Ultraviolet photography of the in vivo human cornea unmasks the Hudson-Stähli line and physiologic vortex patterns

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 10, 2005, Pages 3616-3622

  Every, Sean G ^a   Leader, John P ^a   Molteno, Anthony C B ^a   Bevin, Tui H ^a   Sanderson, Gordon ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; FERRITIN; IRON;

ADULT; AGED; ARTICLE; BIOMETRY; CONTACT LENS; CORNEA DISEASE; CORNEA EPITHELIUM; EYE PHOTOGRAPHY; FEMALE; HUDSON STAHLI LINE; HUMAN; IMAGE ANALYSIS; IN VIVO STUDY; KERATOPATHY; MAJOR CLINICAL STUDY; MALE; PHYSIOLOGY; PRIORITY JOURNAL; RADIATION ABSORPTION; ULTRAVIOLET PHOTOGRAPHY; CHEMICALLY INDUCED DISORDER; CORNEA; HISTOLOGY; METABOLISM; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PHOTOGRAPHY; ULTRAVIOLET RADIATION;

ADULT; AGED; AGED, 80 AND OVER; AMIODARONE; CORNEA; CORNEAL DISEASES; FEMALE; FERRITINS; HUMANS; IRON; MALE; MIDDLE AGED; PHOTOGRAPHY; ULTRAVIOLET RAYS;

EID: 32944462818     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-1455     Document Type: Article

References (66)

