Antimicrobial resistance of Haemophilus influenzae isolated from the nasopharynx of Japanese children with acute otitis media

Acta Oto-Laryngologica

Volumn 126, Issue 3, 2006, Pages 240-247

  Hotomi, Muneki ^a   Fujihara, Keiji ^a   Sakai, Akihiro ^a   Billal, Dewan S ^a   Shimada, Jun ^a   Suzumoto, Masaki ^a   Yamanaka, Noboru ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

lactamase non producing ampicillin resistant Haemophilus influenzae; Acute otitis media; Nasopharynx; Polymerase chain reaction

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; BETA LACTAMASE; CEFACLOR; CEFCAPENE; CEFDINIR; CEFDITOREN; CEFPODOXIME; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 3; UNCLASSIFIED DRUG;

ACUTE OTITIS MEDIA; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; DILUTION; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENOTYPE; GRAM NEGATIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; HUMAN; MICROBROTH DILUTION; MULTIDRUG RESISTANCE; NASOPHARYNX; NONHUMAN; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL;

ACUTE DISEASE; AMPICILLIN RESISTANCE; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BETA-LACTAMASES; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, BACTERIAL; FEMALE; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; JAPAN; MALE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NASOPHARYNX; OTITIS MEDIA; OTITIS MEDIA WITH EFFUSION; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; SAMPLING STUDIES; SENSITIVITY AND SPECIFICITY;

EID: 32944459870     PISSN: 00016489     EISSN: None     Source Type: Journal    
DOI: 10.1080/00016480500314287     Document Type: Article

References (27)

