Profile likelihood-based confidence intervals using Monte Carlo integration for population pharmacokinetic parameters

Journal of Biopharmaceutical Statistics

Volumn 16, Issue 2, 2006, Pages 193-205

  Funatogawa, Takashi ^a,b   Funatogawa, Ikuko ^c   Yafune, Akifumi ^d  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Clinic Sendagaya   (Japan)

Author keywords

Confidence interval; Monte Carlo integration; Nonlinear mixed effects model; Population pharmacokinetics; Profile likelihood

Indexed keywords

ERYTHROPOIETIN;

ARTICLE; CONCENTRATION (PARAMETERS); CONFIDENCE INTERVAL; MONTE CARLO METHOD; PRIORITY JOURNAL; SIMULATION; STATISTICAL ANALYSIS;

COMPUTER SIMULATION; CONFIDENCE INTERVALS; ERYTHROPOIETIN, RECOMBINANT; HUMANS; LIKELIHOOD FUNCTIONS; MODELS, STATISTICAL; MONTE CARLO METHOD; PHARMACOKINETICS;

EID: 32844457874     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543400500508861     Document Type: Article

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