Zn-α2-glycoprotein, an MHC class I-related glycoprotein regulator of adipose tissues: Modification or abrogation of ligand binding by site-directed mutagenesis

Biochemistry

Volumn 45, Issue 7, 2006, Pages 2035-2041

  McDermott, Lindsay C ^a,b,d   Freel, June A ^a   West, Anthony P ^c   Bjorkman, Pamela J ^c   Kennedy, Malcolm W ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; LIPIDS; MOLECULAR STRUCTURE; MUTAGENESIS; TISSUE; X RAY CRYSTALLOGRAPHY;

ADIPOSE TISSUES; CANCER CACHEXIA; I-RELATED GLYCOPROTEIN REGULATOR; SITE-DIRECTED MUTAGENESIS;

PROTEINS;

ADIPOCYTOKINE; ALANINE; ALPHA2 GLYCOPROTEIN; AMINO ACID; AMPHOPHILE; ARGININE; GLYCOPROTEIN; MACROGOL; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MUTANT PROTEIN; POLYUNSATURATED FATTY ACID; SOLVENT; ZINC; 11 (DANSYLAMINO)UNDECANOIC ACID; 11-(DANSYLAMINO)UNDECANOIC ACID; DANSYL CHLORIDE; FATTY ACID; LIGAND; SEMINAL PLASMA PROTEIN; ZN ALPHA 2 GLYCOPROTEIN; ZN-ALPHA-2-GLYCOPROTEIN;

ADIPOSE TISSUE; ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CACHEXIA; CONTROLLED STUDY; CRYSTAL STRUCTURE; FLUORESCENCE; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SOLVATION; SURFACE CHARGE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECT; GENETICS; HUMAN; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; SEQUENCE ALIGNMENT; SPECTROFLUOROMETRY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CIRCULAR DICHROISM; DANSYL COMPOUNDS; FATTY ACIDS; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; SEMINAL PLASMA PROTEINS; SEQUENCE ALIGNMENT; SPECTROMETRY, FLUORESCENCE;

EID: 33144460013     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051881v     Document Type: Article

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