Elevated tryptase levels are associated with greater bone density in a cohort of patients with mastocytosis

International Archives of Allergy and Immunology

Volumn 139, Issue 3, 2006, Pages 265-270

  Kushnir Sukhov, Nataliya M ^a   Brittain, Erica ^a   Reynolds, James C ^b   Akin, Cem ^a   Metcalfe, Dean D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Dual energy X ray absorptiometry; Mast cell; Mastocytosis; Tryptase; Z score

Indexed keywords

TRYPTASE;

ADULT; ANAMNESIS; ARTICLE; BONE DENSITY; CLINICAL ARTICLE; CLINICAL EXAMINATION; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DEMOGRAPHY; DISEASE SEVERITY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; GASTROESOPHAGEAL REFLUX; HUMAN; HYPOTENSION; LABORATORY TEST; MALE; MASTOCYTOSIS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

BONE DENSITY; COHORT STUDIES; DENSITOMETRY, X-RAY; FEMALE; FEMUR NECK; HUMANS; LUMBAR VERTEBRAE; MALE; MASTOCYTOSIS; MIDDLE AGED; RADIUS; SERINE ENDOPEPTIDASES; STATISTICS, NONPARAMETRIC; TRYPTASES;

EID: 33344458341     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091172     Document Type: Article

References (25)

1. Akin C, Metcalfe DD: Systemic mastocytosis. Annu Rev Med 2004;55:419-432.
2. Valent P, Horny H-P, Li C, Longley BJ, Metcalfe DD, Parwaresch RM, Bennett JM: Mastocytosis; in Jaffee SNLHE, Stein H, Varderman JW (eds): World Health Organization Classification of Tumours: Pathology and Genetics in Tumours of Haematopoietic and Lymphoid Tissues. Lyon, IARC Press, 2001, pp 291-302.
3. Akin C, Metcalfe DD: Surrogate markers of disease in mastocytosis. Int Arch Allergy Immunol 2002;127:133-136.
4. Weide R, Ehlenz K, Lorenz W, Walthers E, Klausmann M, Pfluger KH: Successful treatment of osteoporosis in systemic mastocytosis with interferon alpha-2b. Ann Hematol 1996; 72:41-43.
5. Lehmann T, Beyeler C, Lammle B, Hunziker T, Vock P, Olah AJ, Dahinden C, Gerber NJ: Severe osteoporosis due to systemic mast cell disease: successful treatment with interferon alpha-2B. Br J Rheumatol 1996;35:898-900.
6. Chines A, Pacifici R, Avioli LV, Teitelbaum SL, Korenblat PE: Systemic mastocytosis presenting as osteoporosis: a clinical and histomorphometric study. J Clin Endocrinol Metab 1991;72:140-144.
7. Floman Y, Amir G: Systemic mastocytosis presenting with severe spinal osteopenia and multiple compression fractures. J Spinal Disord 1991;4:369-373.
8. Arlington ER, Eisenberg B, Hartshorne MF, Vela S, Dorin RI: Nuclear medicine imaging of systemic mastocytosis. J Nucl Med 1989;30: 2046-2068.
9. Avila NA, Ling A, Metcalfe D, Worobec AS: Mastocytosis: magnetic resonance imaging patterns of marrow disease. Skeletal Radiol 1998;27:119-126.
10. Casadei R, De Cristofaro R, Ferruzzi A: Systemic mastocytosis with skeletal involvement. Chir Organi Mov 1991;76:277-295.
11. Lopez-Gomez M, Mediavilla Garcia J, Omar M, Sampalo Lainz A, Jimenez-Alonso J: Bone involvement in systemic mastocytosis: report of 3 cases. An Med Interna 1991;8:395-397.
12. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy: Osteoporosis prevention, diagnosis, and therapy. JAMA, 2001;285:785-795.
13. Delsignore JL, Dvoretsky PM, Hicks DG, O'Keefe RJ, Rosier RN: Mastocytosis presenting as a skeletal disorder. Iowa Orthop J 1996; 16:126-134.
14. Rafii M, Firooznia H, Golimbu C, Balthazar E: Pathologic fracture in systemic mastocytosis. Radiographic spectrum and review of the literature. Clin Orthop Relat Res 1983;180:260-267.
15. de Gennes C, Kuntz D, de Vernejoul MC: Bone mastocytosis. A report of nine cases with a bone histomorphometric study. Clin Orthop 1992;279:281-291.
16. Kanis JA: Diagnosis of osteoporosis and assessment of fracture risk. Lancet 2002;359: 1929-1936.
17. Kemink SA, Smals AG, Kloppenborg PW: Systemic mastocytosis as a cause of osteoporosis. Ned Tijdschr Geneeskd 1996;140:1277-1279.
18. Luciani F, Capront P: Vertebral osteoporosis manifesting systemic mastocytosis. J Belge Radiol 1992;75:87-89.
19. Lidor C, Frisch B, Gazit D, Gepstein R, Hallel T, Mekori YA: Osteoporosis as the sole presentation of bone marrow mastocytosis. J Bone Miner Res 1990;5:871-876.
20. Harvey JA, Anderson HC, Borek D, Morris D, Lukert BP: Osteoporosis associated with mastocytosis confined to bone: report of two cases. Bone 1989;10:237-241.
21. Johansson C, Roupe G, Lindstedt G, Mellstrom D: Bone density, bone markers and bone radiological features in mastocytosis. Age Ageing 1996;25:1-7.
22. Genant HK, Cooper C, Poor G, Reid I, Ehrlich G, Kanis J, Nordin BE, Barrett-Connor E, Black D, Bonjour JP, Dawson-Hughes B, Delmas PD, Dequeker J, Ragi Eis S, Gennari C, Johnell O, Johnston CC Jr, Lau EM, Liberman UA, Lindsay R, Martin TJ, Masri B, Mautalen CA, Meunier PJ, Khaltaev N, et al: Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int 1999;10:259-264.
23. Pineau CA, Urowitz MB, Fortin PJ, Ibanez D, Gladman DD: Osteoporosis in systemic lupus erythematosus: factors associated with referral for bone mineral density studies, prevalence of osteoporosis and factors associated with reduced bone density. Lupus 2004;13:436-441.
24. Siffiledeen JS, Fedorak RN, Siminoski K, Jen H, Vaudan E, Abraham N, Seinhart H, Greenberg G: Bones and Crohn's: risk factors associated with low bone mineral density in patients with Crohn's disease. Inflamm Bowel Dis 2004;10:220-228.
25. Lodder MC, de Jong Z, Kostense PJ, Molenaar ET, Staal K, Voskuyl AE, Hazes JM, Dijkmans BA, Lems WF: Bone mineral density in patients with rheumatoid arthritis: relation between disease severity and low bone mineral density. Ann Rheum Dis 2004;63:1576-1580.