1. Lunnon RJ. Reflected ultraviolet photography of human tissues. Med Biol Illustr. 1976;26:139-144.
2. Gilchrest BA, Fitzpatrick TB, Anderson RR, Parrish JA. Localization of melanin pigmentation in the skin with Wood's lamp. Br J Dermatol. 1977;96:245-248.
3. Pagnoni A, Kligman AM. Ultraviolet photography to identify early photodamage in young children. Br J Dermatol. 1997;137:321-322.
4. Fulton JE Jr. Utilizing the ultraviolet (UV detect) camera to enhance the appearance of photodamage and other skin conditions. Dermatol Surg. 1997;23:163-169.
5. Hainer BL. Dermatophyte infections. Am Fam Physician. 2003; 67:101-108.
6. Caplan RM. Medical uses of the Wood's lump. JAMA. 1967;202: 1035-1038.
7. al-Gazali LI, Arthur RJ, Lamb JT, et al. Diagnostic and counselling difficulties using a fully comprehensive screening protocol for families at risk for tuberous sclerosis. J Med Genet. 1989;26:694-703.
8. Baraitser M, Patton MA. Reduced penetrance in tuberous sclerosis. J Med Genet. 1985;22:29-31.
9. Hempling SM. The applications of ultraviolet photography in clinical forensic medicine. Med Sci Law. 1981;21:215-222.
10. Wallace KL, Surchard JR, Curry SC, Reagan C. Diagnostic use of physicians detection of urine fluorescence in a simulated ingestion of sodium fluorescein containing antifreeze. Ann Emerg Med. 2001;38:49-54.
11. Santucci KA, Nelson DG, McQuillen KK, Duffy SJ, Linakis JG. Wood's lamp utility in the identification of semen. Pediatrics. 1999;104:1342-1344.
12. Gabby T, Winkleby MA, Boyce WT, Fisher DL, Lancaster A, Sensabaugh GF. Sexual abuse of children: the detection of semen on skin. Am J Dis Child. 1992;146:700-703.
13. Pang CY, Neligan P, Nakatsuka T, Sasaki GH. Assessment of the fluorescein dye test for prediction of skin flap viability in pigs. J Surg Res. 1986;41:173-181.
14. Bailey N. Blacklight photography of the eye. Contacto. 1961;5:91-96.
15. Rutherford A. Ultra-violet fluorescence photography in ophthalmology. Med Biol Illustr. 1973;23:204-205.
16. Molteno AC, Wynn-Williams G, Every SG, Bevin TH. Photography of the living human cornea in ultraviolet light. Australas Phys Eng Sci Med. 2004;27:22-24.
17. Lunnon RJ. Ultraviolet photography. In: Williams R, ed. Medical Photography Study Guide. London, UK: MTP Press Limited; 1984: 225-233.
18. Parrish JA, Urbach F, Pitts DG. UV-A: Biological Effects of Ultraviolet Radiation with Emphasis on Human Responses to Longwave Ultraviolet. New York, NY: Plenum Press; 1978:7-35.
19. Hansell P. Ultraviolet and fluorescence recording. In: Engel CE, ed. Photography for the Scientist. London, UK: Academic Press; 1968: 363-383.
20. Nieuwenhuis G. Lens focus shift required for reflected ultraviolet and infrared photography. J Biol Photogr. 1991;59:17-20.
21. McMullan RF. Photography of the cornea irradiated with UVR (thesis). Dunedin, New Zealand: University of Otago; 1991.
22. Williams RW, Williams G. Reflected Ultraviolet Photography. May 2002. Available at http://www.msp.rmit.edu.au/Article_01/04.html. Accessed October 29, 2003.
23. Kinsey VE. Spectral transmission of the eye to ultraviolet radiations. Arch Ophthalmol. 1948;39:508-513.
24. Boettner E, Wolter J. Transmission of the ocular media. Invest Ophthalmol. 1962;1:776-783.
25. Michalos P, Avila EN, Florakis GJ, Hersh PS. Do human tears absorb ultraviolet light? CLAO J. 1994;20:192-193.
26. Kolozsvari L, Nogradi A, Hopp B, Bor Z. UV absorbance of the human cornea in the 240 nm to 400 nm range. Invest Ophthalmol Vis Sci. 2002;43:2165-2168.
27. Cogan DG, Kinsey VE. Action spectrum of keratitis produced by ultraviolet radiation. Arch Ophthalmol. 1946;35:670-677.
28. Bachem A. Ophthalmic ultraviolet action spectra. Am J Ophthalmol. 1956;41:969-975.
29. Yamanashi BS, Hacker H, Klintworth GK. Wavelength dependence and kinetics of UV-induced free radical formation in the human cornea and lens. Photochem Photobiol. 1979;30:391-395.
30. IRPA/INIRC Guidelines. Proposed change to the IRPA 1985 guidelines on limits of exposure to ultraviolet radiation. Health Phys. 1989;56:971-972.
31. ICNIRP Statement. Guidelines on UV radiation exposure limits. Health Phys. 1996;71:978.
32. Iwamoto T, DeVoe AG. Electron microscopical study of the Fleischer ring. Arch Ophthalmol. 1976;94:1579-1584.
33. Bron AJ. Vortex patterns of the corneal epithelium. Trans Ophthalmol Soc UK. 1973;93:455-472.
