Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC

Journal of Chromatographic Science

Volumn 43, Issue 7, 2005, Pages 348-350

  Puri, S C ^a   Handa, G ^a   Bhat, B A ^a   Gupta, V K ^a   Amna, T ^a   Verma, N ^a   Anand, R ^a   Dhar, K L ^a   Qazi, G N ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

NOTHAPODYTES FOETIDA;

9 METHOXYCAMPTOTHECIN; 9-METHOXYCAMPTOTHECIN; CAMPTOTHECIN; DRUG DERIVATIVE;

ANGIOSPERM; ARTICLE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY;

ANGIOSPERMS; CAMPTOTHECIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; MASS SPECTROMETRY;

EID: 32944481707     PISSN: 00219665     EISSN: 00219665     Source Type: Journal    
DOI: 10.1093/chromsci/43.7.348     Document Type: Article

References (7)

1. T.R. Govindachari and N. Vishwanathan. Alkaloids of Mappia foetida. Phytochemistry 11: 3529 (1972).
2. M. Arisawa, S.P. Gunasekera, G.A. Cordell, and N.R. Farmsworth. Plant anticancer agents XXI constituents of Merrillodendeon megacarpum. Planta Med. 43: 404 (1981).
3. X. Zhang and J. Bao. Extracting Camptothecin from Nothapodytes. Faming Zhuanli Shenquing Cronkai Shuomingshu CN 1,045,266 (Cl.C07D491/147), 12 September 1990. CA. 114 1644601v.
4. S.N. Sharma, S.C. Puri, T. N. Srivastava, G. Handa, and B.L. Kaul. Enhancement of seed germination in Nothapodytes foetida. JMAPS 22: 206-10 (2000).
5. S. Broglia, L. Verotta, and M. Battislini. Application of high speed countercurrent chromatography to the separation of Camptothecin and 9-methoxycamptothecin. Fitoterapia. LXV(6): 522-23 (1994).
6. M.C. Wani, C.E. Cook, K.H. Palmer, A.T. McPhail, and G.A. Sim. Plant antitumor agents I. The isolation and structure of camptothecin, a novel alkaloidal leukaemia and tumor inhibitor from Camptotheca accuminata. J. Amer. Chem. Soc. 88: 3888-90 (1966).
7. 13CNMR Assignments of Camptothecine and 10-hydroxycamptothecine. J. Nat. Prod. 53: 186-89 (1990).