Adjuvant therapy with trastuzumab (Herceptin®) in primary breast cancer;Adjuvanter einsatz von trastuzumab (Herceptin®) beim primären mammakarzinom - Aktuelle datenlage und bewertung der stellungnahme des kompetenz centrums onkologie des MDK Nordrhein
ADULT;
AGED;
BREAST CANCER;
CANCER ADJUVANT THERAPY;
CANCER CHEMOTHERAPY;
CANCER IMMUNOTHERAPY;
CANCER SURVIVAL;
CLINICAL TRIAL;
FEMALE;
HEART FUNCTION;
HUMAN;
MAJOR CLINICAL STUDY;
REVIEW;
TREATMENT OUTCOME;
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel and epirubicin chemotherapy: Results of a randomised trial in human epidermal growth factor receptor 2-positive operable breast cancer
Buzdar AU, Ibrahim NK, Francis D et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel and epirubicin chemotherapy: results of a randomised trial in human epidermal growth factor receptor 2-positive operable breast cancer. J Clin Oncol 2005; 23: 3676-3682
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
EBCTCG. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365: 1687-1717
Meeting highlights: International expert consensus on the primary therapy of early breast cancer
Goldhirsch A, Glick JH, Gelber RD et al. Meeting highlights: international expert consensus on the primary therapy of early breast cancer. Ann Oncol 2005; 16: 1569-1583
Trastuzumab after adjuvant chemotherapy in HER2 positive breast cancer
Piccart-Gebhart M, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2 positive breast cancer. N Engl J Med 2005; 253: 1659-1672
Trastuzumab plus adjuvant chemotherapy for Operable Her-2 Positive Breast Cancer
Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for Operable Her-2 Positive Breast Cancer. N Engl J Med 2005; 353: 1673-1684
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses Her2
Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses Her2. N Engl J Med 2001; 344: 783-792
Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node positive human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP-B31
Tan-Chiu E, Yothers G, Romond E et al. Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node positive human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP-B31. J Clin Oncol 2005; 23: 7811-7819