34. May ME, Fish WW. The UV and visible spectral properties of ferritin. Arch Biochem Biophys. 1978;190:720-725.
35. Rose GE, Lavin MJ. The Hudson-Stahli line III: observations on morphology, a critical review of aetiology and a unified theory for the formation of iron lines of the corneal epithelium. Eye. 1987; 1:475-479.
36. Assil KK, Quantock AJ, Barrett AM, Schanzlin DJ. Corneal iron lines associated with the intrastromal corneal ring. Am J Ophthalmol. 1993;116:350-356.
37. Lüllman H, Lüllman-Rauch R, Wassermann O. Lipidosis induced by amphiphilic cationic drugs. Biochem Pharmacol. 1978;27:1103-1108.
38. UV-Nikkor 105 mm f/4.5: Instruction Manual. Tokyo: Nikon Corp., 1985.
39. Ilford Fact Sheet: XP2 Super. January 2001. Available at http://www.ilford.com/html/us_english/pdf/XP2SGB_QX.pdf. Accessed 12 May 2003.
40. Barraquer-Somers E, Chan CC, Green WR. Corneal epithelial iron deposition. Ophthalmology. 1983;90:729-734.
41. Klang G. Measurement and studies of the fluorescence of the human lens in vivo. Acta Ophthalmol. 1948;31:1-152.
42. Lerman S. Human ultraviolet radiation cataracts. Ophthalmic Res. 1980;12:303-314.
43. Lerman S. An experimental and clinical evaluation of lens transparency and aging. J Gerontol. 1983;38:293-301.
44. Lerman S, Borkman R. Spectroscopic evaluation and classification of the normal, aging and cataractous lens. Ophthalmic Res. 1976; 8:335-353.
45. Kurzel RB, Wolbarsht M, Yamanashi BS, Staton GW, Borkman RF. Tryptophan excited states and cataracts in the human lens. Nature. 1973;241:132-133.
46. Laube T, Apel H, Koch HR. Ultraviolet radiation absorption of intraocular lenses. Ophthalmology. 2004;111:880-885.
47. Norn MS. Hudson-Stahli's line of cornea. I. Incidence and morphology. Acta Ophthalmol. 1968;46:106-118.
48. Norn MS. Hudson-Stahli's iron line in the cornea. Occurrence in 1968 and 1988. Acta Ophthalmol. 1990;68:339-340.
49. Rose GE, Lavin MJ. The Hudson-Stahli line. I: An epidemiologic study. Eye. 1987;1:466-470.
50. Gass JD. The iron lines of the superficial cornea. Arch Ophthalmol. 1964;71:345-358.
51. Klyce SD, Beuerman RW. Structure and function of the cornea. In: Kaufman HE, Barron BA, McDonald MB, Waltman SR, eds. The Cornea. New York, NY: Churchill Livingstone; 1988:4.
52. Pepose JS, Ubels JL. The Cornea. In: WM Hart Jr, ed. Adler's Physiology of the Eye. Clinical Application. 9th Ed. St Louis; Mosby Year Book; 1992:29.
53. Schwab IR, Epstein RJ, Harris DJ, Pflugfelder SC, Wilhelmus KR, eds. External Disease and Cornea: Basic and Clinical Science Course. Section 8. San Francisco, CA: American Academy of Ophthalmology; 1997:246.
54. Duke-Elder S, Leigh AG. Diseases of the Outer Eye. Part 2. London: Henry Kimpton; 1965:985.
55. Duke-Elder S ed. System of Ophthalmology; vol 8, part 2.
56. Ultraviolet and visible absorption spectrophotometry. In: British Pharmacopoeia 2001. Vol 2. London: The Stationary Office; 2001; Appendix II B A133.
57. Lemp MA, Mathers WD. Corneal epithelial cell movement in humans. Eye. 1989;3:438-445.
58. Doane MG. Interactions of eyelids and tears in corneal wetting and the dynamics of the normal human eyeblink. Am J Ophthalmol. 1980;89:507-516.
59. Thoft RA, Friend J. The X,Y,Z hypothesis of corneal epithelial maintenance. Invest Ophthalmol Vis Sci. 1983;24:1442-1443.
60. Lavker RM, Sun TT. Epithelial stem cells: the eye provides a vision. Eye. 2003;17:937-942.
61. Dua HS, Forrester JV. The corneoscleral limbus in human corneal epithelial wound healing. Am J Ophthalmol. 1990;110: 646-656.
62. Dua HS, Singh A, Gomes JA, Laibson PR, Donoso LA, Tyagi S. Vortex or whorl formation of cultured human corneal epithelial cells induced by magnetic fields. Eye. 1996;10:447-450.
63. Nagasaki T, Zhao J. Centripetal movement of corneal epithelial cells in the normal adult mouse. Invest Ophthalmol Vis Sci. 2003; 44:558-566.
64. Cai CX, Birk DE, Linsenmayer TF. Nuclear ferritin protects DNA from UV damage in corneal epithelial cells. Mol Biol Cell. 1998;9: 1037-1051.
65. Applegate LA, Scaletta C, Panizzon R, Frenk E. Evidence that ferritin is UV inducible in human skin: part of a putative defense mechanism. J Invest Dermatol. 1998;111:159-163.
66. Inoue S, Spring KR. Solid-state detectors and cameras. In: Video Microscopy: The Fundamentals. 2nd ed. New Yor: Plenum Press; 1997:273-326.