR, Wilcox CF. A multiple-step sequence. In: Laboratory experiments in organic chemistry. New York: Macmillan Publishing Co., Inc.; 1982:293-302.
16. Feng PC, Wratten SJ. In vitro oxidation of 2,6-diethylaniline by rat liver microsomal enzymes. J Agric Food Chem 1987;35:491-6.
17. Kasai H, Nishimura S. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 1984;12:2137-45.
18. Feng PC, Ptanella JE. Identification of mercapturic acid pathway metabolites of alachlor formed by liver and kidney homogenates of rats, mice and monkeys. Pestic Biochem Physiol 1988;31:81-90.
19. Feng PC, Panatella JE. In vitro oxidation of alachlor by liver microsomal enzymes from rats, mice and monkeys. Pestic Biochem Physiol 1989;33:16-25.
20. Feng PC, Wilson AG, McClanahan RH, Panatella JE, Wratten SJ. Metabolism of alachlor by rat and mouse liver and nasal turbinate tissues. Drug Metab Dispos 1990;18:373.
21. Colborn T, vom Saal FS, Soto AM. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Persp 1993;101:378-84.
22. Bowerman WW, Best DA, Grubb TG, Sikarskie JG, Giesy JP. Assessment of environmental endocrine disruptors in bald eagles of the Great Lakes. Chemosphere 2000;41:1569-74.
23. Ohlson CG, Hardell L. Testicular cancer and occupational exposures with a focus on xenoestrogens in poly vinyl chloride plastics. Chemosphere 2000;40:1277-82.
24. Jongbloet PH, Roeleveld N, Groenewoud HMM. Where the boys aren't: dioxin and the sex ratio. Environ Health Persp 2002;110:1-3.
25. Burow ME, Tang Y, Collins-Burow BM, Krajewski S, Reed JC, McLachlan JA, et al. Effects of environmental estrogens on tumor necrosis factor α-mediated apoptosis in MCF-7 cells. Carcinogenesis 1999;20:2057-61.