Effect of Lactobacillus GG on intestinal integrity in Malawian children at risk of tropical enteropathy

American Journal of Clinical Nutrition

Volumn 82, Issue 5, 2005, Pages 1040-1045

  Galpin, Lauren ^a,b   Manary, Mark J ^a,b,c,e   Fleming, Katherine ^a   Ou, Ching Nan ^c   Ashorn, Per ^d   Shulman, Robert J ^c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MALAWI   (Malawi)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d TAMPERE UNIVERSITY HOSPITAL   (Finland)

^e ST LOUIS CHILDREN S HOSPITAL   (United States)

Author keywords

Children; Lactobacillus GG; Malawi; Probiotics; Ratio of lactulose to mannitol; Tropical enteropathy

Indexed keywords

LACTULOSE; MANNITOL; PLACEBO; PROBIOTIC AGENT; SUCROSE; SUGAR; GASTROINTESTINAL AGENT; SWEETENING AGENT;

ANTHROPOMETRY; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DOSE RESPONSE; DRUG CAPSULE; DRUG EFFECT; DRUG EXCRETION; ENTEROPATHY; HUMAN; INTESTINE FUNCTION; LACTOBACILLUS; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; RISK FACTOR; SANITATION; TREATMENT OUTCOME; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; FEMALE; INTESTINE ABSORPTION; INTESTINE MUCOSA; MALAWI; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; T LYMPHOCYTE; TROPICAL MEDICINE; URINE;

BACTERIA (MICROORGANISMS); LACTOBACILLUS;

CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL DISEASES; INTESTINAL MUCOSA; LACTOBACILLUS; LACTULOSE; MALAWI; MALE; MANNITOL; PROBIOTICS; RISK FACTORS; SUCROSE; SWEETENING AGENTS; T-LYMPHOCYTES; TREATMENT OUTCOME; TROPICAL MEDICINE;

EID: 32944465461     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/82.5.1040     Document Type: Article

References (34)

