메뉴 건너뛰기




Volumn 110, Issue 2, 2006, Pages 143-152

Neuroendocrine and metabolic effects of adipocyte-derived hormones

Author keywords

Adiponectin; Adipose tissue; Hypothalamus; Leptin; Neuropeptide; Resistin

Indexed keywords

CORTICOSTEROID; CYTOKINE; GLUCOSE; LEPTIN; LIPID; RESISTIN;

EID: 32644432147     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20050243     Document Type: Review
Times cited : (54)

References (105)
  • 1
    • 0033657074 scopus 로고    scopus 로고
    • Leptin and the neuroendocrinology of fasting
    • Ahima, R. S. (2000) Leptin and the neuroendocrinology of fasting. Front. Horm. Res. 26, 42-56
    • (2000) Front. Horm. Res. , vol.26 , pp. 42-56
    • Ahima, R.S.1
  • 3
    • 0036678477 scopus 로고    scopus 로고
    • Adipose tissue mass can be regulated through the vasculature
    • Rupnick, M. A., Panigrahy, D., Zhang, C. Y. et al. (2002) Adipose tissue mass can be regulated through the vasculature. Proc. Natl. Acad. Sci. U.S.A. 99, 10730-10735
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 10730-10735
    • Rupnick, M.A.1    Panigrahy, D.2    Zhang, C.Y.3
  • 4
    • 2942703809 scopus 로고    scopus 로고
    • Reversal of obesity by targeted ablation of adipose tissue
    • Kolonin, M. G., Saha, P. K., Chan, L., Pasqualini, R. and Arap, W. (2004) Reversal of obesity by targeted ablation of adipose tissue. Nat. Med. 10, 625-632
    • (2004) Nat. Med. , vol.10 , pp. 625-632
    • Kolonin, M.G.1    Saha, P.K.2    Chan, L.3    Pasqualini, R.4    Arap, W.5
  • 5
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn, P. and Wood, I. S. (2004) Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br. J. Nutr. 92, 347-355
    • (2004) Br. J. Nutr. , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 6
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu, H., Barnes, G. T., Yang, Q. et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112, 1821-1830
    • (2003) J. Clin. Invest. , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 8
    • 0842324779 scopus 로고    scopus 로고
    • Obesity wars: Molecular progress confronts an expanding epidemic
    • Flier, J. S. (2004) Obesity wars: molecular progress confronts an expanding epidemic. Cell 116, 337-350
    • (2004) Cell , vol.116 , pp. 337-350
    • Flier, J.S.1
  • 9
    • 84958689411 scopus 로고
    • The role of depot fat in the hypothalamic control of food intake in the rat
    • Kennedy, G. C. (1953) The role of depot fat in the hypothalamic control of food intake in the rat. Proc. R. Soc. Lond. B. Biol. Sci. 140, 578-596
    • (1953) Proc. R. Soc. Lond. B. Biol. Sci. , vol.140 , pp. 578-596
    • Kennedy, G.C.1
  • 10
    • 0000736325 scopus 로고
    • Obese, a new mutation in the house mouse
    • Ingalls, A. M., Dickie, M. M. and Snell, G. D. (1950) Obese, a new mutation in the house mouse. J. Hered. 41, 317-318
    • (1950) J. Hered. , vol.41 , pp. 317-318
    • Ingalls, A.M.1    Dickie, M.M.2    Snell, G.D.3
  • 11
    • 0014608866 scopus 로고
    • Effects of parabiosis of normal with genetically diabetic mice
    • Coleman, D. L. and Hummel, K. P. (1969) Effects of parabiosis of normal with genetically diabetic mice. Am. J. Physiol. 217, 1298-1304
    • (1969) Am. J. Physiol. , vol.217 , pp. 1298-1304
    • Coleman, D.L.1    Hummel, K.P.2
  • 13
    • 0028946288 scopus 로고
    • Erratum
    • Erratum (1995) Nature (London) 374, 479
    • (1995) Nature (London) , vol.374 , pp. 479
  • 14
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman, J. (1998) Leptin and the regulation of body weight in mammals. Nature (London) 395, 763-770
    • (1998) Nature (London) , vol.395 , pp. 763-770
    • Friedman, J.1
  • 16
    • 16944364768 scopus 로고    scopus 로고
    • Human leptin levels are pulsatile and inversely related to pituitary-adrenal function
    • Licinio, J., Mantzoros, C., Negrao, A. B. et al. (1997) Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nat. Med. 3, 575-579
    • (1997) Nat. Med. , vol.3 , pp. 575-579
    • Licinio, J.1    Mantzoros, C.2    Negrao, A.B.3
  • 17
    • 0029896530 scopus 로고    scopus 로고
    • Role of leptin in the neuroendocrine response to tasting
    • Ahima, R. S., Prabakaran, D., Mantzoros, C. et al. (1996) Role of leptin in the neuroendocrine response to tasting. Nature (London) 382, 250-252
    • (1996) Nature (London) , vol.382 , pp. 250-252
    • Ahima, R.S.1    Prabakaran, D.2    Mantzoros, C.3
