Urinary aquaporin-2 in children with acute pyelonephritis

Pediatric Nephrology

Volumn 21, Issue 3, 2006, Pages 361-367

  Rodionova, Elena A ^a   Kuznetsova, Alla A ^b   Shakhmatova, Elena I ^a   Prutskova, Natalia ^a   Nielsen, Søren ^c   Holtbäck, Ulla ^d   Natochin, Yuri ^a   Zelenina, Marina ^d,e,f  

^a SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

^b SAINT PETERSBURG STATE PEDIATRIC MEDICAL UNIVERSITY   (Russian Federation)

^c AARHUS UNIVERSITY   (Denmark)

^d KAROLINSKA INSTITUTE   (Sweden)

^e INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Acute pyelonephritis; Kidney concentration capacity; Urinary excretion; Urinary tract infection; Water channels

Indexed keywords

AMPICILLIN; AQUAPORIN 2; AQUAPORIN 3; ARGIPRESSIN; CEFOTAXIME; GENTAMICIN; NITROFURAN; SULFANILAMIDE DERIVATIVE;

ACUTE PYELONEPHRITIS; ADOLESCENT; ANALYSIS OF VARIANCE; ARTICLE; CELL MEMBRANE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG TARGETING; FEMALE; HUMAN; IMMUNOBLOTTING; KIDNEY FUNCTION; MALE; POLYURIA; PRIORITY JOURNAL; PROTEIN URINE LEVEL; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; URINALYSIS; URINARY EXCRETION; URINE; URINE FLOW RATE; URINE OSMOLALITY;

ACUTE DISEASE; ADOLESCENT; AQUAPORIN 2; AQUAPORIN 3; ARGININE VASOPRESSIN; CHILD; CHILD, PRESCHOOL; CREATININE; FEMALE; HUMANS; IMMUNOBLOTTING; KIDNEY CONCENTRATING ABILITY; KIDNEY TUBULES, COLLECTING; MALE; OSMOLAR CONCENTRATION; POLYURIA; PYELONEPHRITIS; URINE;

EID: 33244469067     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-005-2101-8     Document Type: Article

References (26)

