Intramedullary spinal cord metastases from atypical small cell lung cancer: A case report and literature review

Cancer Investigation

Volumn 24, Issue 1, 2006, Pages 46-49

  Nikolaou, Maria ^a   Koumpou, Maria ^a   Mylonakis, Nicolaos ^a   Karabelis, Athanasios ^a   Pectasides, Dimitris ^a   Kosmas, Christos ^a  

^a METAXA CANCER HOSPITAL   (Greece)

Author keywords

Intramedullary spinal cord metastases; Small cell lung cancer

Indexed keywords

CARBOPLATIN; CISPLATIN; ETOPOSIDE; PACLITAXEL; STEROID; TOPOTECAN;

ADULT; AUTONOMIC DYSFUNCTION; BRAIN METASTASIS; BROWN SEQUARD SYNDROME; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER SURVIVAL; CASE REPORT; CAUSE OF DEATH; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL EXAMINATION; CLINICAL FEATURE; CONVALESCENCE; FEMALE; HUMAN; LUNG SMALL CELL CANCER; MEDICAL LITERATURE; MOTOR PERFORMANCE; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROGNOSIS; RADIODIAGNOSIS; REVIEW; SPINAL CORD COMPRESSION; SPINAL CORD METASTASIS; SPINAL CORD SURGERY; STEROID THERAPY; SURVIVAL TIME; THORACIC SPINE; THORACOSCOPY; TREATMENT FAILURE; TREATMENT OUTCOME;

BROWN-SEQUARD SYNDROME; CARCINOMA, SMALL CELL; FATAL OUTCOME; FEMALE; HUMANS; LUNG NEOPLASMS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; SPINAL CORD NEOPLASMS;

EID: 32644480433     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900500449686     Document Type: Review

References (34)

