Genital ambiguity with a Y chromosome: Does gender assignment matter?

Journal of Pediatric Endocrinology and Metabolism

Volumn 17, Issue 6, 2004, Pages 825-839

  Houk, Christopher P ^a   Dayner, Jennifer ^a   Lee, Peter A ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Genital ambiguity; Intersex; Male pseudohermaphroditism; Mixed gonadal dysgenesis

Indexed keywords

ANTIDEPRESSANT AGENT; CHORIONIC GONADOTROPIN; DESMOPRESSIN; GONADORELIN DERIVATIVE; GROWTH HORMONE; TESTOSTERONE;

ADOLESCENT; ADULT; AMBIGUITY; ANAMNESIS; CASE REPORT; CENTRAL NERVOUS SYSTEM; CHILD PARENT RELATION; CHILD REARING; DEPRESSION; GENDER IDENTITY; HUMAN; KARYOTYPE; MALE; MALE PSEUDOHERMAPHRODITISM; MASCULINITY; NOCTURNAL ENURESIS; QUALITY OF LIFE; REVIEW; SCHOOL CHILD; SEX ROLE; SHORT STATURE; SOCIAL PSYCHOLOGY; TEMPERAMENT; UROLOGIC SURGERY; Y CHROMOSOME;

EID: 3242883828     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2004.17.6.825     Document Type: Review

References (13)

1. Migeon CJ, Wisniewski AB, Gearhart JP, Meyer-Bahlburg HF, Rock JA, Brown TR, Casella SJ, Maret A, Ngai KM, Money J, Berkovitz GD. Ambiguous genitalia with perineoscrotal hypospadias in 46,XY individuals: long-term medical, surgical, and psychosexual outcome. Pediatrics 2002; 110: e31.
2. Migeon CJ, Wisniewski AB, Brown TR, Rock JA, Meyer-Bahlburg HF, Money J, Berkovitz GD. 46,XY intersex individuals: phenotypic and etiologic classification, knowledge of condition, and satisfaction with knowledge in adulthood. Pediatrics 2002; 110: e32.
3. Money J, Hampson J, Hampson J. Hermaphroditism: recommendations concerning assignment of sex, change of sex, and psychologic management. Bull Johns Hopkins Hosp 1955; 97: 284-300.
4. Dreger AD. Hermaphrodites and the Medical Invention of Sex. Cambridge, MA: Harvard University Press, 1998.
5. Dreger AD, ed. Intersex in the Age of Ethics. Hagerstown, MD: University Publishing Group, 1999.
6. Money J, Ehrhardt AA. Man and Woman Boy and Girl. Baltimore, MD: Johns Hopkins University Press, 1972.
7. Hrabovszky Z, Hutson JM. Androgen imprinting of the brain in animal models and humans with intersex disorders: review and recommendations. J Urol 2002; 168: 2142-2148.
8. Lee PA. A perspective on the approach to the intersex child born with genital ambiguity. J Pediatr Endocrinol Metab 2004; 17: 133-140.
9. Alizai NK, Thomas DF, Lilford RJ, Batchelor AG, Johnson N. Feminizing genitoplasty for congenital adrenal hyperplasia: What happens at puberty? J Urol 1999; 161: 1588-1591.
10. Minto CL, Liao LM, Woodhouse CR, Ransley PG, Creighton SM. The effect of clitoral surgery on sexual outcome in individuals who have intersex conditions with ambiguous genitalia: a cross-sectional study. Lancet 2003; 361: 1252-1257.
11. Reiner W, Gearhart JP. Discordant sexual identity in some genetic males with cloacal extrophy assigned to female sex at birth. N Engl J Med 2004; 350: 333-341.
12. Bin-Abbas B, Conte FA, Grumbach MM, Kaplan SL. Congenital hypogonadotropic hypogonadism and micropenis: effect of testosterone treatment on adult penile size. Why sex reversal is not indicated. J Pediatr 1999; 134: 579-583.
13. Cohen-Kettenis PT, Owen A, Kaijser VG, Bradley SJ, Zucker KJ. Demographic characteristics, social competence and behavior problems in children with gender identity disorder: a cross-national, cross-clinic comparative analysis. J Abnorm Child Psychol 2003; 31: 41-53.