A method for measuring the decay time of hyperpolarized 129Xe magnetization in rat brain without estimation of RF flip angles

Magnetic Resonance in Medical Sciences

Volumn 4, Issue 1, 2005, Pages 19-25

  Wakai, Atsushi ^a,b   Nakamura, Kazuhiro ^a,b   Kershaw, Jeff ^a,b   Kondoh, Yasushi ^a   Wright, David ^a,b   Kanno, Iwao ^a  

^a RESEARCH INSTITUTE FOR BRAIN AND BLOOD VESSELS AKITA   (Japan)

^b Akita Industry Promotion Foundation   (Japan)

Author keywords

Brain tissue; CBF; Laser polarized Xe; Relaxation time; Washout

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT; XENON;

AEROSOL; ALGORITHM; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BRAIN; BRAIN MAPPING; COMPUTER SIMULATION; EVALUATION; INHALATIONAL DRUG ADMINISTRATION; KINETICS; MALE; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; SPIN LABELING; SPRAGUE DAWLEY RAT;

ADMINISTRATION, INHALATION; AEROSOLS; ALGORITHMS; ANIMALS; BRAIN; BRAIN MAPPING; COMPUTER SIMULATION; CONTRAST MEDIA; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLIC CLEARANCE RATE; MODELS, NEUROLOGICAL; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS; XENON ISOTOPES;

EID: 32944475952     PISSN: 13473182     EISSN: 18802206     Source Type: Journal    
DOI: 10.2463/mrms.4.19     Document Type: Article

References (25)

1. 129Xe in human brain analyzed by an uptake model. Magn Reson Med 2004; 51:843-847.
2. Venkatesh AK, Hong KS, Kubatina L, et al. Using dynamic hyperpolarized xenon MR to measure brain perfusion. Proc. Intl. Soc. Magn Reson Med 2001; 9:951.
3. 129Xe. Magn Reson Med 1997; 38:695-698.
4. 129Xe. Proc. Intl. Soc. Magn Reson Med 2004; 11:767.
5. Duhamel G, Choquet P, Grillon E, et al. Xenon-129 MR imaging and spectroscopy of rat brain using arterial delivery of hyperpolarized xenon in a lipid emulsion. Magn Reson Med 2001; 46:208-212.
6. 129Xe. Proc. Intl. Soc. Magn Reson Med 2004; 11:768.
7. 129Xe spectra from intact and ECAWPPA obstructed rat head. Proc. Int. Soc. Magn Reson Med 2004; 11:770.
8. 129Xe. Nucl Instrum Meth Phys Res A 1998; 402:461-463.
9. Martin CC, Williams RF, Gao JH, Nickerson DH, Jinhu Xiong BS, Fox PT. The pharmacokinetics of hyperpolarized xenon: implications for cerebral MRI. J Magn Reson Imaging 1997; 7:848-854.
10. 129Xe magnetic resonance in humans. Magn Reson Med 1996; 36:340-344.
11. 129Xe in rat tissue homogenates at 9.4T. Magn Reson Med 1999; 41:933-938.
12. 129Xe spectra from the heads of rats with and without ligation of the external carotid and pterygopalatine arteries. Magn Reson Med 2005; 53:528-534.
13. Liang ZP, Lauterbur PC. Principles of magnetic resonance imaging. New York: The Institute of Electrical and Electronics Engineers, Inc., 2000; 57-105.
14. 129Xe Nuclei. J Magn Reson 1997; 126:58-56.
15. 129Xenon gas. Jpn J Magn Reson Med 2001; 21:109-118.
16. 129Xe gas: size dependency and wall effect of the T1 relaxation time in glass and gelatin bulbs. J Magn Reson 2001; 150:156-160.
17. 129Xe in human blood and living rat chest. Magn Reson Med Sci 2003; 2:189-194.
18. 129Xe optical pumpingW spin exchange and delivery system for magnetic resonance spectroscopy and imaging studies. Rev Sci Instrum 1999; 70:1546-1552.
19. 129Xe. Appl Phys Lett 1996; 69:1668-1670.
20. Larsen RJ, Marx ML. An introduction to mathematical statistics and its applications. Upper Saddle River, New Jersey: Prentice Hall International, Inc., 2001; 310-323.
21. 129Xe magnetization in vivo. Magn Reson Med 1999; 42:1137-1145.
22. Wolber J, Cherubini A, Dzik-Jurasz ASK, Leach MO, Bifone A. Spin-lattice relaxation of laserpolarized xenon in human blood. Proc. Natl. Acad. Sci. USA, 1999; 96:3664-3669.
23. Gjedde A, Caronna JJ, Hindfelt B, Plum F. Whole-brain blood flow and oxygen metabolism in the rat during nitrous oxide anesthesia. Am J Physiol 1975; 229:113-118.
24. Golman K, Ardenkjær-Larsen JH, Petersson JS, Månsson S, Leunbach I. Molecular imaging with endogenous substances. Proc. Natl. Acad. Sci. USA, 2003; 100:10435-10439.
25. Johansson E, Månsson S, Wirestan R, et al. Cerebral perfusion assessment by bolus tracking using hyperpolarized 13C. Magn Reson Med 2004; 51:464-472.