Crystal and molecular structure of 2,6-dimethyl-3-acetyl-5-carbomethoxy-4- (4′-methoxyphenyl)-1,4-dihydropyridine

Journal of Chemical Crystallography

Volumn 34, Issue 7, 2004, Pages 441-445

  Mahendra, M ^a   Doreswamy, B H ^a   Sridhar, M A ^a   Prasad, J Shashidhara ^b   Patel, Gautam R ^b   Patel, Jignesh A ^b   Shah, Anamik ^b  

^a UNIVERSITY OF MYSORE   (India)

^b SAURASHTRA UNIVERSITY   (India)

Author keywords

1,4 Dihydropyridine derivatives; crystal structure

Indexed keywords

2,6 DIMETHYL 3 ACETYL 5 CARBOMETHOXY 4 (4' METHOXYPHENYL) 1,4 DIHYDROPYRIDINE; DIHYDROPYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; PARAMETER; X RAY DIFFRACTION;

EID: 3242876173     PISSN: 10741542     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOCC.0000035384.34214.b8     Document Type: Article

References (26)

1. Loev, B.; Goodman, M.M.; Snader, K.M.; Tedeschi, R.; Macko, E. J. Med. Chem. 1995, 17, 956.
2. Bossert, F.; Horstmann, H.; Meyer, H.; Vater, W. Arzneim.-Forsch./Drug Res. 1979, 29(I), 226.
3. Iwanami, M.; Shibanuma, T.; Fujimoto, M.; Kawai, R.; Tamazawa, K.; Takenaka, T.; K. Takahashi, Murakami, M. Chem. Pharm. Bull. 1979, 27, 1426.
4. Imai, H.; Matsui, K.; Ochi, S.; Nakazawa, M.; Nakagawa, Y.; Imai, S. Arzneim.-Forsch./Drug Res. 1987, 37(II), 12.
5. Derk, K.; Stoepel, K.; Leibowitz, D.; Taylor, R.; Vanov, S. In Nitrendipine; Scriabine, A.; Vanov, S.; Deck, K., Eds.; Urban and Schwarzenberg: Baltimore, 1984; 397 p.
6. Triggle, D.J. In Cardiovascular Pharmacology: Antonaccio, M., Ed.; Raven Press: NewYork 1990; pp. 107-160.
7. Wehingner, E.; Gross, R. Ann. Rep. Med. Chem. 1986, 21, 85.
8. Janis, R.A.; Triggle, D. J. J. Med. Chem. 1983, 26, 775.
9. Coburn, R.A.; Wierzba, M.; Suto, M.J.; Solo, A.J.; Triggle, A.M., Triggle, D. J. J. Med. Chem. 1988, 31, 2103.
10. Mahmoudian, M.; Richards, W. C. J. Chem. Soc. Chem. Commun. 1986, 739.
11. Triggle, D.J.; Langs, D.A.; Janis, R.A. Med. Res. Rev. 1989, 9, 123.
12. Fossheim, R. J. Med. Chem, 1986, 29, 305.
13. Fossheim, R. Acta Chem. Scand. 1986, B41, 581.
14. Shah, A.; Gaveriya, H.; Motohashi, N.; Kawase, M.; Saito, S.; Sakagami, H.; Satoh, K.; Solymosi, A.; Walfard, K.; Molnar, J. Anticancer Res. 2000, 20, 373.
15. Gunics, G.; Motohashi, N.; Molnar, J.; Farkas, S.; Kawase, M.; Saito, S.; Shah, A. Anticancer Res. 2001, 21, 269.
16. Gunics, G.; Farkas, S.; Motohashi, N.; Shah, A.; Harsukh, G.; Kawase, M.; Molnar, J. Int. J. Antimicrobial Agents 2002, 20, 227.
17. Kawase, M.; Shah, A.; Gaveriya, H.; Motohashi, N.; Sakagami, H.; Varga, A.; Molnar, J. Biol. Med. Chem. 2002, 10, 1051.
18. Lokanath, N.K.; Sridhar, M.A.; Prasad, J.S.; Joshi, M.; Thaker, D.A.; Shah, A. Z. Kris. - New Cryst. Struct. 1997, 212, 13.
19. Devarajegowda, H.C.; Prasad, J.S.; Sridhar, M.A.; Gaveriya, H.C.; Shah, A. Mol. Cryst. Liq. Cryst. 2000, 348, 301.
20. Otwinowski, Z.; Minor, W. In Methods in Enzymology, Vol. 276: Macromolecular Crystallography, Part A; Carter, C.W., Jr.; Sweet, R.M.; Eds.; Academic Press: University of Texas, Southwestern Medical Center, Dallas, 1997; pp. 307-326.
21. Sheldrick, G.M. SHELXS-97; University of Göttingen: Germany, 1997.
22. Sheldrick, G.M. SHELXL-97; University of Göttingen: Germany, 1997.
23. Johnson, C. K. ORTEP-II, A Fortran Thermal-Ellipsoid Plot Program, Report ORNL-5138; Oak Ridge National Laboratory: Oak Ridge, Tennessee, 1976.
24. Fossheim, R.; Joslyn, A.; Solo, A. J.; Luchowski, E.; Rutledge, A.; Triggle, D. J. J. Med. Chem. 1988, 31, 300.
25. Miyamae, A.; Koda, S.; Morimoto, Y. Chem. Pharm. Bull. 1986, 34, 3071.
26. Fossheim, R.; Svarteng, K.; Mostad, A.; Romming, C.; Shelter, E.; Triggle, D. J. J. Med. Chem. 1982, 25, 126.