NMR and molecular modeling studies of the interaction between wheat germ agglutinin and the β-D-GlcpNAc-(1→6)-α-D-Manp epitope present in glycoproteins of tumor cells

Biochemistry

Volumn 43, Issue 30, 2004, Pages 9647-9654

  Lycknert, Kristina ^a   Edblad, Malin ^a   Imberty, Anne ^b   Widmalm, Göran ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b CENTRE DE RECHERCHES SUR LES MACROMOLÉCULES VÉGÉTALES CERMAV CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; COMPUTER SIMULATION; PROTEINS; PROTONS; SATURATION (MATERIALS COMPOSITION); SUGARS; TORSIONAL STRESS;

DISACCHARIDES; MOLECULAR MODELING;

NUCLEAR MAGNETIC RESONANCE;

ACETIC ACID DERIVATIVE; BETA DEXTRO N ACETYL DEXTRO GLUCOSAMINE(1-6) ALPHA DEXTRO MANNOSE DISSACHARIDE; DISACCHARIDE; EPITOPE; GLYCOCONJUGATE; GLYCOPROTEIN; HYDROXYMETHYL GROUP; LECTIN; METHYL GROUP; OLIGOSACCHARIDE; TUMOR MARKER; UNCLASSIFIED DRUG; WHEAT GERM AGGLUTININ;

ARTICLE; BINDING SITE; CELL SURFACE; CONFORMATION; CRYSTAL STRUCTURE; HYDROGEN BOND; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; TUMOR CELL;

BINDING SITES; DISACCHARIDES; EPITOPES; GLYCOPROTEINS; HUMANS; METHYLMANNOSIDES; MODELS, CHEMICAL; MODELS, MOLECULAR; NEOPLASM PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTONS; SOLUTIONS; THERMODYNAMICS; WHEAT GERM AGGLUTININS;

TRITICUM AESTIVUM;

EID: 3242888034     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0499011     Document Type: Article

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