Increased acute GvHD and higher transplant-related mortality in non-caucasians undergoing standard sibling allogeneic stem cell transplantation

Bone Marrow Transplantation

Volumn 37, Issue 4, 2006, Pages 419-423

  Karanth, M ^a   Begum, G ^b   Cook, M ^a   Lawson, S ^c   Porter, C ^a   Lister, N ^a   Gray, J ^a   Darbyshire, P ^c   Craddock, C ^a   Mahendra, Prem ^a  

^a UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

aGvHD; Alogenic SCT; Ethnicity; Non Caucasians; TRM

Indexed keywords

ACICLOVIR; BUSULFAN; CIPROFLOXACIN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; FLUCONAZOLE; FLUDARABINE; MELPHALAN; METHOTREXATE; METRONIDAZOLE;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ADOLESCENT; ADULT; ALLOGENEIC STEM CELL TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; CAUCASIAN; CHILD; CHRONIC GRAFT VERSUS HOST DISEASE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DEATH; FANCONI ANEMIA; FEMALE; FOLLOW UP; GRAFT SURVIVAL; HUMAN; INFECTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; NUTRITIONAL STATUS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SIBLING; SOCIOECONOMICS; TREATMENT OUTCOME; VIRUS REACTIVATION;

ACUTE DISEASE; ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; GRAFT VS HOST DISEASE; GREAT BRITAIN; HEMATOLOGIC DISEASES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; RECURRENCE; RETROSPECTIVE STUDIES; SIBLINGS; SURVIVAL RATE; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 32844472527     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705260     Document Type: Article

References (18)

1. Ayanian JZ, Cleary PD, Weissman JS, Epstein AM. The effect of patients' preferences on racial differences in access to renal transplantation. N Eng J Med 1999; 341: 1661-1669.
2. Pollock BH, DeBaun RM, Camitta BM, Shuster JJ, Ravindranath Y, Pullen DJ et al. Racial differences in survival of childhood B-precursor acute lymphoblastic leukaemia: A Paediatric Oncology Group Study. J Clin Oncol 2000; 18: 813-823.
3. Bhatia S, Sather HN, Heerema NA, Trigg ME, Gaynon PS, Robison LL. Racial and ethnic differences in survival of children with acute lymphoblastic leukemia. Blood 2002; 100: 1957-1964.
4. Dayal HH, Chiu C. Factors associated with racial difference in survival for prostatic carcinoma. J Chronic Dis 1982; 35: 553-560.
5. Gilliland FD, Hunt WC, Key CR. Ethnic variation in prostate cancer survival in New Mexico. Cancer Epidemiol Biomarkers Prev 1996; 5: 247-251.
6. Eley JQ, Hill HA, Chen VW, Austin DF, Wesley MN, Muss HB et al. Racial differences in survival from breast cancer: Results of the National Cancer Institute Black/White Cancer Survival Study. JAMA 1994; 272: 947-954.
7. Baquet CR, Commiskey P. Socioeconomic factors and breast carcinoma in multicultural women. Cancer 2000; 88: 1256-1264.
8. O'Malley CD, Le GM, Glaser SL, Shema SJ, West DW. Socioeconomic status and breast carcinoma survival in four racial/ethnic groups: A population-based study. Cancer 2003; 97: 1303-1311.
9. Sekeres MA, Peterson G, Dodge RK, Mayer RJ, Moore JO, Lee EJ et al. Differences in prognostic factors and outcomes in African-Americans and Caucasians with acute myeloid leukemia. Blood 2004; 103: 4036-4042.
10. Schmiegelow K, Schroder H, Gustgafsson G, Kristinsson J, Glomstein A, Salmi T et al. Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy: Nordic Society for Pediatric Hematology and Oncology. J Clin Oncol 1995; 13: 345-351.
11. Peto R, Pike MC, Armitage P. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br J Cancer 1977; 35: 1-39.
12. Kaplan EJ, Meier P. Non parametric estimation from incomplete observations. J Stat Assoc 1958; 53: 457-481.
13. Solano C, Martinez C, Burnet S, Tomas JF, Urbano-Ispizua A, Ojeda E et al. Chronic graft-versus-host disease after allogeneic peripheral blood progenitor cell or bone marrow transplantation from matched related donors. A case-control study. Spanish Group of Allo-PBT. Bone Marrow Transplant 1998; 22: 1129-1135.
14. Scott MA, Ghandhi MK, Jestice HK, Mahendra P, Bass G, Marcus RE. A trend towards an increased incidence of chronic graft-versus-disease following allogeneic peripheral blood progenitor cell transplantation: A case controlled study. Bone Marrow Transplant 1998; 22: 273-276.
15. Serna DS, Lee SJ, Zhang M, Baker KS, Eapen M, Horowitz MM et al. Trends in survival rates after allogeneic hematopoietic stem-cell transplantation for acute and chronic leukemia by ethnicity in the United States and Canada. J Clin Oncol 2003; 21: 3754-3760.
16. Piu CH, Boyett JM, Hancock ML, Pratt CB, Meyer WH, Crist WM. Outcome of treatment for childhood cancer in black as compared with white children. JAMA 1995; 273: 633-637.
17. Mielcarek M, Gooley T, Martin PJ, Chauncey TR, Young BA, Storb R et al. Survival after hematopoietic cell transplantation according to ethnic background. Blood #841 2003; 102: 239a.
18. Oh H, Loberiza Jr FR, Zhang M, Ringden O, Akiyama H, Asai T et al. Comparison of graft-vs-host disease and survival after HLA identical sibling bone marrow transplantation in different ethnic populations. Blood 2005; 105: 1408-1416.