Serum noncholesterol sterols in children with heterozygous familial hypercholesterolemia undergoing pravastatin therapy

Journal of Pediatrics

Volumn 148, Issue 2, 2006, Pages 241-246

  Hedman, Mia ^b   Miettinen, Tatu A ^b   Gylling, Helena ^b   Ketomäki, Anna ^b   Antikainen, Marjatta ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CAMPESTEROL; CHOLESTANOL; DESMOSTEROL; LATHOSTEROL; PRAVASTATIN; SITOSTEROL; STANOL ESTER; STEROL;

ARTICLE; CHOLESTEROL METABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FAMILIAL HYPERCHOLESTEROLEMIA; HUMAN; PRIORITY JOURNAL;

ADOLESCENT; ANTICHOLESTEREMIC AGENTS; CHILD; CHOLESTANOL; CHOLESTEROL; DESMOSTEROL; FEMALE; HETEROZYGOTE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; MALE; PHYTOSTEROLS; PRAVASTATIN; SITOSTEROLS; TRIGLYCERIDES;

EID: 33344456788     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2005.08.068     Document Type: Article

References (33)

1. M.S. Brown, P.T. Kovanen, J.L. Goldstein Regulation of plasma cholesterol by lipoprotein receptors Science 212 1981 628 635
2. P.T. Kovanen Regulation of plasma cholesterol by hepatic low-density lipoprotein receptors Am Heart J 113 1987 464 469
3. J. Jensen, D.H. Blankenhorn, V. Kornerup Coronary disease in familial hypercholesterolemia Circulation 36 1967 77 82
4. A. Wiegman, J. Rodenburg, S. de Jongh, J.C. Defesche, H.D. Bakker, J.J. Kastelein Family history and cardiovascular risk in familial hypercholesterolemia data in more than 1000 children Circulation 107 2003 1473 1478
5. R. Shamir, E.A. Fisher Dietary therapy for children with hypercholesterolemia Am Fam Physician 61 2000 675 682
6. S. Tonstad, J. Knudtzon, M. Sivertsen, H. Refsum, L. Ose Efficacy and safety of cholestyramine therapy in peripubertal and prepubertal children with familial hypercholesterolemia J Pediatr 129 1996 42 49
7. B.W. McCrindle, M.B. O'Neill, G. Cullen-Dean, E. Helden Acceptability and compliance with two forms of cholestyramine in the treatment of hypercholesterolemia in children a randomized, crossover trial J Pediatr 130 1997 266 273
8. S. Tonstad, L. Ose Colestipol tablets in adolescents with familial hypercholesterolaemia Acta Paediatr 85 1996 1080 1082
9. S.M. Grundy, E.H. Ahrens Jr, J. Davignon The interaction of cholesterol absorption and cholesterol synthesis in man J Lipid Res 10 1969 304 315
10. T. Heinemann, G.A. Kullak-Ublick, B. Pietruck, K. von Bergmann Mechanisms of action of plant sterols on inhibition of cholesterol absorption comparison of sitosterol and sitostanol Eur J Clin Pharmacol 40 Suppl 1 1991 S59 S63
11. M. Nissinen, H. Gylling, M. Vuoristo, T.A. Miettinen Micellar distribution of cholesterol and phytosterols after duodenal plant stanol ester infusion Am J Physiol Gastrointest Liver Physiol 282 2002 G1009 G1015
12. A. Tammi, T. Rönnemaa, H. Gylling, L. Rask-Nissilä, J. Viikari, J. Tuominen Plant stanol ester margarine lowers serum total and low-density lipoprotein cholesterol concentrations of healthy children the STRIP project J Pediatr 136 2000 503 510
13. A.M. Ketomäki, H. Gylling, M. Antikainen, M.A. Siimes, T.A. Miettinen Red cell and plasma plant stanol and sterol ester spreads in children with hypercholesterolemia J Pediatr 142 2003 524 531
14. C.L. Williams, M.C. Bollella, B.A. Strobino, L. Boccia, L. Campanoro Plant stanol ester and bran fiber in childhood effects on lipids, stool weight and stool frequency in preschool children J Am Coll Nutr 18 1999 572 581
15. E.A. Stein, D.R. Illingworth, P.O. Kwiterovich, C.A. Liacouras, M.A. Siimes, M.S. Jacobson Efficacy and safety of lovastatin in adolescent males with heterozygous familial hypercholesterolemia a randomized controlled trial JAMA 281 1999 137 144