1. Jodal U, Lindberg U, Lincoln K (1975) Level diagnosis of symptomatic urinary tract infections in childhood. Acta Paediatr Scand 64:201-208
2. Åbyholm G, Monn E (1979) Intranasal DDAVP-test in the study of renal concentrating capacity in children with recurrent urinary tract infections. Eur J Pediatr 130:149-154
3. Berg U (1981) Renal function in acute febrile urinary tract infection in children: Pathophysiologic aspects on the reduced concentrating capacity. Kidney Int 20:753-758
4. Deen PM, Verdijk MA, Knoers NV, Wieringa B, Monnens LA, van Os CH, van Oost BA (1994) Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine. Science 264:92-95
5. Nielsen S, Chou CL, Marples D, Christensen EI, Kishore BK, Knepper MA (1995) Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane. Proc Natl Acad Sci USA 92:1013-1017
6. Sabolic I, Katsura T, Verbavatz JM, Brown D (1995) The AQP2 water channel: Effect of vasopressin treatment, microtubule disruption, and distribution in neonatal rats. J Membr Biol 143:165-175
7. Nguyen MK, Nielsen S, Kurtz I (2003) Molecular pathogenesis of nephrogenic diabetes insipidus. Clin Exp Nephrol 7:9-17 Clin Exp Nephrol 7 9-17
8. Kanno K, Sasaki S, Hirata Y, Ishikawa S, Fushimi K, Nakanishi S, Bichet DG, Marumo F (1995) Urinary excretion of aquaporin-2 in patients with diabetes insipidus. N Engl J Med 332:1540-1545
9. Rai T, Sekine K, Kanno K, Hata K, Miura M, Mizushima A, Marumo F, Sasaki S (1997) Urinary excretion of aquaporin-2 water channel protein in human and rat. J Am Soc Nephrol 8:1357-1362
10. Wen H, Frokiaer J, Kwon TH, Nielsen S (1999) Urinary excretion of aquaporin-2 in rat is mediated by a vasopressin-dependent apical pathway. J Am Soc Nephrol 10:1416-1429
11. Pisitkun T, Shen RF, Knepper MA (2004) Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci USA 101:13368-13373
12. Elliot S, Goldsmith P, Knepper M, Haughey M, Olson B (1996) Urinary excretion of aquaporin-2 in humans: A potential marker of collecting duct responsiveness to vasopressin. J Am Soc Nephrol 7:403-409
13. Popper H, Mandel EE, Mayer H (1937) Zur Kreatininbestimmung in Blute. Biochem Z 291:354-367
14. Natochin YV, Ryabov SI, Kayukov IG, Lavrova EA, Monin YG, Shakhmatova EI, Emanuel VI (1980) Indicators of water and mineral homeostasis and their variability. Hum Physiol 6:273-276
15. Deen PM, van Aubel RA, van Lieburg AF, van Os CH (1996) Urinary content of aquaporin 1 and 2 in nephrogenic diabetes insipidus. J Am Soc Nephrol 7:836-841
16. Saito T, Ishikawa SE, Sasaki S, Nakamura T, Rokkaku K, Kwakami A, Honda K, Marumo F, Saito T (1997) Urinary excretion of aquaporin-2 in the diagnosis of central diabetes insipidus. J Clin Endocrinol Metab 82:1823-1827
17. Saito T, Ishikawa SE, Ando F, Okada N, Nakamura T, Kusaka I, Higashiyama M, Nagasaka S, Saito T (1998) Exaggerated urinary excretion of aquaporin-2 in the pathological state of impaired water excretion dependent upon arginine vasopressin. J Clin Endocrinol Metab 83:4034-4040
18. Martin PY, Abraham WT, Lieming X, Olson BR, Oren RM, Ohara M, Schrier RW (1999) Selective V2-receptor vasopressin antagonism decreases urinary aquaporin-2 excretion in patients with chronic heart failure. J Am Soc Nephrol 10:2165-2170
19. Matsumoto T, Takeya M, Takuwa S, Hiquchi E, Fujimatsu A, Maeshiro H, Ito Y, Kanno K, Sasaki S, Kato H (2000) Suppressed urinary excretion of aquaporin-2 in an infant with primary polydipsia. Pediatr Nephrol 14:48-52
20. Baumgarten R, van de Pol MH, Deen PM, van Os CH, Wetzels JF (2000) Dissociation between urine osmolality and urinary excretion of aquaporin-2 in healthy volunteers. Nephrol Dial Transplant 15:1155-1161
21. Serlachius E, Sundelin B, Eklof AC, Jahnke M, Laestadius A, Aperia A (1997) Pyelonephritis provokes growth retardation and apoptosis in infant rat renal cortex. Kidney Int 51:1855-1862
22. Donald RA, Bailey RR, Hart D, Livesey JH, Evans MJ, Mattioli L, MacDonald J, Smith AH (1994) The plasma interleukin-6 and stress hormone responses to acute pyelonephritis. J Endocrinol Invest 17:263-268
23. Gonick HC, Goldberg G, Rubini ME, Guze LB (1965) Functional abnormalities in experimental pyelonephritis. I. Studies of concentrating ability. Nephron 2:193-206
24. Kaye D, Rocha H (1970) Urinary concentrating ability in early experimental pyelonephritis. J Clin Invest 49:1427-1437
25. Armsen TR, Joppich R, Schubert G, Edel HH (1975) Single nephron study of intrarenal urea handling in experimental pyelonephritis. Res Exp Med (Berl) 165:141-152
26. Levison SP, Pitsakis PG, Levison ME (1982) Free water reabsorption during saline diuresis in experimental enterococcal pyelonephritis in rats. J Lab Clin Med 99:474-480