Synthesis and biological activity of 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3, 4-b]-1,3,4-thiadiazoles

Molecules

Volumn 7, Issue 8, 2002, Pages 681-689

  Zhang, Li Xue ^a   Zhang, An Jiang ^a   Chen, Xian Xing ^a   Lei, Xin Xiang ^a   Nan, Xiang Yun ^a   Chen, Dong Yong ^a   Zhang, Zi Yi ^b  

^a WENZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

Biological activity; Furan ring; Spectral characterization; Synthesis; Triazolothiadiazoles

Indexed keywords

3 (2 FURANYL) 6 (1 NAPHTHYLMETHYL) 1,2,4 TRIAZOLE[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2 AMINOPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2 CHLOROPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2 HYDROXYPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2 METHOXYPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2 NITROPHENYLMETHYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2 QUINOLYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (2,4 DICHLOROPHENOXYMETHYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (3 CHLOROPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (3 PYRIDYL) 1,2,4 TRIAZOLE[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (3,5 DINITROPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (4 AMINOPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (4 METHOXYPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 (4 NITROPHENYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 BENZYL 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 PHENYL 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURANYL) 6 PHENYLOXYMETHYL 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; 3 (2 FURYL) 4 AMINO 5 MERCAPTO 1,2,4 TRIAZOLE; 3,6 BIS(2 FURANYL) 1,2,4 TRIAZOLO[3,4 B] 1,3,4 THIADIAZOLE; THIADIAZOLE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MUNG BEAN; PROTON NUCLEAR MAGNETIC RESONANCE; STATISTICAL SIGNIFICANCE;

EID: 3242883827     PISSN: 14203049     EISSN: None     Source Type: Journal    
DOI: 10.3390/70800681     Document Type: Article

References (5)

1. Zhang Z.Y.; Chen X. Synthesis and Antibacterial Activity of 3-(4-Pyridyl)-6-aryl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles. Acta Chim. Sinica, 1991, 49, 513-520
2. Zhang Z.Y.; Li M.; Zhao L.; Li Z.M.; Liao R.A. Synthesis of 3-Alkyl/Aryl-6-(3-pyridyl)-s-triazolo[3,4-b]-1,3,4-thiadiazoles. Chin. J. Org. Chem., 1993, 13, 397-402
3. Gupta R.; Sudan S.; Mengi V.; Kachroo P. L. Indian J. Chem., Sect. B, 1996, 35, 621-623
4. Zhang L.X.; Zhang Z.Y.; Zeng F.L. Studies on Synthesis and Spectral Properties of 1-Nicotinyl-4-arylaminosemicarbazides and Substituted-1,2,4- triazoles. Chem. J. Chin. Univ., 1990, 11, 148-153
5. Reid J. R.; Heindel N. D. J. Heterocyclic Chem., 1976, 13, 925-928