Synthesis and biological characterization of novel hybrid 7-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro- naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 16, 2004, Pages 4361-4373

  Dutta, Aloke K ^a   Venkataraman, Sylesh K ^a   Fei, Xiang Shu ^a   Kolhatkar, Rohit ^a   Zhang, Shijun ^a   Reith, Maarten E A ^b  

^a WAYNE STATE UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 [2 [[4 (2,3 DICHLOROPHENYL)PIPERAZIN 1 YL]ETHYL]PROPYLAMINO] 5,6,7,8 TETRAHYDRONAPHTHALEN 2 OL; 7 [[4 (4 PHENYLPIPERAZIN 1 YL)BUTYL]PROP 2 YNYLAMINO] 5,6,7,8 TETRAHYDRONAPHTHALEN 2 OL; APOMORPHINE; BENZENE DERIVATIVE; DOPAMINE 3 RECEPTOR; N6 [2 (4 PHENYLPIPERAZIN 1 YL)ETHYL] N6 PROPYL 4,5,6,7 TETRAHYDROBENZOTHIAZOLE 2,6 DIAMINE; NAPHTHYL GROUP; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 7 ((2 (4 PHENYL PIPERAZIN 1 YL) ETHYL) PROPYL AMINO) 5,6,7,8 TETRAHYDRO NAPHTHALEN 2 OL; 7-((2-(4-PHENYL-PIPERAZIN-1-YL)-ETHYL)-PROPYL-AMINO)-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-OL; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; DRD3 PROTEIN, HUMAN; DRD3 PROTEIN, RAT; NAPHTHALENE DERIVATIVE; PIPERAZINE DERIVATIVE; TETRALIN DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG BINDING; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENANTIOMER; IN SITU HYBRIDIZATION; ISOMER; MITOGENESIS; NONHUMAN; RACEMIC MIXTURE; RAT; STEREOCHEMISTRY; ANIMAL; CELL LINE; CHEMISTRY; DRUG POTENTIATION; HUMAN; SYNTHESIS;

ANIMALS; CELL LINE; DOPAMINE AGONISTS; HUMANS; NAPHTHALENES; PIPERAZINES; RATS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; TETRAHYDRONAPHTHALENES;

EID: 3242815390     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.06.019     Document Type: Article

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