1. Menzies IS, Zuckerman MJ, Nukajam WS, et al. Geography of intestinal permeability and absorption. Gut 1999;44:483-9.
2. Campbell DI, Murch SH, Elia M, et al. Chronic T cell-mediated enteropathy in rural West African children: relationship with nutritional status and small bowel function. Pediatr Res 2003;54:306-11.
3. Kelly P, Menzies I, Crane R, et al. Responses of small intestine architecture and function over time to environmental factors in a tropical population. Am J Trop Med 2004;70:412-9.
4. Brown KH, Khatun M, Ahmed G. Relationship of the xylose absorption status of children in Bangladesh to their absorption of macronutrients from local diets. Am J Clin Nutr 1981;34:1540-7.
5. Chacko A, Begum A, Mathan VI. Absorption of nutrient energy in southern Indian control subjects and patients with tropical sprue. Am J Clin Nutr 1984;40:771-5.
6. Ukabam SD, Cooper BT. Small intestinal permeability as an indicator of jejunal mucosal recovery in patients with celiac sprue and gluten free diet. J Clin Gastroenterol 1985;7:232-6.
7. Zhang Y, Lee B, Thompson M, et al. Lactulose-mannitol intestinal permeability test in children with diarrhea caused by rotavirus and cryptosporidium. Diarrhea Working Group, Peru. J Pediatr Gastroenterol Nutr 2000;31:16-21.
8. Chen P, Soares AM, Lima AAM, et al. Association of vitamin A and zinc status with altered intestinal permeability: analyses of cohort data from northeast Brazil. J Health Popul Nutr 2003;21:309-15.
9. Goto K, Chew F, Torún B, Peerson JM, Brown KH. Epidemiology of altered intestinal permeability to lactulose and mannitol in Guatemalan infants. J Pediatr Gastroenterol Nutr 1999;28:282-90.
10. Lunn PG, Northrop-Clewes CA, Downes RM. Intestinal permeability, mucosal injury and growth faltering in Gambian infants. Lancet 1991;338:907-10.
11. Fagundes-Neto U, Viaro T, Wehba J, da Silva Patricio FR, Machado NL. Tropical enteropathy (environmental enteropathy) in early childhood: a syndrome caused by contaminated environment. J Trop Paediatr 1984;30:204-9.
12. Fagundes-Neto U, do Vale Martins MC, da Silva Lima FL, Patricio FR, Toledo MR. Asymptomatic environmental enteropathy among slum-dwelling infants. J Am Coll Nutr 1994;13:51-6.
13. Oyemade A, Omokhodion FO, Olawuyi JF, Sridhar MKC, Olaseha IO. Environmental and personal hygiene practices: risk actors for diarrhoea among children of Nigerian market women. J Diarrhoeal Dis Res 1998;16:241-7.
14. Batt RM, Hall EJ, McLean L, Simpson KW. Small intestinal bacterial overgrowth and enhanced intestinal permeability in healthy beagles. Am J Vet Res 1992;53:1935-40.
15. Ouwehand AC, Kirjavainen PV, Gronlund M-M, Isolauri E, Salminen SJ. Adhesion of probiotic micro-organisms to intestinal mucus. Int Dairy J 1999;9:623-30.
16. Goldin BR, Gorbach SL, Saxelin ML, Barakat S, Gualtieri BS, Salminen S. Survival of Lactobacillus species (strain GG) in human gastrointestinal tract. Dig Dis Sci 1992;37:121-8.
17. Isolauri E, Juntunen M, Rautanen T, Sillanaukee P, Koivula T. A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics 1991;88:90-7.
18. Kuisma J, Mentula S, Jarvinen H, Kahri A, Saxelin M, Farkkila M. Effect of Lactobacillus rhamnosus GG on ileal pouch inflammation and microbial flora. Aliment Pharmacol Ther 2003;17:509-15.
19. Vanderhoof JA, Young RJ, Murray N, Kaufman SS. Treatment strategies for small bowel bacterial overgrowth in short bowel syndrome. J Pediatr Gastroenterol Nutr 1998;27:155-60.
20. Kalliomaki M, Salminen S, Arvilommi H, et al. Probiotic in primary prevention of atopic disease: a randomized, placebo-controlled trial. Lancet 2001;357:1076-9.
21. Meddings JB, Gibbins I. Discrimination of site-specific alterations in gastrointestinal permeability in the rat. Gastroenterology 1998;114:83-92.
22. Vera JF, Gotteland M, Chavez E, Vial MT, Kakarieka E, Brunser O. Sucrose permeability in children with gastric damage and Helicobacter pylori infection. J Pediatr Gastroenterol Nutr 1997;24:506-11.
23. Catassi C, Pierani P, Natalini G, Gabrielli O, Coppa GV, Giorgi PL. Clinical application of a simple HPLC method for the sugar intestinal permeability test. J Pediatr Gastroenterol Nutr 1991;12:209-12.
24. Shulman RJ, Schanler RJ, Lau C, Heitkemper M, Ou CN, Smith EO. Early feeding, antenatal glucocorticoids, and human milk decrease intestinal permeability in preterm infants. Pediatr Res 1998;44:519-23.
25. Brewster DR, Manary MJ, Menzies IS, O'Loughlin EV, Henry RL. Intestinal permeability in kwashiorkor. Arch Dis Child 1997;76:236-41.
26. van Elburg RM, Uil JJ, Kokke FTM, et al. Repeatability of the sugar-absorption test, using lactulose and mannitol, for measuring intestinal permeability of sugars. J Pediatr Gastroenterol Nutr 1995;20:184-8.
27. Campbell DI, Lunn PG, Elias M. Age-related association of small intestinal mucosal enteropathy with nutritional status in rural Gambian children. Br J Nutr 2002;88:499-505.
28. Oberhelman RA, Sheen P, Gilman RG, Cabrera L, Madico G. A placebo-controlled study of Lactobacillus GG colonization in 1-3 year-old Peruvian children. Am J Trop Med Hyg 1995;52:389-92.
29. Lima AA, Brito LF, Ribeiro HB, et al. Intestinal barrier function and weight gain in malnourished children taking glutamine supplemented enteral formula. J Pediatr Gastroenterol Nutr 2005;40:28-35.
30. Rosenfeldt V, Benfeldt E, Valerius NH, Paerrehaard A, Michaelsen KF. Effect of probiotics on gastrointestinal symptoms and small intestinal permeability in children with atopic dermatitis. J Pediatr 2004;145:612-6.
31. Nathavitharana KA, Lloyd DR, Raafat F, Brown GA, McNeish AS. Urinary mannnitol:lactulose excretion ratios and jejunal mucosal structure. Arch Dis Child 1988;63:1054-9.
32. Travis S, Menzies I. Intestinal permeability: functional assessment and significance. Clin Sci 1992;82:471-88 (editorial).
33. Gotteland M, Corvalan A, Sarmiento F, et al. Gastric permeability is not increased in children colonized by CagA-positive strains of Helicobacter pylori. Dig Liver Dis 2001;33:750-4.
34. Hooper LV, Gordon JI. Commensal host-bacterial relationships in the gut. Science 2001;292:1115-8.