Lymph node enlargement during combination therapy for chronic Hepatitis C with pegylated interferon alpha and ribavirin: Harmless reaction or harmful disease?

Swiss Medical Weekly

Volumn 136, Issue 3-4, 2006, Pages 65-67

  Wilhelmi, Martin ^a   Gubler, Christoph ^a   Renner, Eberhard L ^a   Müllhaupt, Beat ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Chronic hepatitis C; Lymph node enlargement; Pegylated interferon; Ribavirin

Indexed keywords

PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; RIBAVIRIN;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEPATITIS C; HUMAN; IMMUNOMODULATION; LIVER FIBROSIS; LIVER HILUS; LYMPH NODE ENLARGEMENT; LYMPHADENOPATHY; MALE; NONHODGKIN LYMPHOMA; TUBERCULOSIS;

EID: 33144463733     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Muller P, Renou C, Harafa A, Jouve E, Kaplanski G, Ville E et al. Lymph node enlargement within the hepatoduodenal ligament in patients with chronic hepatitis C reflects the immunological cellular response of the host. J Hepatol 2003;29:807-13.
2. Dietrich CF, Lee JH, Herrmann G, Treuber G, Roth WK, Caspary WF, Zeuzem S. Enlargement of perihepatic lymph nodes in relation to liver histology and viremia in patients with chronic hepatitis C. Hepatology 1997;26:467-72.
3. Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R et al. Peginterferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C; a randomised trial. Lancet 2001;358:958-65.
4. Tahan V, Ozseker F, Guneylioglu D, Baran A, Ozaras R, Mert A et al. Sarcoidosis after use of interferon for chronic hepatitis C. Dig Dis Sci 2003;48:169-73.
5. Barnes E, Harcourt G, Brown D, Lucas M, Phillips R, Dusheiko G et al. The dynamics of T-lymphocytes responses during combination therapy of chronic hepatitis C virus infection. Hepatology 2002;36:743-54.
6. Kuniyoshi M, Nakamuta M, Sakai H, Enjoji M, Kinukawa N, Kotoh K et al. Prevalence of hepatitis B or C virus infections in patients with non-Hodgkins lymphoma. J Gastro and Hepa 2001;16;215-9.
7. Okuno H, Ikeda H, Fukushima S, Hirota T, Kadota Y, Shiozaki Y et al. A case of tuberculous pleurisy aggravated by interferon treatment for chronic hepatitis C. Nippon Shokakibyo Gakkai Zasshi 1995;92:1071-5.
8. Bouchonnet F, Boechat N, Bonay M, Hance A. Alpha/Beta Interferon impairs the ability of human macrophages to control growth of Mycobacterium bovis BCG; Infection and immunity 2002; June; 3020-5.