  • 18
    • 15144356418 scopus 로고    scopus 로고
    • Sex differences in circulating human leptin pulse amplitude: Clinical implications
    • Licinio, J., Negrao, A. B., Mantzoros, C. et al. (1998) Sex differences in circulating human leptin pulse amplitude: clinical implications. J. Clin. Endocrinol. Metab. 83, 4140-4147
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 4140-4147
    • Licinio, J.1    Negrao, A.B.2    Mantzoros, C.3
  • 19
    • 0030942844 scopus 로고    scopus 로고
    • The leptin receptor
    • Tartaglia, L. A. (1997) The leptin receptor. J. Biol. Chem. 272, 6093-6096
    • (1997) J. Biol. Chem. , vol.272 , pp. 6093-6096
    • Tartaglia, L.A.1
  • 20
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • Bjorbaek, C., Uotani, S., da Silva, B. and Flier, J. S. (1997) Divergent signaling capacities of the long and short isoforms of the leptin receptor. J. Biol. Chem. 272, 32686-32695
    • (1997) J. Biol. Chem. , vol.272 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    Da Silva, B.3    Flier, J.S.4
  • 21
    • 0000430395 scopus 로고    scopus 로고
    • Divergent roles of SHP-2 in ERK activation by leptin receptors
    • Bjorbaek, C., Buchholz, R. M., Davis, S. M. et al. (2001) Divergent roles of SHP-2 in ERK activation by leptin receptors. J. Biol. Chem. 276, 4747-4755
    • (2001) J. Biol. Chem. , vol.276 , pp. 4747-4755
    • Bjorbaek, C.1    Buchholz, R.M.2    Davis, S.M.3
  • 22
    • 2342444310 scopus 로고    scopus 로고
    • Leptin receptor signaling and regulation of mammalian physiology
    • Myers, Jr, M. G. (2004) Leptin receptor signaling and regulation of mammalian physiology. Recent Prog. Horm. Res. 59, 287-304
    • (2004) Recent Prog. Horm. Res. , vol.59 , pp. 287-304
    • Myers Jr., M.G.1
  • 24
    • 0034776770 scopus 로고    scopus 로고
    • Selective deletion of leptin receptor in neurons leads to obesity
    • Cohen, P., Zhao, C., Cai, X. et al. (2001) Selective deletion of leptin receptor in neurons leads to obesity. J. Clin. Invest. 108, 1113-1121
    • (2001) J. Clin. Invest. , vol.108 , pp. 1113-1121
    • Cohen, P.1    Zhao, C.2    Cai, X.3
  • 25
    • 1842584949 scopus 로고    scopus 로고
    • Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
    • Gao, Q., Wolfgang, M. J., Neschen, S. et al. (2004) Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation. Proc. Natl. Acad. Sci. U.S.A. 101, 4661-4666
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 4661-4666
    • Gao, Q.1    Wolfgang, M.J.2    Neschen, S.3
  • 26
    • 0037456304 scopus 로고    scopus 로고
    • STAT3 signalling is required for leptin regulation of energy balance but not reproduction
    • Bates, S. H., Stearns, W. H., Dundon, T. A. et al. (2003) STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature (London) 421, 856-859
    • (2003) Nature (London) , vol.421 , pp. 856-859
    • Bates, S.H.1    Stearns, W.H.2    Dundon, T.A.3
  • 27
    • 2942733252 scopus 로고    scopus 로고
    • Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis
    • Balthasar, N., Coppari, R., McMinn, J. et al. (2004) Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron 42, 983-991
    • (2004) Neuron , vol.42 , pp. 983-991
    • Balthasar, N.1    Coppari, R.2    McMinn, J.3
  • 28
    • 3142782772 scopus 로고    scopus 로고
    • Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
    • Howard, J. K., Cave, B. J., Oksanen, L. J., Tzameli, I., Bjorbaek, C. and Flier, J. S. (2004) Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3, Nat. Med. 10, 734-738
    • (2004) Nat. Med. , vol.10 , pp. 734-738
    • Howard, J.K.1    Cave, B.J.2    Oksanen, L.J.3    Tzameli, I.4    Bjorbaek, C.5    Flier, J.S.6
  • 29
    • 3142723983 scopus 로고    scopus 로고
    • Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
    • Mori, H., Hanada, R., Hanada, T. et al. (2004) Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nat. Med. 10, 739-743
    • (2004) Nat. Med. , vol.10 , pp. 739-743
    • Mori, H.1    Hanada, R.2    Hanada, T.3
  • 30
    • 0033575993 scopus 로고    scopus 로고
    • Effects of recombinant leptin therapy in a child with congenital leptin deficiency
    • Farooqi, I. S., Jebb, S. A., Langmack, G. et al. (1999) Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N. Engl. J. Med. 341, 879-884
    • (1999) N. Engl. J. Med. , vol.341 , pp. 879-884
    • Farooqi, I.S.1    Jebb, S.A.2    Langmack, G.3
