Dose-dependent transthyretin inhibition of T4 uptake from cerebrospinal fluid in sheep

Neuroscience Letters

Volumn 396, Issue 1, 2006, Pages 7-11

  Chen, R L ^a   Kassem, N A ^a   Preston, J E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Ageing; Cerebrospinal fluid; Choroid plexus; Efflux; Thyroxine uptake; Transthyretin

Indexed keywords

BOVINE SERUM ALBUMIN; IODINE 125; PREALBUMIN; THYROXINE;

ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CEREBELLUM; CEREBROSPINAL FLUID; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; FRONTAL CORTEX; HORMONE BINDING; HORMONE TRANSPORT; INCUBATION TIME; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; SHEEP; STATISTICAL SIGNIFICANCE;

AGE FACTORS; AGING; ANIMALS; BINDING, COMPETITIVE; BLOOD-BRAIN BARRIER; BRAIN; CEREBROSPINAL FLUID; CHOROID PLEXUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IODINE RADIOISOTOPES; LATERAL VENTRICLES; MALE; PREALBUMIN; SHEEP; THYROXINE;

EID: 32544435648     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.11.003     Document Type: Article

References (30)

1. T. Abe, T. Suzuki, M. Unno, T. Tokui, and I. Sadayoshi Thyroid hormone transporters: recent advances Trends Endocrinol. Metab. 13 2002 215 220
2. L. Bartalena Recent achievements in studies on thyroid hormone-binding proteins Endocrinol. Rev. 11 1990 47 64
3. L.Z. Bito, M.W. Bradbury, and H. Davson Factors affecting the distribution of iodide and bromide in the center nervous system J. Physiol. 185 1966 323 354
4. J.P. Chanoine, S. Alex, S.L. Fang, S. Stone, J.L. Leonard, J. Köhrle, and L.E. Braverman Role of transthyretin in the transport of thyroxine from the blood to the choroid plexus, the cerebrospinal fluid, and the brain Endocrinology 130 1992 933 938
5. R.L. Chen, S. Athauda, N. Kassem, Y. Zhang, M.B. Segal, and J.E. Preston Decreased transthyretin synthesis at old sheep blood-cerebrospinal barrier J. Gerontol. A. 60 7 2005 852 858
6. H. Davson K. Welch M.B. Segal Physiology and Pathophysiology of the Cerebrospinal Fluid 1996 Churchill Livingston London
7. M.B. Dratman, F.L. Crutchfield, and M.B. Schoenhoff Transport of iodothyronines from bloodstream to brain: contributions by blood:brain and choroid plexus:cerebrospinal fluid barriers Brain Res. 554 1991 229 236
8. S.R. Ennis, A. Novotny, J. Xiang, P. Shakui, T. Masada, W. Stummer, D.E. Smith, and R.F. Keep Transport of 5-aminolevulinic acid between blood and brain Brain Res. 959 2 2003 226 234
9. K.M. Hargreaves, and W.M. Pardridge Neutral amino acid transport at the human blood-brain barrier J. Biol. Chem. 263 36 1988 19392 19397
10. M. Hashimoto, S. Hossain, and S. Masumura Effect of aging on plasma membrane fluidity of rat aortic endothelial cells Exp. Gerontol. 34 1999 687 698
11. J. Herbert, J.N. Wilcox, K.T. Pham, R.T. Fremeau Jr., M. Zevian, A. Dwork, D.R. Soprano, A. Makover, D.S. Goodman, and E.A. Zimmerman Transthyretin: a choroid plexus-specific transport protein in human brain Neurology 36 1986 900 911
12. A.P. Hillier The rate of triiodothyronine dissociation from binding sites in human plasma Acta Endocrinol. (Copenh.) 80 1 1975 49 57
13. A.J. Hulbert Thyroid hormones and their effects: a new perspective Biol. Rev. 75 2000 519 631
14. N.A. Kassem, The transport and distribution of thyroxine (T4) from the cerebrospinal fluid into brain, Ph.D. thesis, University of London, 2004.
15. S. Kuchler-Bopp, M.E. Ittel, J.B. Dietrich, A. Reeber, M. Zaepfel, and J.P. Delaunoy The presence of transthyretin in rat ependymal cells is due to endocytosis and not synthesis Brain Res. 793 1998 219 230
16. Y. Long, L. Zou, H. Liu, H. Lu, X. Yuan, C.S. Robertson, and K. Yang Altered expression of randomly selected genes in mouse hippocampus after traumatic brain injury J. Neurosci. Res. 71 2003 710 720
17. C.M. Mendel, R.A. Weisiger, A.L. Jones, and R.R. Cavalieri Thyroid hormone-binding proteins in plasma facilitate uniform distribution of thyroxine within tissues: a perfused rat liver study Endocrinology 120 1987 1742 1749
18. H.A. Montecinos, H. Richter, T. Caprile, and E.M. Rodriguez Synthesis of thansthyretin by the ependymal cells of the subcommissural organ Cell Tissue Res. 320 5 2005 487 499
19. J.H. Oppenheimer, M.I. Surks, and H.L. Schwartz The metabolic significance of exchangeable cellular thyroxine Recent Prog. Horm. Res. 25 1969 381 422
20. J.A. Palha, R. Fernandes, G.M. de Escobar, V. Episkopou, M. Gottesman, and M.J. Saraiva Transthyretin regulates thyroid hormone levels in the choroid plexus, but not in the brain parenchyma: study in a transthyretin-null mouse model Endocrinology 141 9 2000 3267 3272
21. W.M. Pardridge Carrier-mediated transport of thyroid hormones through the rat blood-brain barrier: primary role of albumin-bound hormone Endocrinology 105 3 1979 605 612
22. S.P. Porterfield, and C.E. Hendrich The role of thyroid hormones in prenatal and neonatal neurological development - current perspectives Endocrinol. Rev. 14 1 1993 94 106
23. H. Reiber Dynamics of brain derived proteins in CSF Clinica Chimica Acta 310 2001 173 186
24. G. Schreiber, S.J. Richardson, and P. Prapunpoj Structure and expression of the transthyretin gene in the choroid plexus: a model for the study of the mechanism of evolution Microsc. Res. Tech. 52 1 2001 21 30
25. B.R. Southwell, W. Duan, D. Alcorn, C. Brack, S.J. Richardson, J. Köhrle, and G. Schreiber Thyroxine transport to the brain: role of protein synthesis by the choroid plexus Endocrinology 133 5 1993 2116 2126
26. R. Spector Riboflavin transport in the central nervous system: characterization and effects of drugs J. Clin. Invest. 66 1980 821 831
27. N. Strazielle, and J.E. Preston Transport across the choroid plexuses in vivo and in vitro S. Nag The Blood-Brain Barrier 2003 Humana Press Totowa, New Jersey 291 304
28. H. Takagi Orthodox sometimes generates paradox Intern. Med. 44 2005 163 164
29. T. Tenenbaum, R. Adam, I. Eggelnpohler, D. Matalon, A. Seibt, G.E. Novotny, H.J. Galle, and H. Schroten Strain-dependent disruption of blood-cerebrospinal fluid barrier by Streptococcus suis in vitro FEMS Immunol. Med. Microbiol. 44 1 2005 25 34
30. P.M. Yen Physiological and molecular basis of thyroid hormone action Physiol. Rev. 81 2001 1097 1142