Nitric oxide and reactive oxygen species production causes progressive damage in rats after cessation of silica inhalation

Toxicological Sciences

Volumn 90, Issue 1, 2006, Pages 188-197

  Porter, Dale W ^a   Millecchia, Lyndell L ^a   Willard, Patsy ^a   Robinson, Victor A ^a   Ramsey, Dawn ^a   McLaurin, Jeffery ^a   Khan, Amir ^a   Brumbaugh, Kurt ^a   Beighley, Christoper M ^a   Teass, Alexander ^a   Castranova, Vincent ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Nitric oxide; Oxidative stress; Rat; Reactive oxygen species; Silica inhalation

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DISEASE SEVERITY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; LUNG LAVAGE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT;

ADMINISTRATION, INHALATION; AIR POLLUTANTS, OCCUPATIONAL; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; INHALATION EXPOSURE; LUNG; MACROPHAGES, ALVEOLAR; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, INBRED F344; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; SILICOSIS; SPECIFIC PATHOGEN-FREE ORGANISMS; TIME FACTORS;

ANIMALIA;

EID: 33144465057     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfj075     Document Type: Article

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