Resistance to cassava mosaic disease in transgenic cassava expressing antisense RNAs targeting virus replication genes

Plant Biotechnology Journal

Volumn 3, Issue 4, 2005, Pages 385-397

  Zhang, Peng ^a   Vanderschuren, Hervé ^a   Fütterer, Johannes ^a   Gruissem, Wilhelm ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

African cassava mosaic virus; Cassava; Gene silencing; Genetically engineered virus resistance; Viral antisense RNAs

Indexed keywords

AFRICAN CASSAVA MOSAIC VIRUS; MANIHOT ESCULENTA;

EID: 32644445209     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/j.1467-7652.2005.00132.x     Document Type: Article

References (50)

1. Akano A.O. Dixon A.G.O. Mba C. Barrera E. Fregene M. ( 2002) Genetic mapping of a dominant gene conferring resistance to cassava mosaic disease. Theor. Appl. Genet. 105, 521 525.
2. Aragão F.J.L. Ribeiro S.G. Barros L.M.G. Brasileiro A.C.M. Maxwell D.P. Rech E.L. Faria J.C. ( 1998) Transgenic beans (Phaseolus vulgaris L.) engineered to express viral antisense RNAs show delayed and attenuated symptoms to bean golden mosaic geminivirus. Mol. Breed. 4, 491 499.
3. Asad S. Haris W.A.A. Bashir A. Zafar Y. Malik K.A. Malik N.N. Lichtenstein C.P. ( 2003) Transgenic tobacco expressing geminiviral RNAs is resistant to the serious viral pathogen causing cotton leaf curl disease. Arch. Virol. 148, 2341 2352.
4. Assaad F.F. Tucker K.L. Signer E.R. ( 1993) Epigenetic repeat-induced gene silencing (RIGS) in Arabidopsis. Plant Mol. Biol. 22, 1067 1085.
5. Aufsatz W. Mette M.F. van der Winden J. Matzke A.J. Matzke M. ( 2002) RNA-directed DNA methylation in Arabidopsis. Proc. Natl. Acad. Sci. USA, 99, 16 499 16 506.
6. Bejarano E.R. Lichtenstein C.P. ( 1994) Expression of TGMV antisense RNA in transgenic tobacco inhibits replication of BCTV but not ACMV geminiviruses. Plant Mol. Biol. 24, 241 248.
7. Bendahmane M. Gronenborn B. ( 1997) Engineering resistance against tomato yellow leaf curl virus (TYLCV) using antisense RNA. Plant Mol. Biol. 33, 351 357.
8. Chatterji A. Beachy R.N. Fauquet C.M. ( 2001) Expression of the oligomerization domain of the replication-associated protein (Rep) of Tomato leaf curl New Delhi virus interferes with DNA accumulation of heterologous geminiviruses. J. Biol. Chem. 276, 25 631 25 638.
9. Chellappan P. Masona M.V. Vanitharani R. Taylor N.J. Fauquet C.M. ( 2004a) Broad spectrum resistance to ssDNA viruses associated with transgene-induced gene silencing in cassava. Plant Mol. Biol. 56, 601 611.
10. Chellappan P. Vanitharani R. Fauquet C.M. ( 2004b) Short interfering RNA accumulation correlates with host recovery in DNA virus-infected hosts, and gene silencing targets specific viral sequences. J. Virol. 78, 7465 7477.
11. Dasgupta I. Malathi V.G. Mukherjee S.K. ( 2003) Genetic engineering for virus resistance. Curr. Sci. 84, 341 354.
12. Day A. Bejarano E. Buck K. Burrell M. Lichtenstein C. ( 1991) Expression of an antisense viral gene in transgenic tobacco confers resistance to the DNA virus tomato golden mosaic virus. Proc. Natl. Acad. Sci. USA, 88, 6721 6725.
13. Duffus J.E. ( 1987) Whitefly transmission in plant viruses. In: Current Topics in Vector of Squash Leaf Curl Virus (SqLCV) Research, Vol. 4 ( Harris K.F., ed.), pp. 73 91. New York : Springer Verlag.