  • 31
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
    • Ozata, M., Ozdemir, I. C. and Licinio, J. (1999) Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J. Clin. Endocrinol. Metab. 84, 3686-3695.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 3686-3695
    • Ozata, M.1    Ozdemir, I.C.2    Licinio, J.3
  • 33
    • 0035514934 scopus 로고    scopus 로고
    • Partial leptin deficiency and human adiposity
    • Farooqi, I. S., Keogh, J. M., Kamath, S. et al. (2001) Partial leptin deficiency and human adiposity. Nature (London) 414, 34-35
    • (2001) Nature (London) , vol.414 , pp. 34-35
    • Farooqi, I.S.1    Keogh, J.M.2    Kamath, S.3
  • 34
    • 0037651108 scopus 로고    scopus 로고
    • The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men
    • Chan, J. L., Heist, K., DePaoli, A. M., Veldhuis, J. D. and Mantzoros, C. S. (2003) The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J. Clin. Invest. 111, 1409-1421
    • (2003) J. Clin. Invest. , vol.111 , pp. 1409-1421
    • Chan, J.L.1    Heist, K.2    Depaoli, A.M.3    Veldhuis, J.D.4    Mantzoros, C.S.5
  • 35
    • 4344690525 scopus 로고    scopus 로고
    • Recombinant human leptin in women with hypothalamic amenorrhea
    • Welt, C. K., Chan, J. L., Bullen, J. et al. (2004) Recombinant human leptin in women with hypothalamic amenorrhea. N. Engl. J. Med. 351, 987-997
    • (2004) N. Engl. J. Med. , vol.351 , pp. 987-997
    • Welt, C.K.1    Chan, J.L.2    Bullen, J.3
  • 36
    • 8744234075 scopus 로고    scopus 로고
    • Endocrine and metabolic effects of physiologic r-metHuLeptin administration during acute caloric deprivation in normal-weight women
    • Schurgin, S., Canavan, B., Koutkia, P., Depaoli, A. M. and Grinspoon, S. (2004) Endocrine and metabolic effects of physiologic r-metHuLeptin administration during acute caloric deprivation in normal-weight women. J. Clin. Endocrinol. Metab. 89, 5402-5409
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 5402-5409
    • Schurgin, S.1    Canavan, B.2    Koutkia, P.3    Depaoli, A.M.4    Grinspoon, S.5
  • 37
    • 12944321844 scopus 로고    scopus 로고
    • The long-term effect of recombinant methionyl human leptin therapy on hyperandrogenism and menstrual function in female and pituitary function in male and female hypoleptinemic lipodystrophic patients
    • Musso, C., Cochran, E., Javor, E., Young, J., Depaoli, A.M. and Gorden, P. (2005) The long-term effect of recombinant methionyl human leptin therapy on hyperandrogenism and menstrual function in female and pituitary function in male and female hypoleptinemic lipodystrophic patients. Metab., Clin. Exp. 54, 255-263
    • (2005) Metab., Clin. Exp. , vol.54 , pp. 255-263
    • Musso, C.1    Cochran, E.2    Javor, E.3    Young, J.4    Depaoli, A.M.5    Gorden, P.6
  • 38
    • 21344447493 scopus 로고    scopus 로고
    • Long-term efficacy of leptin replacement in patients with generalized lipodystrophy
    • Javor, E. D., Cochran, E. K., Musso, C., Young, J. R., Depaoli, A. M. and Gorden, P. (2005) Long-term efficacy of leptin replacement in patients with generalized lipodystrophy. Diabetes 4, 1994-2002
    • (2005) Diabetes , vol.4 , pp. 1994-2002
    • Javor, E.D.1    Cochran, E.K.2    Musso, C.3    Young, J.R.4    Depaoli, A.M.5    Gorden, P.6
  • 39
    • 4544286790 scopus 로고    scopus 로고
    • Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency
    • McDuffie, J. R., Riggs, P. A., Calis, K. A. et al. (2004) Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency. J. Clin. Endocrinol. Metab. 89, 4258-4263
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4258-4263
    • McDuffie, J.R.1    Riggs, P.A.2    Calis, K.A.3
  • 40
    • 4143090543 scopus 로고    scopus 로고
    • N-acetylation of hypothalamic alpha-melanocyte-stimulating hormone and regulation by leptin
    • Guo, L., Munzberg, H., Stuart, R. C., Nillni, E. A. and Bjorbaek, C. (2004) N-acetylation of hypothalamic alpha-melanocyte-stimulating hormone and regulation by leptin. Proc. Natl. Acad. Sci. U.S.A. 101, 11797-11802
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 11797-11802
    • Guo, L.1    Munzberg, H.2    Stuart, R.C.3    Nillni, E.A.4    Bjorbaek, C.5
  • 41
    • 0000659858 scopus 로고    scopus 로고
    • Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
    • Legradi, G., Emerson, C. H., Ahima, R. S., Flier, J. S. and Lechan, R. M. (1997) Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology 138, 2569-2576
