Corticosteroid use in the intensive care unit: At what cost?

Archives of Surgery

Volumn 141, Issue 2, 2006, Pages 145-149

  Britt, Rebecca C ^a   Devine, Alicia ^a   Swallen, Karen C ^b   Weireter, Leonard J ^a   Collins, Jay N ^a   Cole, Frederic J ^a   Britt, L D ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; HYDROCORTISONE; METHYLPREDNISOLONE; PREDNISONE;

ADRENAL INSUFFICIENCY; APACHE; ARTICLE; BLOOD FLOW; BURN; CONFIDENCE INTERVAL; CONTROLLED STUDY; EMERGENCY HEALTH SERVICE; HEAD INJURY; HUMAN; INJURY SCALE; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MORBIDITY; MORTALITY; MULTIVARIATE ANALYSIS; OPTIC NEURITIS; OUTCOME ASSESSMENT; PNEUMONIA; PRIORITY JOURNAL; SCORING SYSTEM; SEPSIS; SEPTIC SHOCK; SPINAL CORD INJURY; STATISTICAL SIGNIFICANCE; STRIDOR; URINARY TRACT INFECTION; VENTILATOR;

ADULT; BURN UNITS; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HOSPITAL MORTALITY; HUMANS; INCIDENCE; LENGTH OF STAY; MIDDLE AGED; PNEUMONIA; RETROSPECTIVE STUDIES; SEPSIS; TREATMENT OUTCOME; URINARY TRACT INFECTIONS;

EID: 33244457586     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: 10.1001/archsurg.141.2.145     Document Type: Article

References (14)

1. Schumer W. Steroids in the treatment of clinical septic shock. Ann Surg. 1976;184:333-341.
2. Veterans Administration Systemic Sepsis Cooperative Study Group. Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N Engl J Med. 1987;317:659-665.
3. Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA, Bulk RA. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med. 1987;317:653-658.
4. Cronin L, Cook DJ, Carlet J, et al. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit Care Med. 1995;23:1430-1439.
5. Annane D, Sebille V, Carpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002;288:862-871.
6. Dale DC, Petersdorf RG. Corticosteroids and infectious diseases. Med Clin North Am. 1973;57:1277-1287.
7. Napolitano LM, Faist E, Wichmann MW, Coimbra R. Immune dysfunction in trauma. Surg Clin North Am. 1999;79:1385-1416.
8. DeMaria EJ, Reichman W, Kenney PR, Armitage JM, Gann DS. Septic complications of corticosteroid administration after central nervous system trauma. Ann Surg. 1985;202:248-252.
9. Gerndt SJ, Rodriguez JL, Pawlik JW, et al. Consequences of high-dose steroid therapy for acute spinal cord injury. J Trauma. 1997;42:279-284.
10. Bracken MB, Shepard MJ, Collins WF, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal cord injury: results of the Second National Acute Spinal Cord Injury Study. N Engl J Med. 1990;322:1405-1411.
11. Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, Kupfer Y. Corticosteroids for treating severe sepsis and septic shock. Cochrane Database Syst Rev. 2004;(1):CD002243.
12. Markovitz BP, Randolph AG. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children, and adults. Cochrane Database Syst Rev. 2000;(2):CD001000.
13. Meade MO, Guyatt GH, Cook DJ, Sinuff T, Butler R. Trials of corticosteroids to prevent postextubation airway complications. Chest. 2001;120(suppl):464S-468S.
14. Levin LA, Beck RW, Joseph MP, Seiff S, Kraker R. The treatment of traumatic optic neuropathy: the International Optic Nerve Trauma Study. Ophthalmology. 1999;106:1268-1277.