1. St Geme JW III. The pathogenesis of non typeable Haemophilus influenzae otitis media. Vaccine 2000;19:S41-50.
2. Hotomi M, Yamanaka N, Samukawa T, Suzumot M, Sakai A, Shimada J, et al. Treatment and outcome of severe and non-severe acute otitis media. Eur J Pediatr 2005;164:3-8.
3. Samuelson A, Freijd A, Jonnasson J, Lindberg AA. Turnover of nonencapsulated Haemophilus influenzae in the nasopharynges of otitis-prone children. J Clin Microbiol 1995;33:2027-31.
4. Howard AJ, Dunkin KT, Millar GW. Nasopharyngeal carriage and antibiotic resistance of Haemophilus influenzae in healthy children. Epidemiol Infect 1988;100:193-203.
5. Foxwell AR, Kyd JM, Cripps AW. Nontypeable Haemophilus influenzae: pathogenesis and prevention. Microbiol Mol Biol Rev 1998;62:294-308.
6. Hotomi M, Yamanaka N, Shimada J, Ikeda Y, Faden H. Factors associated with clinical outcome in acute otitis media. Ann Otol Rhinol Laryngol 2004;113:846-52.
7. Reid AJ, Simpson IN, Harder PH, Aymes SGB. Ampicillin resistance in Haemophilus influenzae: identification of resistance mechanism. J Antimicrobiol Chemother 1987;20:645-56.
8. Vega R, Sadoff HL, Patterson MJ. Mechanism of ampicillin resistance in Haemophilus influenzae type B. Antimicrob Agents Chemother 1976;9:164-8.
9. Medeiros AA, Levesque R, Jacoby GA. An animal source for the ROB-1 beta-lactamase of Haemophilus influenzae type b. Antimicrob Agents Chemother 1986;29:212-5.
10. Mendelman PM, Chaffin DO, Kalaizoglou G. Penicillin binding proteins and ampicillin resistance in Haemophilus influenzae. J Antimicrob Chemother 1990;25:525-34.
11. Mendelman PM, Chaffin DO, Stull TL, Rubens CE, Mack KD, Selanser RK. Characterization of non-beta-lactamase-mediated ampicillin resistance in Haemophilus influenzae. Antimicrob Agents Chemother 1984;26:235-44.
12. Parr TR Jr, Bryan LE. Mechanism of resistance of an ampicillin-resistant, beta-lactamase-negative clinical isolate of Haemophilus influenzae type b to beta-lactam antibiotic. Antimicrob Agents Chemother 1984;25:747-53.
13. Clairoux N, Picard M, Brochu A, Rousseau N, Gourde P, Beauchamp D, et al. Molecular basis of non-β-lactamase-mediated resistance to β-lactam antibiotics in strains of Haemophilus influenzae. Antimicrob Agents Chemother 1992;36:1504-13.
14. Doern GV, Brueggemann AB, Pierce G Jr, Horry HP, Rauch A. Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: result of a national multicenter surveillance study. Antimicrob Agents Chemother 1997;41:292-7.
15. Seki H, Kasahara Y, Ohta K, Saikawa Y, Sumita R, Yachie A, et al. Increasing prevalence of ampicillin-resistant, non-lactamase-producing strains of Haemophilus influenzae in children in Japan. Chemotherapy 1999;45:15-21.
16. Hasegawa K, Yamamoto K, Chiba N, Kobayashi R, Nagai K, Jacobs MR, et al. Diversity of ampicillin-resistance genes in Haemophilus influenzae in Japan and United States. Microb Drug Resist 2003;9:39-46.
17. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing; eight informational supplements. Document M100-S8. Wayne, PA: NCCLS; 1998. p.18.
18. Ubukata K, Shibasaki Y, Yamamota K, Chiba N, Hasegawa K, Takeuchi Y, et al. Association of amino acid substitutions in penicillin binding protein 3 with β-lactam resistance in β-lactamase negative ampicillin-resistant Haemophilus influenzae. Antimicrob Agents Chemother 2001;45:1693-9.
19. Matic V, Bozdogan B, Jacob MR, Ubukata K, Appelbaum PC. Contribution of β-lactamase and PBP amino acid substitution to amoxicillin/clavulanate resistance in β-lactamase-positive amoxicillin-resistant Haemophilus influenzae. J Antimicrob Chemother 2003;52:1018-21.
20. Thomas WJ, McReynolds JW, Mock CR, Bailey DW. Ampicillin-resistant Haemophilus influenzae meningitis. Lancet 1974;i:313.
21. Doern GV, Jorgensen JH, Thornsbery C, Preston DA, and the H. influenzae surveillance group. Prevalence of antimicrobial resistance among clinical isolates of H. influenzae: a collaborative study. Diagn Microbiol Infect Dis 1986;4:95-107.
22. Doern GV, Jorgensen JH, Thornsbery C, Preston DA, Tubert T, Redding JS, et al. National collaborative study of prevalence of antimicrobial resistance among clinical isolates of Haemophilus influenzae. Antimicrob Agents Chemother 1988;32:180-5.
23. Fluit AC, Florijn A, Verhoef J, Milatovic D. Susceptibility of European beta-lactamase-positive and -negative Haemophilus influenzae isolates from the periods 1997/1998 and 2002/ 2003. J Antimicrob Chemother 2005;56:133-8.
24. Suzuki K, Nishimura T, Baba S. Current status of bacterial resistance in the otolaryngology field: results from the second national wide survey in Japan. J Infect Chemother 2003;9:46-52.
25. Hasegawa K, Chiba N, Kobayashi R, Murayama SY, Iwata S, Sunakawa K, et al. Rapidly increasing prevalence of beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae type b in patients with meningitis. Antimicrob Agents Chemother 2004;48:1509-14.
26. Kaczmarek FS, Gootz TD, Dib-Hajj F, Shang W, Hallowell S, Cronan M. Genetic and molecular characterization of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillin. Antimicrob Agents Chemother 2004;48:1630-9.
27. Brook I, Gober AE. Antimicrobial resistance in the nasopharyngeal flora of children with acute otitis media and otitis media recurring after amoxicillin therapy. J Med Microbiol 2005;54:83-5.