메뉴 건너뛰기




Volumn 8, Issue 3, 2006, Pages 527-530

Stereoselective synthesis of the western hemisphere of salinomycin

Author keywords

[No Author keywords available]

Indexed keywords

3-HYDROXYBUTANAL; ALDEHYDE; ALDOL; ANTIINFECTIVE AGENT; IONOPHORE; PYRAN DERIVATIVE; SALINOMYCIN;

EID: 32644436645     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol052900w     Document Type: Article
Times cited : (28)

References (26)
  • 4
    • 32644441552 scopus 로고    scopus 로고
    • note
    • First total synthesis of salinomycin disclosed by Y. Kishi in 1982 has been solely published as a lecture. For further comments, see ref 2b.
  • 16
  • 18
    • 0043231423 scopus 로고    scopus 로고
    • Chiral aldehyde 10 was prepared by Swern oxidation of the parental alcohol, which in turn was obtained following reported procedures. See: Vong, B. G.; Abraham, S.; Xiang, A. X.; Theodorakis, E. A. Org. Lett. 2003, 5, 1617-1620.
    • (2003) Org. Lett. , vol.5 , pp. 1617-1620
    • Vong, B.G.1    Abraham, S.2    Xiang, A.X.3    Theodorakis, E.A.4
  • 22
    • 32644450639 scopus 로고    scopus 로고
    • note
    • Spectroscopic data of 16 match those of ent-16 previously reported. See Supporting Information.
  • 24
    • 32644441925 scopus 로고    scopus 로고
    • note
    • The mechanistic details of such isomerization are unclear, but migration of the C=C bond promoted by the catalyst followed by nonstereoselective hydrogenation is presumably the cause of this undesired secondary reaction. (Diagram presented).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.