    • (1997) Endocrinology , vol.138 , pp. 2569-2576
    • Legradi, G.1    Emerson, C.H.2    Ahima, R.S.3    Flier, J.S.4    Lechan, R.M.5
  • 42
    • 17744375347 scopus 로고    scopus 로고
    • Regulation of neuronal and glial proteins by leptin: Implications for brain development
    • Ahima, R. S., Bjorbaek, C., Osei, S. and Flier, J. S. (1999) Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology 140, 2755-2762
    • (1999) Endocrinology , vol.140 , pp. 2755-2762
    • Ahima, R.S.1    Bjorbaek, C.2    Osei, S.3    Flier, J.S.4
  • 43
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • Bouret, S. G., Draper, S. J. and Simerly, R. B. (2004) Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 304, 108-110
    • (2004) Science , vol.304 , pp. 108-110
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 44
    • 18844435641 scopus 로고    scopus 로고
    • Effect of leptin replacement on brain structure in genetically leptin-deficient adults
    • Matochik, J. A., London, E. D., Yildiz, B. O. et al. (2005) Effect of leptin replacement on brain structure in genetically leptin-deficient adults. J. Clin. Endocrinol. Metab. 90, 2851-2854
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 2851-2854
    • Matochik, J.A.1    London, E.D.2    Yildiz, B.O.3
  • 45
    • 1842529267 scopus 로고    scopus 로고
    • Rapid rewiring of arcuate nucleus feeding circuits by leptin
    • Pinto, S., Roseberry, A. G., Liu, H. et al. (2004) Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science 304, 110-115
    • (2004) Science , vol.304 , pp. 110-115
    • Pinto, S.1    Roseberry, A.G.2    Liu, H.3
  • 46
    • 0033303819 scopus 로고    scopus 로고
    • Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia
    • Ahima, R. S., Kelly, J., Elmquist, J. K. and Flier, J. S. (1999) Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology 140, 4923-4931
    • (1999) Endocrinology , vol.140 , pp. 4923-4931
    • Ahima, R.S.1    Kelly, J.2    Elmquist, J.K.3    Flier, J.S.4
  • 47
    • 0037663897 scopus 로고    scopus 로고
    • Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible
    • Banks, W. A. and Farrell, C. L. (2003) Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible. Am. J. Physiol. Endocrinol. Metab. 285, E10-E15
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285
    • Banks, W.A.1    Farrell, C.L.2
  • 50
    • 0030010388 scopus 로고    scopus 로고
    • Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
    • Chehab, F. F., Lim, M. E. and Lu, R. (1996) Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat. Genet. 12, 318-320
    • (1996) Nat. Genet. , vol.12 , pp. 318-320
    • Chehab, F.F.1    Lim, M.E.2    Lu, R.3
  • 51
    • 0030855190 scopus 로고    scopus 로고
    • Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress
    • Heiman, M. L., Ahima, R. S., Craft, L. S., Schoner, B., Stephens, T. W. and Flier, J. S. (1997) Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress. Endocrinology 138, 3859-3863
    • (1997) Endocrinology , vol.138 , pp. 3859-3863
    • Heiman, M.L.1    Ahima, R.S.2    Craft, L.S.3    Schoner, B.4    Stephens, T.W.5    Flier, J.S.6
  • 52
    • 0030683692 scopus 로고    scopus 로고
    • Leptin inhibits in vitro hypothalamic somatostatin secretion and somatostatin mRNA levels
    • Quintela, M., Senaris, R., Heiman, M. L., Casanueva, F. F. and Dieguez, C. (1997) Leptin inhibits in vitro hypothalamic somatostatin secretion and somatostatin mRNA levels. Endocrinology 138, 5641-5644
    • (1997) Endocrinology , vol.138 , pp. 5641-5644
    • Quintela, M.1    Senaris, R.2    Heiman, M.L.3    Casanueva, F.F.4    Dieguez, C.5
  • 53
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement, K., Vaisse, C., Lahlou, N. et al. (1998) A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature (London) 392, 398-401
    • (1998) Nature (London) , vol.392 , pp. 398-401
    • Clement, K.1    Vaisse, C.2    Lahlou, N.3
  • 54
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism
    • Berg, A. H., Combs, T. P. and Scherer, P. E. (2002) ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol. Metab. 13, 84-89
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 55
    • 14844327755 scopus 로고    scopus 로고
    • Adiponectin: A relevant player in PPARγ-agonist-mediated improvements in hepatic insulin sensitivity?
