Living donor liver transplantation in high-risk vs. low-risk patients: Optimization using statistical models

Liver Transplantation

Volumn 12, Issue 2, 2006, Pages 231-239

  Durand, François ^a   Belghiti, Jacques ^a   Troisi, Roberto ^b   Boillot, Olivier ^c   Gadano, Adrian ^d   Francoz, Claire ^a   de Hemptinne, Bernard ^b   Mallet, Alain ^e   Valla, Dominique ^a   Golmard, Jean Louis ^e  

^a BEAUJON HOSPITAL   (France)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d HOSPITAL ITALIANO DE BUENOS AIRES   (Argentina)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ADULT; ARTICLE; CADAVER DONOR; CONTROLLED STUDY; FEMALE; HEPATITIS C; HIGH RISK PATIENT; HUMAN; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; SIMULATION; STATISTICAL ANALYSIS; STATISTICAL MODEL; SURVIVAL;

ADOLESCENT; ADULT; AGE FACTORS; CAUSE OF DEATH; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; LIVER FAILURE; LIVER TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; MODELS, STATISTICAL; PATIENT SELECTION; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEX FACTORS; SURVIVAL ANALYSIS; TISSUE AND ORGAN PROCUREMENT; WAITING LISTS;

EID: 33244459104     PISSN: 15276465     EISSN: None     Source Type: Journal    
DOI: 10.1002/lt.20700     Document Type: Article

References (25)

1. Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996;334:693-699.
2. Freeman RB, Wiesner RH, Edwards E, Harper A, Merion R, Wolfe R. Results of the first year of the new liver allocation plan. Liver Transpl 2004;10:7-15.
3. Wiesner R, Edwards E, Freeman R, Harper A, Kim R, Kamath P, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology 2003;124: 91-96.
4. Devlin J, O'Grady J. Indications for referral and assessment in adult liver transplantation: a clinical guideline. British Society of Gastroenterology. Gut 1999;45(Suppl 6):VII-VI22.
5. Yao FY, Bass NM, Ascher NL, Roberts JP. Liver transplantation for hepatocellular carcinoma: lessons from the first year under the Model of End-Stage Liver Disease (MELD) organ allocation policy. Liver Transpl 2004;10:621-630.
6. Pruett TL. The allocation of livers for transplantation: a problem of Titanic consideration. Hepatology 2002;35:960-963.
7. Freeman RB Jr, Edwards EB. Liver transplant waiting time does not correlate with waiting list mortality: implications for liver allocation policy. Liver Transpl 2000;6: 543-552.
8. Maddala YK, Stadheim L, Andrews JC, Burgart LJ, Rosen CB, Kremers WK, Gores G. Drop-out rates of patients with hepatocellular cancer listed for liver transplantation: outcome with chemoembolization. Liver Transpl 2004;10:449-455.
9. Liu CL, Lam B, Lo CM, Fan ST. Impact of right-lobe live donor liver transplantation on patients waiting for liver transplantation. Liver Transpl 2003;9:863-869.
10. Ghobrial RM, Saab S, Lassman C, Lu DS, Raman S, Limanond P, et al. Donor and recipient outcomes in right lobe adult living donor liver transplantation. Liver Transpl 2002;8:901-909.
11. Marcos A, Ham JM, Fisher RA, Olzinski AT, Posner MP. Single-center analysis of the first 40 adult-to-adult living donor liver transplants using the right lobe. Liver Transpl 2000;6:296-301.
12. Chen CL, Fan ST, Lee SG, Makuuchi M, Tanaka K. Living-donor liver transplantation: 12 years of experience in Asia. Transplantation 2003;75:S6-S11.
13. Brown RS Jr, Russo MW, Lai M, Shiffman ML, Richardson MC, Everhart JE, Hoofnagle JH. A survey of liver transplantation from living adult donors in the United States. N Engl J Med 2003;348:818-825.
14. Bambha K, Kim WR, Kremers WK, Therneau TM, Kamath PS, Wiesner R, et al. Predicting survival among patients listed for liver transplantation: an assessment of serial MELD measurements. Am J Transplant 2004;4:1798-1804.
15. Llovet JM, Fuster J, Bruix J. Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection vs. transplantation. Hepatology 1999;30:1434-1440.
16. Trotter JF, Osgood MJ. MELD scores of liver transplant recipients according to size of waiting list: impact of organ allocation and patient outcomes. JAMA 2004:291:1871-1874.
17. Harper AM, Taranto SE, Edwards EB. The OPTN waiting list, 1988-2001. Clan Transpl 2002:79-92.
18. Jacob M, Copley LP, Lewsey JD, Gimson A, Toogood GJ, Rela M, Van Der Meulen JH. Pretransplant MELD score and post liver transplantation survival in the UK and Ireland. Liver Transpl 2004;10:903-907.
19. Desai NM, Mange KC, Crawford MD, Abt PL, Frank AM, Markmann JW, et al. Predicting outcome after liver transplantation: utility of the model for end-stage liver disease and a newly derived discrimination function. Transplantation 2004;77:99-106.
20. Onaca NN, Levy MF, Sanchez EQ, Chinnakotla S, Fasola CG, Thomas MJ, et al. A correlation between the pretransplantation MELD score and mortality in the first two years after liver transplantation. Liver Transpl 2003;9:117-123.
21. Kulik L, Abecassis M. Living donor liver transplantation for hepatocellular carcinoma. Gastroenterology 2004;127: S277-282.
22. Todo S, Furukawa H. Living donor liver transplantation for adult patients with hepatocellular carcinoma: experience in Japan. Ann Surg 2004;240:451-459; discussion 459-461.
23. Lo CM, Fan ST, Liu CL, Yong BH, Wong Y, Lau GK, et al. Lessons learned from one hundred right lobe living donor liver transplants. Ann Surg 2004;240:151-158.
24. Gondolesi GE, Roayaie S, Munoz L, Kim-Schluger L, Schiano T, Fishbein TM, et al. Adult living donor liver transplantation for patients with hepatocellular carcinoma: extending UNOS priority criteria. Ann Surg 2004;239: 142-149.
25. Roberts JP. Role of adult living liver donation in patients with hepatocellular cancer. Liver Transpl 2003:9:S60-S63.