In vitro susceptibility of macrophages to porcine reproductive and respiratory syndrome virus varies between genetically diverse lines of pigs

Viral Immunology

Volumn 18, Issue 3, 2005, Pages 506-512

  Vincent, A L ^a   Thacker, B J ^a   Halbur, P G ^a   Rothschild, M J ^a   Thacker, E L ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIVIRUS; ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; GENETIC VARIABILITY; INFECTION SENSITIVITY; MACROPHAGE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; VIRUS REPLICATION; ANIMAL; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PATHOGENICITY; SPECIES DIFFERENCE; VIROLOGY; VIRUS INFECTION;

ANIMALIA; ARTERIVIRUS; PIERIS BRASSICAE; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SUS SCROFA;

VIRUS RNA;

ANIMALS; BASE SEQUENCE; FLOW CYTOMETRY; MACROPHAGES; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SPECIES SPECIFICITY; SUS SCROFA;

EID: 32944456975     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2005.18.506     Document Type: Article

References (23)

1. Benfield, D.A., E. Nelson, J.E. Collins, L. Harris, S.M. Goyal, D. Robison, W.T. Christianson, R.B. Morrison, D. Gorcyca, and D. Chladek. 1992. Characterization of swine infertility and respiratory syndrome (SIRS) virus (isolate ATCC VR-2332). J. Vet. Diagn. Invest. 4:127-133.
2. Collins, J.E., D.A. Benfield, W.T. Christianson, L. Harris, J.C. Hennings, D.P. Shaw, S.M. Goyal, S. McCullough, R.B. Morrison, H.S. Joo, et al. 1992. Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs. J. Vet. Diagn. Invest. 4:117-126.
3. Duan, X., H.J. Nauwynck, H.W. Favoreel, and M.B. Pensaert. 1998. Identification of a putative receptor for porcine reproductive and respiratory syndrome virus on porcine alveolar macrophages. J. Virol. 72:4520-4523.
4. Duan, X., H.J. Nauwynck, and M.B. Pensaert. 1997. Effects of origin and state of differentiation and activation of monocytes/macrophages on their susceptibility to porcine reproductive and respiratory syndrome virus (PRRSV). Arch. Virol. 142:2483-2497.
5. Edfors-Lilja, I., E. Wattrang, L. Marklund, M. Moller, L. Andersson-Eklund, L. Andersson, and C. Fossum. 1998. Mapping quantitative trait loci for immune capacity in the pig. J. Immunol. 161:829-835.
6. Genovesi, E.V., R.C. Knudsen, D.J. Gerstner, D.M. Card, C.L. Martins, J.C. Quintero, and T.C. Whyard. 1989. In vitro induction of swine peripheral blood monocyte proliferation by the fibroblast-derived murine hematopoietic growth factor CSF-1. Vet. Immunol. Immunopathol. 23:223-244.
7. Gogolin-Ewens, K.J., E.N. Meeusen, P.C. Scott, T.E. Adams, and M.R. Brandon. 1990. Genetic selection for disease resistance and traits of economic importance in animal production. Rev. Sci. Tech. 9:865-896.
8. Halbur, P.G., P.S. Paul, M.L. Frey, J. Landgraf, K. Eernisse, X.J. Meng, M.A. Lum, J.J. Andrews, and J.A. Rathje. 1995. Comparison of the pathogenicity of two U.S. porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 32:648-660.
9. Halbur, P.G., P.S. Paul, X.J. Meng, M.A. Lum, J.J. Andrews, and J.A. Rathje. 1996. Comparative pathogenicity of nine U.S. porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrum-deprived pig model. J. Vet. Diagn. Invest. 8:11-20.
10. Halbur, P.G., M.F. Rothschild, B.J. Thacker, X.-J. Meng, P.S. Paul, and J.D. Bruna. 1998. Differences in susceptibility of Duroc, Hampshire, and Meishan pigs to infection with a high virulence strain (VR2385) of porcine reproductive and respiratory syndrome virus (PRRSV). J. Anim. Breeding Genet. 115:181-189.
11. Henryon, M., P. Berg, J. Jensen, and S. Andersen. 2001. Genetic variation for resistance to clinical and subclinical diseases exists in growing pigs. Anim. Sci. 73:375-387.
12. Labarque, G., S. Van Gucht, H. Nauwynck, K. Van Reeth, and M. Pensaert. 2003. Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines. Vet. Res. 34:249-260.
13. Molitor, T.W., J. Xiao, and C.S. Choi. 1996. PRRS virus infection of macrophages: regulation by maturation and activation state. Presented at the 27th Annual Meeting of the American Association of Swine Practice, Nashville, TN.
14. Nauwynck, H.J., X. Duan, H.W. Favoreel, P. Van Oostveldt, and M.B. Pensaert. 1999. Entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages via receptor-mediated endocytosis. J. Gen. Virol. 80:297-305.
15. Sirinarumitr, T., Y. Zhang, J.P. Kluge, P.G. Halbur, and P.S. Paul. 1998. A pneumo-virulent United States isolate of porcine reproductive and respiratory syndrome virus induces apoptosis in bystander cells both in vitro and in vivo. J. Gen. Virol. 79:2989-2995.
16. Thacker, E., P. Kitikoon, A. Vincent, K. Hipple, D. Nilubol, S. Yu, B. Janke, and B. Thacker. 2003. Influence of PRRSV infection on swine influenza vaccine efficacy. Presented at the 4th International Symposium on Emerging and Re-Emerging Pig Diseases, Rome.
17. Thacker, E.L., P.G. Halbur, P.S. Paul, and B.J. Thacker. 1998. Detection of intracellular porcine reproductive and respiratory syndrome virus nucleocapsid protein in porcine macrophages by flow cytometry. J. Vet. Diagn. Invest. 10:308-311.
18. Thacker, E.L., B.J. Thacker, T.F. Young, and P.G. Halbur. 2000. Effect of vaccination on the potentiation of porcine reproductive and respiratory syndrome virus (PRRSV)-induced pneumonia by Mycoplasma hyopneumoniae. Vaccine 18:1244-1252.
19. van der Waaij, E.H., P. Bijma, S.C. Bishop, and J.A. van Arendonk. 2002. Using genetic markers for disease resistance to improve production under constant infection pressure. J. Anim. Sci. 80:322-329.
20. Vanderheijden, N., P.L. Delputte, H.W. Favoreel, J. Vandekerckhove, J. Van Damme, P.A. van Woensel, and H.J. Nauwynck. 2003. Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages. J. Virol. 77:8207-8215.
21. Voicu, I.L., A. Silim, M. Morin, and M.A. Elazhary. 1994. Interaction of porcine reproductive and respiratory syndrome virus with swine monocytes. Vet. Rec. 134:422-423.
22. Warner, C.M., D.L. Meeker, and M.F. Rothschild. 1987. Genetic control of immune responsiveness: a review of its use as a tool for selection for disease resistance. J. Anim. Sci. 64:394-406.
23. Weingartl, H.M., M. Sahara, J. Pasick, E. van Moorlehem, and L. Babiuk. 2002. Continuous porcine cell lines developed from alveolar macrophages: partial characterization and virus susceptibility. J. Virol. Methods 104:203-216.