    • Bouskila, M., Pajvani, U. B. and Scherer, P. E. (2005) Adiponectin: a relevant player in PPARγ-agonist-mediated improvements in hepatic insulin sensitivity? Int. J. Obes. Relat. Metab. Disord. 29 (Suppl. 1), S17-S23
    • (2005) Int. J. Obes. Relat. Metab. Disord. , vol.29 , Issue.SUPPL. 1
    • Bouskila, M.1    Pajvani, U.B.2    Scherer, P.E.3
  • 56
    • 0036063777 scopus 로고    scopus 로고
    • Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
    • Maeda, N., Shimomura, I., Kishida, K. et al. (2002) Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat. Med. 8, 731-737
    • (2002) Nat. Med. , vol.8 , pp. 731-737
    • Maeda, N.1    Shimomura, I.2    Kishida, K.3
  • 57
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg, A. H., Combs, T. P., Du, X., Brownlee, M. and Scherer, P. E. (2001) The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7, 947-953
    • (2001) Nat. Med. , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 58
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi, T., Kamon, J., Waki, H. et al. (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7, 941-946
    • (2001) Nat. Med. , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 59
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi, T., Kamon, J., Ito, Y. et al. (2004) Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature (London) 423, 762-769
    • (2004) Nature (London) , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3
  • 60
    • 32644435786 scopus 로고    scopus 로고
    • Erratum
    • Erratum (2004) Nature (London) 431-1123
    • (2004) Nature (London) , pp. 431-1123
  • 61
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki, T. and Yamauchi, T. (2005) Adiponectin and adiponectin receptors. Endocr. Rev. 26, 439-451
    • (2005) Endocr. Rev. , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 62
    • 10744224100 scopus 로고    scopus 로고
    • Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats
    • Shklyaev, S., Aslanidi, G., Tennant, M. et al. (2003) Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats. Proc. Natl. Acad. Sci. U.S.A. 100, 14217-14222
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 14217-14222
    • Shklyaev, S.1    Aslanidi, G.2    Tennant, M.3
  • 63
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas, E., Tsao, T. S., Saha, A. K. et al. (2002) Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc. Natl. Acad. Sci. U.S.A. 99, 16309-16313
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3
  • 64
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis, J., Tsao, T. S., Javorschi, S. et al. (2001) Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc. Natl. Acad. Sci. U.S.A. 98, 2005-2010
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.S.2    Javorschi, S.3
  • 65
    • 2442659256 scopus 로고    scopus 로고
    • Adiponectin acts in the brain to decrease body weight
    • Qi, Y., Takahashi, N., Hileman, S. M. et al. (2004) Adiponectin acts in the brain to decrease body weight. Nat Med. 10, 524-529
    • (2004) Nat Med. , vol.10 , pp. 524-529
    • Qi, Y.1    Takahashi, N.2    Hileman, S.M.3
  • 66
    • 2942709582 scopus 로고    scopus 로고
    • Erratum
    • Erratum (2004) Nat. Med. 10, 649
    • (2004) Nat. Med. , vol.10 , pp. 649
  • 67
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan, C. M., Bailey, S. T., Bhat, S. et al. (2001) The hormone resistin links obesity to diabetes. Nature (London) 409, 307-312
    • (2001) Nature (London) , vol.409 , pp. 307-312
    • Steppan, C.M.1    Bailey, S.T.2    Bhat, S.3
  • 69
    • 0035487109 scopus 로고    scopus 로고
    • Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-γ action in humans
    • Savage, D. B., Sewter, C. P., Klenk, E. S. et al. (2001) Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-γ action in humans. Diabetes 50, 2199-2202
    • (2001) Diabetes , vol.50 , pp. 2199-2202
    • Savage, D.B.1    Sewter, C.P.2    Klenk, E.S.3
  • 70
    • 2442707674 scopus 로고    scopus 로고
    • Disulfide-dependent multimeric assembly of resistin family hormones
    • Patel, S. D., Rajala, M. W., Rossetti, L., Scherer, P. E. and Shapiro, L. (2004) Disulfide-dependent multimeric assembly of resistin family hormones. Science 304, 1154-1158
    • (2004) Science , vol.304 , pp. 1154-1158