1. Potti, A.; Abdel-Raheem, M.; Levitt, R.; Schell, D.A.; Mehdi, S.A. Intramedullary spinal cord metastases (ISCM) and non-small cell lung carcinoma (NSCLC): clinical patterns, diagnosis and therapeutic considerations. Lung Cancer 2001, 31, 319-323.
2. Schiff, D.; O'Neill, B.P. Intramedullary spinal cord metastases: clinical features and treatment outcome. Neurology 1996, 47, 906-912.
3. Kosmas, C.; Koumpou, M.; Nikolaou, M.; Katselis, J.; et al. Intramedullary spinal cord metastases in breast cancer: report of four cases and review of the literature. J. Neurooncol. 2005, 71, 67-72.
4. Thomas, A.W.; Simon, S.R.; Evans, C. Intramedullary spinal cord metastases from epithelial ovarian carcinoma. Gynecol. Oncol. 1992, 44, 195-197.
5. Amin R. Intramedullary spinal cord metastasis from carcinoma of the cervix. Br. J. Radiol. 1999, 72, 89-91.
6. Honma, Y.; Kawakita, K.; Nagao, S. Intramedullary spinal cord and brain metastases from thyroid carcinoma detected 11 years after initial diagnosis-case report. Neurol. Med. Chir. (Tokyo) 1996, 36, 593-597.
7. Gose, K.; Imajo, Y.; Takimoto, S.; Ichiyanagi, A.; Oshitani, T.; Kimura, S.; Hiratsuka, J.; Ueda, N.; Yamaguchi, T. Two autopsy cases of intramedullary spinal cord metastasis. Gan. No. Rinsho. 1984, 30, 319-323.
8. Grem, J.L.; Burgess, J.; Trump, D.L. Clinical features and natural history of intramedullary spinal cord metastasis. Cancer 1985, 56, 2305-2314.
9. Murphy, K.C.; Feld, R.; Evans, W.K.; Shepherd, F.A.; Perrin, R.; Sima, A.A.; Poon, P.Y. Intramedullary spinal cord metastases from small cell carcinoma of the lung. J. Clin. Oncol. 1983, 1, 99-106.
10. Schwechheimer, K.; Lemminger, J.M. Intramedullary metastases: report of 4 cases and review of the literature. Clin. Neuropathol. 1985, 4, 28-37.
11. Wada, H.; Ieki, R.; Ota, T.; Iguchi, M.; Yuasa, K.; Okamura, T.; Karasawa, K.; Goto, H. Intramedullary spinal cord metastasis of lung adenocarcinoma causing Brown-Sequard Syndrome. Nihon. Kokyuki. Gakkai Zasshi 2001, 39, 590-594.
12. Aryan, H.E.; Farin, A.; Nakaji, P.; Imbesi, S.G.; Abshire, B.B. Intramedullary spinal cord metastasis of lung adenocarcinoma presenting as Brown-Sequard syndrome. Surg. Neurol. 2004, 61, 72-76.
13. Sculier, J.P.; Feld, R.; Evans, W.K.; DeBoer, G.; Shepherd, F.A.; Payne, D.G.; Pringle, J.F.; Yeoh, J.L.; Quirt, I.C.; Curtis, J.E. Neurologic disorders in patients with small cell lung cancer. Cancer 1987, 60, 2275-2283.
14. Okamoto, H.; Shinkai, T.; Motsuno, Y.; Saijo, N. Intradural parenchymal involvement in the spinal subarachnoid space associated with primary lung cancer. Cancer 1993, 72, 2583-2588.
15. Connolly, E.S. Jr.; Winfree, C.J.; McCormick, P.C.; Cruz, M.; Stein, B.M. Intramedullary spinal cord metastasis: report of three cases and review of the literature. Surg. Neurol. 1996, 46, 329-337.
16. Weissman, D.E.; Grossman, S.A. Simultaneous leptomeningeal and intramedullary spinal metastases in small cell lung carcinoma. Med. Pediatr. Oncol. 1986, 14, 54-56.
17. Puljik, S.; Batnitsky, S.; Yang, W.C.; Sclechter, M.M. Metastases to the medulla of the spinal cord: myelographic features. Radiology 1975, 117, 89-91.
18. Fredericks, R.K.; Elster, A.; Walker, F.O. Gadolinium-enhanced MRI: a superior technique for the diagnosis of intraspinal metastases. Neurology 1989, 39, 734-736.
19. Norman, M.D.; Adelstein, D.J.; Karlins, N.L. Intramedullary spinal cord metastasis: diagnostic and therapeutic considerations. Arch. Neurol. 1987, 44, 526-531.
20. Kalayci, M.; Cagavi, F.; Gul, S.; Yenidunya, S.; Acikgoz, B. Microsurgical resection of intramedullary spinal cord metastases of large cell lung cancer. Acta Neurochir (Wien) 2004, 146, 1347-1354.
21. Patchell, R.;Tibbs, P.A.; Regine, W.F.; Payne, R.; Saris, S.; Kryscio, R.J.; Young, B. A randomized trial of direct decompressive surgical resection in the treatment of spinal cord compression caused by metastasis. Proc. Am. Soc. Clin. Oncol. 2003; 22, 1 (Abstr. 2).
22. Hashizumi, Y., Hirano, A. Intramedullary spinal cord metastasis: pathologic findings in five autopsy cases. Acta. Neuropathol. 1983, 61, 214-218.
23. Findlay, J.M.; Bernstein, M.; Vanderlinden, R.G.; Resch, L. Microsurgical resection of solitary intramedullary spinal cord metastases. Neurosurgery 1987, 21, 911-915.
24. Tognetti, F.; Lanzino, G.; Calbucci, F. Metastases of the spinal cord from remote neoplasms. Study of five cases. Surg. Neurol. 1988, 30, 220-227.
25. Murate, T.; Hasegawa, T.; Hasegawa, Y.; Shimokata, K. A case report of small cell lung cancer with extrahepatic biliary obstruction and intramedullary spinal cord metastasis. Nihon Kokyuki Gakkai Zasshi 1989, 27, 513-517.
26. Aoki, H.; Fujimato, H.; Harada, K.; Tomonari, A.; Nakamura, Y.; Kanazawa, K.; Masuda, K.; Shinomiya, S.; Kawai, H. Intramedullary spinal cord metastasis from lung cancer presenting with paraparesis: an autopsied case. Tokushima J. Exp. Med. 1992, 39, 89-93.
27. Lorenzo, J.L.; Roquer, J.; Alameda, F.; Herraiz, J. Brown-Sequard syndrome secondary to intramedullary metastasis as the initial symptom of microcytic lung tumor. Med. Clin. 1996, 106, 199.
28. Markus, J.B. Magnetic resonance imaging of intramedullary spinal cord metastases. Clin. Imag. 1996, 20, 238-242.
29. Takatsugi, K.; Komuta, K.; Hosen, N.; Kitada, S.; Iida, S.; Nishihara, K.; Kimura, R.; Maeda, K.; Igarashi, T. Metastasis of small cell lung cancer to the parotid gland as the initial clinical manifestation, followed by metastases to the pituitary gland and lumbar spinal cord. Nihon Kokyuki Gakkai Zasshi 1998, 36, 246-250.
30. Ferroir, J.P.; Cadranel, J.; Khalil, A.; Lebreton, C.; Contant, S.; Milleron, B. Intramedullary metastases of bronchogenic carcinoma. Two cases. Rev. Neurol. (Paris) 1998, 154, 166-169.
31. Ito, K.; Sudo, A.; Imai, Y.; Yoshizawa, H.; Suzuki, E.; Arakawa, M. Intramedullary metastasis of small cell lung cancer. Nihon. Kokyuki. Gakkai Zasshi 1999, 37, 485-488.
32. Komori, T.; Delbeke, D. Leptomeningeal carcinomatosis and intramedullary spinal cord metastases from lung cancer: detection with FDG positron emission tomography. Clin. Nucl. Med. 2001, 26, 905-907.
33. Faillot, T.; Roujeau, T.; Dulou, R.; Blanc, J.L.; Chedru, F. Intramedullary spinal cord metastasis: is there a place for surgery? Case report and review of literature. Neurochirurgie 2002, 48, 533-536.
34. Tashima, M.; Ono, N.; Noguchi, T.; Ishikawa, H.; Kamakari, K.; Terada, Y. Two cases of intramedullary spinal cord metastasis of lung cancer detected with MRI. Nihon Kokyuki Gakkai Zasshi 2003, 41, 320-323.