The promises and potential pitfalls of organ preservation for locally advanced rectal cancer

Annals of Surgical Oncology

Volumn 13, Issue 3, 2006, Pages 288-290

  Crane, Christopher H ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; CORRELATION ANALYSIS; ECHOGRAPHY; EDITORIAL; HUMAN; METASTASIS; ORGAN PRESERVATION; OUTCOME ASSESSMENT; PHYSICAL EXAMINATION; POSITRON EMISSION TOMOGRAPHY; PREDICTION; RADIOSENSITIVITY; RECTUM CANCER; RISK ASSESSMENT; SURGICAL TECHNIQUE; SURVIVAL RATE;

ANAL CANAL; HUMANS; LYMPHATIC METASTASIS; NEOADJUVANT THERAPY; PROGNOSIS; RECTAL NEOPLASMS; RECTUM;

EID: 32844475367     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1245/ASO.2006.09.908     Document Type: Editorial

References (11)

1. Nigro ND, Vaitkevicius VK, Considine B Jr. Combined therapy for cancer of the anal canal: a preliminary report. Dis Colon Rectum 1974; 17:354-6.
2. Hung A, Crane C, Delclos M, et al. Cisplatin-based combined modality therapy for anal carcinoma: a wider therapeutic index. Cancer 2003; 97:1195-202.
3. Flam M, John M, Pajak TF, et al. Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. J Clin Oncol 1996; 14:2527-39.
4. Kim CJ, Yeatman TJ, Coppola D, et al. Local excision of T2 and T3 rectal cancers after downstaging chemoradiation. Ann Surg 2001; 234:352-8; discussion 358-9.
5. Mohiuddin M, Marks G, Bannon J. High-dose preoperative radiation and full thickness local excision: a new option for selected T3 distal rectal cancers. Int J Radiat Oncol Biol Phys 1994; 30:845-9.
6. Bonnen M, Crane C, Vauthey J-N, et al. Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients. Int J Radiat Oncol Biol Phys 2004; 60:1098-105.
7. Schell SR, Zlotecki RA, Mendenhall WM, et al. Transanal excision of locally advanced rectal cancers downstaged using neoadjuvant chemoradiotherapy. J Am Coll Surg 2002; 194:584-90; discussion 590-1.
8. Habr-Gama A, Perez RO, Nadalin W, et al. Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results. Ann Surg 2004; 240:711-7.
9. Tulchinsky H, Rabau M, Shemueli E, et al. Can rectal cancers with pathologic T0 after neoadjuvant chemoradiation (ypT0) be treated by transanal excision alone? Ann Surg Oncol (in press).
10. Bedrosian I, Rodriguez-Bigas MA, Feig B, et al. Predicting the node-negative mesorectum after preoperative chemoradiation for locally advanced rectal carcinoma. J Gastrointest Surg 2004; 8:56-62.
11. Crane C, Myerson R, Mendenhall W, et al. Complete pathologic response in the primary rectal tumor after (chemo)radiation correlates with negative mesorectal lymph nodes in cN0 patients: implications for organ preserving strategies (abstract 329). Radiother Oncol 2004; 73:149.