Economic evaluation of ondansetron vs dimenhydrinate for prevention of postoperative vomiting in children undergoing strabismus surgery

Paediatric Anaesthesia

Volumn 15, Issue 9, 2005, Pages 755-761

  Piwko, Charles ^a,b   Lasry, Arielle ^a   Alanezi, Khaled ^a   Coyte, Peter C ^a,c   Ungar, Wendy J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c CANADIAN INSTITUTES OF HEALTH RESEARCH   (Canada)

Author keywords

Cost effectiveness; Dimenhydrinate; Ondansetron; Postoperative vomiting

Indexed keywords

ANESTHETIC AGENT; DIMENHYDRINATE; ONDANSETRON; ANTIEMETIC AGENT;

CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; COST CONSEQUENCE ANALYSIS; COST EFFECTIVENESS ANALYSIS; DRUG COST; DRUG EFFICACY; ECONOMIC EVALUATION; HEALTH CARE COST; HUMAN; LENGTH OF STAY; PEDIATRIC ANESTHESIA; PILOT STUDY; POSTANESTHESIA CARE; POSTOPERATIVE VOMITING; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; STRABISMUS; STUDENT T TEST; ARTICLE; CANADA; COST BENEFIT ANALYSIS; ECONOMICS; FEMALE; HEALTH CARE PERSONNEL; MALE; POSTOPERATIVE NAUSEA AND VOMITING; PRESCHOOL CHILD;

ANTIEMETICS; CHILD; CHILD, PRESCHOOL; COST-BENEFIT ANALYSIS; DRUG COSTS; FEMALE; HEALTH PERSONNEL; HUMANS; LENGTH OF STAY; MALE; ONDANSETRON; ONTARIO; PILOT PROJECTS; POSTOPERATIVE NAUSEA AND VOMITING; RETROSPECTIVE STUDIES; STRABISMUS;

EID: 32944462493     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2004.01528.x     Document Type: Review

References (21)

1. Tramer MR. A rational approach to the control of postoperative nausea and vomiting: evidence from systematic reviews. Part I. Efficacy and harm of antiemetic interventions and methodological issues. Acta Anaesth Scand 2001 45 : 4 13.
2. Glaxo Wellcome Inc. Zofran Postoperative Nausea and Vomiting. Therapeutic Review Monograph. Mississauga : GlaxoWellcome, 1996 DF, Carr AS, Sikich N et al. Dimenhydrinate decreases vomiting after strabismus surgery in children. Anesth Analg 1996 82 : 728 731.
3. Carr AS, Splinter WM, Bevan J et al. Ondansetron reduces postoperative vomiting in pediatric strabismus surgery. Anesthesiology 1994 81 : 3A.
4. Shende D, Bharti N, Kathirvel S et al. Combination of droperidol and ondansetron reduces PONV after pediatric strabismus surgery more than single drug therapy. Acta Anaesth Scand 2001 45 : 756 760.
5. Welters ID, Menges T, Graf M et al. Reduction of postoperative nausea and vomiting by dimenhydrinate suppositories after strabismus surgery in children. Anesth Analg 2000 90 : 311 314.
6. Bowhay AR, May HA, Rudnicka AR et al. A randomized controlled trial of the antiemetic effect of three doses of ondansetron after strabismus surgery in children. Paediatr Anaesth 2001 11 : 215 221.
7. Lerman J. Surgical and patient factors involved in postoperative nausea and vomiting. Brit J Anaesth 1992 69 (Suppl. 1 24S 32S.
8. Abramowitz MD, Oh TH, Epstein BS. The antiemetic effect of droperidol following outpatient strabismus surgery in children. Anesthesiology 1983 59 : 579 583.
9. Blanc VF, Ruest P, Milot J et al. Antiemetic prophylaxis with promethazin or droperidol in pediatric strabismus surgery. Can J Anaesth 1991 38 : 54 60.
10. Tramer MR, Reynolds DJM, Moore RA et al. When placebo controlled trials are essential and equivalence trials are inadequate. Br Med J 1998 317 : 875 880.
11. Kranke P, Morin AM, Roewer N et al. Dimenhydrinate for prophylaxis of postoperative nausea and vomiting: a meta-analysis of randomized controlled trials. Acta Anaesth Scand 2002 46 : 238 244.
12. Sennaraj OB, Shende D, Sadhasivam S et al. Management of post-strabismus nausea and vomiting in children using ondansetron: a value-based comparison of outcomes. Br J Anaesth 2002 89 : 473 478.
13. Sadhasivam S, Redd S. Unanticipated hospital admission, post discharge morbidities and emergency room visits following pediatric ambulatory anesthesia. Anesthesiology 2002 96 : A37.
14. Rose JB, Martin TM, Corddry DH et al. Ondansetron reduces the incidence and severity of poststrabismus repair vomiting in children. Anesth Analg 1994 79 : 486 489.
15. Madan R, Perumal T, Subramaniam K et al. Effect of timing of ondansetron administration on incidence of postoperative vomiting in pediatric strabismus surgery. Anaesth Int Care 2000 28 : 27 30.
16. Shende D, Mandal NG. Efficacy of ondansetron and metoclopramide for preventing postoperative emesis following strabismus surgery in children. Anaesthesia 1997 52 : 489 500.
17. Hamid SK, Selby IR, Sikich N et al. Vomiting after adenotonsillectomy in children: a comparison of ondansetron, dimenhydrinate and placebo. Anesth Analg 1998 86 : 496 500.
18. McCall JE, Stubbs K, Saylors S et al. The search for cost-effective prevention of postoperative nausea and vomiting in the child undergoing reconstructive burn surgery: ondansetron versus dimenhydrinate. J Burn Care Rehabil 1999 20 : 309 315.
19. Watcha MF, Smith I. Cost-effectiveness analysis of antiemetic therapy for ambulatory surgery. J Clin Anesth 1994 6 : 370 377.
20. Olutoye O, Jantzen EC, Alexis R. A comparison of the costs and efficacy of ondansetron and dolasetron in the prophylaxis of postoperative vomiting in pediatric patients undergoing ambulatory surgery. Anesth Analg 2003 97 : 390 396.
21. Fisher DM. The big little problem of postoperative nausea and vomiting: so we know the answer yet Anesthesiology 1997 87 : 1271 1273.