14. FAO ( 2003) Cassava Production Statistics 2002. http://www.fao.org.
15. Fauquet C. Fargette D. ( 1990) African cassava mosaic virus: etiology, epidemiology and control. Plant Dis. 74, 404 411.
16. Fojtova M. van Houdt H. Depicker A. Kovarik A. ( 2003) Epigenetic switch from posttranscriptional to transcriptional silencing is correlated with promoter hypermethylation. Plant Phys. 133, 1240 1250.
17. Fondong V.N. Pita J.S. Rey M.E.C. de Kochko A. Beachy R.N. Fauquet C.M. ( 2000) Evidence of synergism between African cassava mosaic virus and a new double-recombinant geminivirus infecting cassava in Cameroon. J. Gen. Virol. 81, 287 297.
18. Frischmuth T. Stanley J. ( 1991) African cassava mosaic virus DI DNA interferes with the replication of both genomic components. Virology, 183, 539 544.
19. Gibson R.W. Legg J.P. Otim-Nape G.W. ( 1996) Unusually severe symptoms are a characteristic of the current epidemic of mosaic virus disease of cassava in Uganda. Ann. Appl. Biol. 128, 479 490.
20. Goldbach R. Bucher E. Prins M. ( 2003) Resistance mechanisms to plant viruses: an overview. Virus Res. 92, 207 212.
21. Hajdukiewicz P. Svab Z. Maliga P. ( 1994) The small, versatile pPZP family of Agrobacterium binary vectors for plant transformation. Plant Mol. Biol. 25, 989 994.
22. Hamilton A.J. Baulcombe D.C. ( 1999) A species of small antisense RNA in posttranscriptional gene silencing in plants. Science, 286, 950 952.
23. Hanley-Bowdoin L. Settlage S.B. Orozco B.M. Nagar S. Robertson D. ( 1999) Geminiviruses: Models for plant DNA replication, transcription, and cell cycle regulation. Crit. Rev. Plant Sci. 18, 71 106.
24. Hong Y. Stanley J. ( 1996) Virus resistance in Nicotiana benthamiana conferred by African cassava mosaic virus replication-associated protein (AC1) transgene. Mol. Plant-Microbe Interact. 9, 219 225.
25. Hull R. ( 2002) Matthews' Plant Virology, 4th edn. San Diego : Academic Press.
26. Klinkenberg F.A. Ellwood S. Stanley J. ( 1989) Fate of African cassava mosaic virus coat protein deletion mutants after agroinoculation. J. Gen. Virol. 70, 1837 1844.
27. Kong L.J. Orozco B.M. Roe J.L. Nagar S. Ou S. Feiler H.S. Durfee T. Miller A.B. Gruissem W. Robertson D. Hanley-Bowdoin L. ( 2000) A geminivirus replication protein interacts with the plant retinoblastoma protein through a novel domain to determine symptoms and tissue specificity of infection. EMBO J. 19, 3485 3491.
28. Lechtenberg B. Schubert D. Forsbach A. Gils M. Schmidt R. ( 2003) Neither inverted repeat T-DNA configurations nor arrangements of tandemly repeated transgenes are sufficient to trigger transgene silencing. Plant J. 34, 507 517.
29. Legg J.P. Thresh J.M. ( 2003) Cassava virus diseases in Africa. In: Proceedings of the First International Conference on Plant Virology in Sub-Saharan Africa, 4-8 June, 2003, Ibadan, Nigeria, pp. 517 552. Ibadan, Nigeria : IITA Publications.
30. Liu S.J. Bedford I.D. Briddon R.W. Markham P.G. ( 1997) Efficient whitefly transmission of African cassava mosaic geminivirus requires sequences from both genomic components. J. Gen. Virol. 7, 1791 1794.
31. Murashige T. Skoog F. ( 1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol. Plant. 15, 473 497.