16. S. de Jongh, L. Ose, T. Szamosi, C. Gagne, M. Lambert, R. Scott Efficacy and safety of statin therapy in children with familial hypercholesterolemia a randomized, double-blind, placebo-controlled trial with simvastatin Circulation 106 2002 2231 2237
17. A. Wiegman, B.A. Hutten, E. de Groot, J. Rodenburg, H.D. Bakker, H.R. Buller Efficacy and safety of statin therapy in children with familial hypercholesterolemia a randomized controlled trial JAMA 292 2004 331 337
18. M. Hedman, T. Matikainen, A. Föhr, S. Piippo, M. Nuutinen, M. Antikainen Efficacy and safety of pravastatin in children and adolescents with heterozygous familial hypercholesterolemia a prospective clinical follow-up study J Clin Endocrinol Metab 90 2005 1942 1952
19. M. Hedman, P.J. Neuvonen, M. Neuvonen, M. Antikainen Pharmacokinetics and pharmacodynamics of pravastatin in children with familial hypercholesterolemia Clin Pharmacol Ther 74 2003 178 185
20. A.F. Vuorio, K. Aalto-Setälä, U.M. Koivisto, H. Turtola, H. Nissen, P.T. Kovanen Familial hypercholesterolemia in Finland common, rare and mild mutations of the LDL receptor and their clinical consequences Ann Med 33 2001 410 421
21. J.A. Cuthbert, C.A. East, D.W. Bilheimer, P.E. Lipsky Detection of familial hypercholesterolemia by assaying functional low-density lipoprotein receptors on lymphocytes N Engl J Med 314 1986 879 883
22. W.T. Friedewald, R.I. Levy, D.S. Fredrickson Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of preparative ultracentrifuge Clin Chem 18 1972 499 502
23. T.A. Miettinen, R.S. Tilvis, Y.A. Kesäniemi Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population Am J Epidemiol 131 1990 20 31
24. A. Ketomäki, H. Gylling, M.A. Siimes, A. Vuorio, T.A. Miettinen Squalene and noncholesterol sterols in serum and lipoproteins of children with and without familial hypercholesterolemia Pediatr Res 53 2003 648 653
25. T.A. Miettinen, T.E. Strandberg, H. Gylling Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients relation to basal serum cholestanol Atherioscler Thromb Vasc Biol 20 2000 1340 1346
26. M.I. Uusitupa, T.A. Miettinen, P. Happonen, T. Ebeling, H. Turtola, E. Voutilainen Lathosterol and other noncholesterol sterols during treatment of hypercholesterolemia with lovastatin alone and with cholestyramine or guar gum Artherioscler Thromb 12 1992 807 813
27. T.A. Miettinen, H. Gylling, N. Lindbohm, T.E. Miettinen, R.A. Rajaratnam, H. Relas Serum noncholesterol sterols during inhibition of cholesterol synthesis by statins J Lab Clin Med 141 2003 131 137
28. T.A. Miettinen, H. Gylling Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose statin treatment Eur J Clin Med 33 2003 976 982
29. J.A. Halberat, C.A. Silagy, P. Finucane, R.T. Withers, P.A. Hamdorf Exercise training and blood lipids in hyperlipidemic and normolipidemic adults a meta-analysis of randomized, controlled trials Eur J Clin Nutr 53 1999 514 522
30. B.A. Hamelin, J. Turgeon Hydrophilicity/lipophilicity relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors Trends Pharmacol Sci 19 1998 26 27
31. T.A. Miettinen, H. Gylling Ineffective decrease of serum cholesterol by simvastatin in a subgroup of hypercholesterolemic coronary patients Atherosclerosis 164 2002 147 152
32. T.A. Miettinen, H. Gylling, T. Strandberg, S. Sarna Finnish 4S Investigators Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study BMJ 11 1998 1127 1130
33. J.M. McKenney Efficacy and safety of rosuvastatin in treatment of dyslipidemia Am J Health Syst Pharm 62 2005 1033 1047