    • Patel, S.D.1    Rajala, M.W.2    Rossetti, L.3    Scherer, P.E.4    Shapiro, L.5
  • 71
    • 4043085036 scopus 로고    scopus 로고
    • Adenovirus-mediated chronic 'hyper-resistinemia' leads to in vivo insulin resistance in normal rats
    • Satoh, H., Nguyen, M. T., Miles, P. D., Imamura, T., Usui, I. and Olefsky, J. M. (2004) Adenovirus-mediated chronic 'hyper-resistinemia' leads to in vivo insulin resistance in normal rats. J. Clin. Invest. 114, 224-231
    • (2004) J. Clin. Invest. , vol.114 , pp. 224-231
    • Satoh, H.1    Nguyen, M.T.2    Miles, P.D.3    Imamura, T.4    Usui, I.5    Olefsky, J.M.6
  • 72
    • 3242806013 scopus 로고    scopus 로고
    • Abnormal glucose homeostasis due to chronic hyperresistinemia
    • Rangwala, S. M., Rich, A. S., Rhoades, B. et al. (2004) Abnormal glucose homeostasis due to chronic hyperresistinemia. Diabetes 53, 1937-1941
    • (2004) Diabetes , vol.53 , pp. 1937-1941
    • Rangwala, S.M.1    Rich, A.S.2    Rhoades, B.3
  • 73
    • 10744225368 scopus 로고    scopus 로고
    • Regulation of tasted blood glucose by resistin
    • Banerjee, R. R., Rangwala, S. M., Shapiro, J. S. et al. (2004) Regulation of tasted blood glucose by resistin. Science 303, 1195-1198
    • (2004) Science , vol.303 , pp. 1195-1198
    • Banerjee, R.R.1    Rangwala, S.M.2    Shapiro, J.S.3
  • 74
    • 4043082182 scopus 로고    scopus 로고
    • Role of resistin in diet-induced hepatic insulin resistance
    • Muse, E. D., Obici, S., Bhanot, S. et al. (2004) Role of resistin in diet-induced hepatic insulin resistance. J. Clin. Invest. 114, 232-239
    • (2004) J. Clin. Invest. , vol.114 , pp. 232-239
    • Muse, E.D.1    Obici, S.2    Bhanot, S.3
  • 76
    • 0038506117 scopus 로고    scopus 로고
    • Resistin and adiponectin-of mice and men
    • Stumvoll, M. and Haring, U. (2002) Resistin and adiponectin-of mice and men. Obes. Res. 10, 1197-1199
    • (2002) Obes. Res. , vol.10 , pp. 1197-1199
    • Stumvoll, M.1    Haring, U.2
  • 77
    • 4544338791 scopus 로고    scopus 로고
    • Novel resistin promoter polymorphisms: Association with serum resistin level in Japanese obese individuals
    • Azuma, K., Oguchi, S., Matsubara, Y. et al. (2004) Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals. Horm. Metab. Res. 36, 564-570
    • (2004) Horm. Metab. Res. , vol.36 , pp. 564-570
    • Azuma, K.1    Oguchi, S.2    Matsubara, Y.3
  • 78
    • 15744403957 scopus 로고    scopus 로고
    • Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Quebec Family Study
    • Bouchard, L., Weisnagel, S. J., Engert, J. C. et al. (2004) Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Quebec Family Study. J. Endocrinol. Invest. 27, 1003-1009
    • (2004) J. Endocrinol. Invest. , vol.27 , pp. 1003-1009
    • Bouchard, L.1    Weisnagel, S.J.2    Engert, J.C.3
  • 79
    • 9144244927 scopus 로고    scopus 로고
    • Resistin and type 2 diabetes: Regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes
    • McTernan, P. G., Fisher, F. M., Valsamakis, G. et al. (2003) Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes. J. Clin. Endocrinol. Metab. 88, 6098-6106
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 6098-6106
    • McTernan, P.G.1    Fisher, F.M.2    Valsamakis, G.3
  • 80
    • 22044437691 scopus 로고    scopus 로고
    • Associations between serum resistin levels and insulin resistance, inflammation, and coronary artery disease
    • Ohmori, R., Momiyama, Y., Kato, R. et al. (2005) Associations between serum resistin levels and insulin resistance, inflammation, and coronary artery disease. J. Am. Coll. Cardiol. 46, 379-380
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 379-380
    • Ohmori, R.1    Momiyama, Y.2    Kato, R.3
  • 81
    • 25144447626 scopus 로고    scopus 로고
    • Role of resistin in obesity, insulin resistance and Type II diabetes
    • 76a Kusminski, C. M., McTernan, P. G. and Kumar, S. (2005) Role of resistin in obesity, insulin resistance and Type II diabetes. Clin. Sci. 109, 243-256
    • (2005) Clin. Sci. , vol.109 , pp. 243-256
    • Kusminski, C.M.1    McTernan, P.G.2    Kumar, S.3
  • 82
    • 23044439100 scopus 로고    scopus 로고
    • Human resistin stimulates the pro-inflammatory cytokines TNF-α and IL-12 in macrophages by NF-κB-dependent pathway
