Infections in a pediatric patient cohort with acute lymphoblastic leukemia during the entire course of treatment

Supportive Care in Cancer

Volumn 14, Issue 3, 2006, Pages 277-284

  Katsimpardi, Katerina ^a   Papadakis, Vassilios ^a   Pangalis, Anastasia ^a   Parcharidou, Agapi ^a   Panagiotou, John P ^a   Soutis, Michael ^a   Papandreou, Evangelos ^a   Polychronopoulou, Sophia ^a   Haidas, Stavros ^a  

^a AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

Author keywords

Acute lymphoblastic leukemia; Childhood; Infectious complications; Neutropenia; Varicella zoster virus

Indexed keywords

AMIKACIN; AMPHOTERICIN B LIPID COMPLEX; ASPARAGINASE; CEFTAZIDIME; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; MERCAPTOPURINE; METHOTREXATE; MICONAZOLE; NYSTATIN; PENTAMIDINE; PREDNISOLONE; TIOGUANINE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE OTITIS MEDIA; ADOLESCENT; AEROMONAS; ANTIBIOTIC PROPHYLAXIS; APPENDICITIS; ARTICLE; BACTEREMIA; BLOOD CULTURE; BRONCHOPNEUMONIA; CANCER PATIENT; CATHETER INFECTION; CENTRAL NERVOUS SYSTEM INFECTION; CHICKENPOX; CHILD; CHILDHOOD CANCER; CLINICAL PROTOCOL; COHORT ANALYSIS; CONJUNCTIVITIS; CONTROLLED STUDY; CORYNEBACTERIUM; COXSACKIE VIRUS; ENTEROBACTER; EPSTEIN BARR VIRUS; EYE INFECTION; FEMALE; FOLLICULITIS; GASTROINTESTINAL INFECTION; GRAM NEGATIVE SEPSIS; HELICOBACTER PYLORI; HERPES SIMPLEX; HERPES SIMPLEX VIRUS; HERPES ZOSTER; HUMAN; INFANT; INFECTION COMPLICATION; LARYNGITIS; LOBAR PNEUMONIA; LOWER RESPIRATORY TRACT INFECTION; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MEDICAL DOCUMENTATION; MUMPS; MYCOSIS; NEUTROPENIA; NEUTROPHIL COUNT; PARONYCHIA; PARVOVIRUS; PNEUMONIA; PRIORITY JOURNAL; PYODERMA; PYREXIA IDIOPATHICA; RETROSPECTIVE STUDY; SINUSITIS; STAPHYLOCOCCUS; STOMATITIS; TONSILLITIS; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION; UROGENITAL TRACT INFECTION; VAGINITIS; VIRAL GASTROENTERITIS; VIRUS INFECTION; VIRUS MENINGITIS;

ACUTE DISEASE; ADOLESCENT; ANTINEOPLASTIC AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; GERMANY; HUMANS; INFANT; INFECTION; LEUKEMIA, LYMPHOCYTIC; MALE; PEDIATRICS;

EID: 32644483147     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-005-0884-6     Document Type: Article

References (26)

1. Alexander SW, Walsh TJ, Freifeld AG, Pizzo PA (2002) Infectious complications in pediatric cancer patients. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology. Lippincot Williams & Wilkins, Philadelphia, pp 1239-1283
2. Aquino VM, Pappo A, Buchanan GR et al (1995) The changing epidemiology of bacteremia in neutropenic children with cancer. Pediatr Infect Dis J 14:140-143
3. Balfour HH Jr (1991) Varicella-zoster virus infections in the immunocompromised host. Natural history and treatment. Scand J Infect Dis Suppl 80:69-74
4. Bodey GP, Buckley M, Sathe YS, Freireich EJ (1996) Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 64:328-340
5. Donowitz GR, Maki DG, Crnich CJ et al (2001) Infections in the neutropenic patient - new views of an old problem. Hematology (Am Soc Hematol Educ Program) 113-139
6. Giamarellou H, Antoniadou A (2001) Infectious complications of febrile leukopenia. Infect Dis Clin North Am 15:457-482
7. Haidas S, Grafakos S, Ziva M et al (1984) Infections in leukemic children. Ann Clin Pediatr Univ Atheniensis 31:100-107
8. Hughes WT, Armstrong D, Bodey GP et al (1997) 1997 guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. Infectious Diseases Society of America. Clin Infect Dis 25:551-573
9. Karthaus M, Doellmann T, Klimasch T et al (2002) Central venous catheter infections in patients with acute leukemia. Chemotherapy 48:154-157
10. Kostaridou S, Polychronopoulou S, Psarra K et al (2004) Decrease of CD4+ and B-lymphocyte population is not associated with severe infectious complications in children with acute lymphoblastic leukemia during maintenance. Int J Hematol 80:354-360
11. Lex C, Korholz D, Kohlmuller B et al (2001) Infectious complications in children with acute lymphoblastic leukemia and T-cell lymphoma - a rationale for tailored supportive care. Support Care Cancer 9:514-521
12. Meir HM, Balawi IA, Meer HM et al (2001) Fever and granulocytopenia in children with acute lymphoblastic leukemia under induction therapy. Saudi Med J 22(5):423-427
13. Papadakis V, Panagiotou PI, Polychronopoulou S et al (2003) Results of childhood acute lymphoblastic leukemia treatment in Greek patients using a BFM-based protocol. Haema 6:208-216
14. Pizzo PA (1993) Management of fever in patients with cancer and treatment-induced neutropenia. N Engl J Med 328:1323-1332
15. Pizzo PA, Rubin M, Freifeld A, Walsh TJ (1991) The child with cancer and infection I. Empirical therapy for fever and neutropenia, and preventive strategies. J Paediatr 119:679-694
16. Pizzo PA, Rubin M, Freifeld A, Walsh TJ (1991) The child with cancer and infection II. Nonbacterial infections. J Paediatr 119:845-857
17. Polychronopoulou S, Panagiotou PI, Raftopoulou A et al (1994) Prevalence of Gram (+) microorganisms in septicemias in immunocompromised children. Paediatriki 17:75 (abstr)
18. Pui CH, Evans WE (1998) Acute lymphoblastic leukemia. N Engl J Med 339:605-615
19. Pui CH, Ribeiro RC (2003) International collaboration on childhood leukemia. Int J Hematol 78:383-389
20. Rackoff WR, Ge J, Sather HN, Cooper HA, Hutchinson RJ, Lange BJ (1999) Central venous catheter use and the risk of infection in children with acute lymphoblastic leukemia: a report from the Children's Cancer Group. J Pediatr Hematol/Oncol 21(4):260-267
21. Rahiala J, Perkkiö M, Riikonen P (1998) Infections occurring during the courses of anticancer chemotherapy in children with ALL. Pediatr Hematol Oncol 15:165-174
22. Schimpff SC (1993) Gram-negative bacteremia. Support Care Cancer 1:5-18
23. Schrappe M, Reiter A, Ludwig WD et al (2000) Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90.German-Austrian-Swiss ALL-BFM Study Group. Blood 95:3310-3322
24. Wehl G, Allerberger F, Heitger A et al (1999) Trends in infection morbidity in a pediatric oncology ward, 1986-1995. Med Pediatr Oncol 32:336-343
25. Wood DJ, Corbitt G (1985) Viral infections in childhood leukemia. J Infect Dis 152:266-273
26. Zinner SH (1999) Changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. Clin Infect Dis 29:490-494