32. Pietrzak M. Shillito R. Hohn T. Potrykus I. ( 1986) Expression in plants of two bacterial antibiotic resistance genes after transformation with a new plant expression vector. Nucleic Acids Res. 14, 5857 5868.
33. Pita J.S. Fondong V.N. Sangare A. Otim-Nape G.W. Ogwal S. Fauquet C.M. ( 2001) Recombination, pseudorecombination, and synergism of geminiviruses are determinant keys to the epidemic of severe cassava mosaic disease in Uganda. J. Gen. Virol. 82, 655 665.
34. Prins M. ( 2003) Broad virus resistance in transgenic plants. Trends Biotechnol. 21, 373 375.
35. Que Q. Jorgensen R.A. ( 1998) Homology-based control of gene expression patterns in transgenic petunia flowers. Dev. Genet. 22, 100 109.
36. Raemakers C.J.J.M. Schreuder M. Pereira I. Munyikwa T. Jacobsen E. Visser R.G.F. ( 2001) Progress made in FEC transformation of cassava. Euphytica, 120, 15 24.
37. Sambrook J. Fritsch E.F. Maniatis T. ( 1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor : Cold Spring Harbor Laboratory Press.
38. Sangare A. Deng D. Fauquet C.M. Beachy R.N. ( 1999) Resistance to African cassava mosaic virus conferred by a mutant of the putative NTP-binding domain of the Rep gene (AC1) in Nicotiana benthamiana. Mol. Breed. 5, 95 102.
39. Settlage S.B. Miller A.B. Gruissem W. Hanley-Bowdoin L. ( 2001) Dual interaction of a geminivirus replication accessory factor with a viral replication protein and a plant cell cycle regulator. Virology, 279, 570 576.
40. Soni R. Murray J.A.H. ( 1994) Isolation of intact DNA and RNA from plant tissues. Anal. Biochem. 218, 474 476.
41. Stanley J. Frischmuth T. Ellwood S. ( 1990) Defective viral DNA ameliorates symptoms of geminivirus infection in transgenic plants. Proc. Natl. Acad. Sci. USA, 87, 6291 6295.
42. Taylor N. Chavarriaga P. Raemakers K. Siritunga D. Zhang P. ( 2004) Development and application of transgenic technologies in cassava. Plant Mol. Biol. 56, 671 688.
43. Van Houdt H. Bleys A. Depicker A. ( 2003) RNA target sequences promote spreading of RNA silencing. Plant Phys. 131, 245 253.
44. Voinnet O. Pinto Y.M. Baulcombe D.C. ( 1999) Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc. Natl. Acad. Sci. USA, 96, 14 147 14 152.
45. Waterhouse P.M. Graham M.W. Wang M.B. ( 1998) Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc. Natl. Acad. Sci. USA, 95, 13 959 13 964.
46. Waterhouse P.M. Wang M. Lough T. ( 2001) Gene silencing as an adaptive defence against viruses. Nature, 411, 834 842.
47. Zhang P. Gruissem W. ( 2003) Efficient replication of cloned African cassava mosaic virus in cassava leaf disks. Virus Res. 92, 47 54.
48. Zhang P. Potrykus I. Puonti-Kaerlas J. ( 2000) Efficient production of transgenic cassava using negative and positive selection. Transgenic Res. 9, 405 415.
49. Zhou X.P. Liu Y.L. Calvert L. Munoz C. Otim-Nape G.W. Robinson D.J. Harrison B.D. ( 1997) Evidence that DNA-A of a geminivirus associated with severe cassava mosaic disease in Uganda has arisen by interspecific recombination. J. Gen. Virol. 78, 2101 2111.
50. Zilberman D. Cao X. Johansen L.K. Xie Z. Carrington J.C. Jacobsen S.E. ( 2004) Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats. Cell, 14, 1214 1220.