    • Silswal, N., Singh, A. K., Aruna, B., Mukhopadhyay, S., Ghosh, S. and Ehtesham, N. Z. (2005) Human resistin stimulates the pro-inflammatory cytokines TNF-α and IL-12 in macrophages by NF-κB-dependent pathway. Biochem. Biophys. Res. Commun. 334, 1092-1101
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 1092-1101
    • Silswal, N.1    Singh, A.K.2    Aruna, B.3    Mukhopadhyay, S.4    Ghosh, S.5    Ehtesham, N.Z.6
  • 85
    • 3042784523 scopus 로고    scopus 로고
    • Regulation of resistin expression and circulating levels in obesity, diabetes, and tasting
    • Rajala, M. W., Qi, Y., Patel, H. R. et al. (2004) Regulation of resistin expression and circulating levels in obesity, diabetes, and tasting. Diabetes 53, 1671-1679
    • (2004) Diabetes , vol.53 , pp. 1671-1679
    • Rajala, M.W.1    Qi, Y.2    Patel, H.R.3
  • 86
    • 0035815608 scopus 로고    scopus 로고
    • A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation
    • Kim, K. H., Lee, K., Moon, Y. S. and Sul, H. S. (2001) A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation. J. Biol. Chem. 276, 11252-11256
    • (2001) J. Biol. Chem. , vol.276 , pp. 11252-11256
    • Kim, K.H.1    Lee, K.2    Moon, Y.S.3    Sul, H.S.4
  • 87
    • 2342643579 scopus 로고    scopus 로고
    • Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity
    • Kim, K. H., Zhao, L., Moon, Y., Kang, C. and Sul, H. S. (2004) Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 101, 6780-6785
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 6780-6785
    • Kim, K.H.1    Zhao, L.2    Moon, Y.3    Kang, C.4    Sul, H.S.5
  • 88
    • 0036875211 scopus 로고    scopus 로고
    • Adipose tissue intracrinology: Potential importance of local androgen/estrogen metabolism in the regulation of adiposity
    • Belanger, C., Luu-The, V., Dupont, P. and Techernof, A. (2002) Adipose tissue intracrinology: potential importance of local androgen/estrogen metabolism in the regulation of adiposity. Horm. Metab. Res. 34, 737-745
    • (2002) Horm. Metab. Res. , vol.34 , pp. 737-745
    • Belanger, C.1    Luu-The, V.2    Dupont, P.3    Techernof, A.4
  • 89
    • 0036875203 scopus 로고    scopus 로고
    • Sex steroid biosynthesis in white adipose tissue
    • Meseguer, A., Puche, C. and Cabero, A. (2002) Sex steroid biosynthesis in white adipose tissue. Horm. Metab. Res. 34, 731-736
    • (2002) Horm. Metab. Res. , vol.34 , pp. 731-736
    • Meseguer, A.1    Puche, C.2    Cabero, A.3
  • 90
    • 0035716557 scopus 로고    scopus 로고
    • Aromatase-deficient (ArKO) mice accumulate excess adipose tissue
    • Jones, M. E., Thorburn, A. W., Britt, K. L. et al. (2001) Aromatase-deficient (ArKO) mice accumulate excess adipose tissue. J. Steroid Biochem. Mol. Biol. 79, 3-9
    • (2001) J. Steroid Biochem. Mol. Biol. , vol.79 , pp. 3-9
    • Jones, M.E.1    Thorburn, A.W.2    Britt, K.L.3
  • 91
    • 12944276957 scopus 로고    scopus 로고
    • Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity
    • Jones, M. E., Thorburn, A. W., Britt, K. L. et al. (2000) Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc. Natl. Acad. Sci. U.S.A. 97, 12735-12740
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 12735-12740
    • Jones, M.E.1    Thorburn, A.W.2    Britt, K.L.3
  • 92
    • 0037291609 scopus 로고    scopus 로고
    • Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency
    • Takeda, K., Toda, K., Saibara, T. et al. (2003) Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency. J. Endocrinol. 176, 237-246
    • (2003) J. Endocrinol. , vol.176 , pp. 237-246
    • Takeda, K.1    Toda, K.2    Saibara, T.3
  • 93
    • 18844461988 scopus 로고    scopus 로고
    • Estrogen - The good, the bad, and the unexpected
    • Simpson, E. R., Misso, M., Hewitt, K. N. et al. (2005) Estrogen-the good, the bad, and the unexpected. Endocr. Rev. 26, 322-330
    • (2005) Endocr. Rev. , vol.26 , pp. 322-330
    • Simpson, E.R.1    Misso, M.2    Hewitt, K.N.3
  • 94
    • 13944255183 scopus 로고    scopus 로고
    • 11β-hydroxysteroid dehydrogenases: Changing glucocorticoid action
    • Seckl, J. R. (2004) 11β-Hydroxysteroid dehydrogenases: changing glucocorticoid action. Curr. Opin. Pharmacol. 4, 597-602
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 597-602
    • Seckl, J.R.1
  • 95
    • 0035824440 scopus 로고    scopus 로고
    • A transgenic model of visceral obesity and the metabolic syndrome
    • Masuzaki, H., Paterson, J., Shinyama, H. et al. (2001) A transgenic model of visceral obesity and the metabolic syndrome. Science 294, 2166-2170
    • (2001) Science , vol.294 , pp. 2166-2170
    • Masuzaki, H.1    Paterson, J.2    Shinyama, H.3
  • 96
    • 85047693986 scopus 로고    scopus 로고
    • Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice
    • Masuzaki, H., Yamamoto, H., Kenyon, C. J. et al. (2003) Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. J. Clin. Invest. 112, 83-90
    • (2003) J. Clin. Invest. , vol.112 , pp. 83-90
    • Masuzaki, H.1    Yamamoto, H.2    Kenyon, C.J.3
  • 97
    • 0035798621 scopus 로고    scopus 로고
    • Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice
    • Morton, N. M., Holmes, M. C., Fievet, C. et al. (2001) Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice. J. Biol. Chem. 276, 41293-41300
    • (2001) J. Biol. Chem. , vol.276 , pp. 41293-41300
    • Morton, N.M.1    Holmes, M.C.2    Fievet, C.3
  • 98
    • 12144291638 scopus 로고    scopus 로고
    • Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11β-hydroxysteroid dehydrogenase type 1-deficient mice
    • Morton, N. M., Paterson, J. M., Masuzaki, H. et al. (2004) Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11β-hydroxysteroid dehydrogenase type 1-deficient mice. Diabetes 53, 931-938
    • (2004) Diabetes , vol.53 , pp. 931-938
    • Morton, N.M.1    Paterson, J.M.2    Masuzaki, H.3
  • 99
    • 18744413888 scopus 로고    scopus 로고
    • Association studies between microsatellite markers within the gene encoding human 11β-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism
    • Draper, N., Echwald, S. M., Lavery, G. G. et al. (2002) Association studies between microsatellite markers within the gene encoding human 11β-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism. J. Clin. Endocrinol. Metab. 87, 4984-4990
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4984-4990
    • Draper, N.1    Echwald, S.M.2    Lavery, G.G.3
  • 100
    • 23844516967 scopus 로고    scopus 로고
    • 11β-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action
    • Draper, N. and Stewart, P. M. (2005) 11β-Hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action. J. Endocrinol. 186, 251-271
    • (2005) J. Endocrinol. , vol.186 , pp. 251-271
    • Draper, N.1    Stewart, P.M.2
  • 101
    • 19944433652 scopus 로고    scopus 로고
    • Vistatin: A protein secreted by visceral fat that mimics the effects of insulin
    • Fukuhara, A., Matsuda, M., Nishizawa, M. et al. (2005) Vistatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 307, 426-430
    • (2005) Science , vol.307 , pp. 426-430
    • Fukuhara, A.1    Matsuda, M.2    Nishizawa, M.3
  • 102
    • 12344327355 scopus 로고    scopus 로고
    • Vistatin: A new adipokine
    • Hug, C. and Lodish, H. K (2005) Vistatin: a new adipokine. Science 307, 366-367
    • (2005) Science , vol.307 , pp. 366-367
    • Hug, C.1    Lodish, H.K.2
  • 103
    • 23044473651 scopus 로고    scopus 로고
    • Visceral adipose tissue derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity
    • Hida, K., Wada, J., Eguchi, J. Y. S. et al. (2005) Visceral adipose tissue derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity. Proc. Natl. Acad. Sci. U.S.A. 102, 10610-10615
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 10610-10615
    • Hida, K.1    Wada, J.2    Eguchi, J.Y.S.3
  • 104
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang, Q., Graham, T. E., Mody, N. et al. (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature (London) 436, 356-362
    • (2005) Nature (London) , vol.436 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3
  • 105
    • 0033025413 scopus 로고    scopus 로고
    • Evidence for an essential role of megalin in transepithelial transport of retinol
    • Christensen, E. I., Moskaug, J. O., Vorum, H. et al. (1999) Evidence for an essential role of megalin in transepithelial transport of retinol. J. Am. Soc. Nephrol. 10, 685-695
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 685-695
    • Christensen, E.I.1    Moskaug, J.O.2    Vorum, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.