Feasibility of a novel design of high resolution parallax-free compton enhanced PET scanner dedicated to brain research

Physics in Medicine and Biology

Volumn 49, Issue 12, 2004, Pages 2547-2562

  Braem, A ^a   Llatas, M Chamizo ^b   Chesi, E ^a   Correia, J G ^c   Garibaldi, F ^d   Joram, C ^a   Mathot, S ^a   Nappi, E ^e   Ribeiro da Silva, M ^f   Schoenahl, F ^g   Seguinot J ^a   Weilhammer, P ^a   Zaidi, H ^g  

^a CERN   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e INFN SEZIONE DI BARI   (Italy)

^f CENTRO DE FÍSICA NUCLEAR DA UNIVERSIDADE DE LISBOA   (Portugal)

^g GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CAMERAS; CRYSTALS; IMAGE RECONSTRUCTION; NEUROLOGY; PHOTONS; POSITRON EMISSION TOMOGRAPHY; SCINTILLATION COUNTERS;

COMPTON SCATTERING; HYBRID PHOTON DETECTORS (HPD);

BIOMEDICAL ENGINEERING;

ALUMINUM DERIVATIVE; BROMIDE; CESIUM; LANTHANUM; YTTRIUM;

ARTICLE; BRAIN SCINTISCANNING; COMPTON EFFECT; COST BENEFIT ANALYSIS; CRYSTAL; ELECTRONICS; ERROR; FEASIBILITY STUDY; GEOMETRY; MAMMOGRAPHY; MONTE CARLO METHOD; PHOTON; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; PROCESS DESIGN; RADIATION DETECTION; SCINTILLATION CAMERA; THREE DIMENSIONAL IMAGING;

BRAIN; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEASIBILITY STUDIES; GAMMA CAMERAS; IMAGE ENHANCEMENT; IMAGING, THREE-DIMENSIONAL; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; RESEARCH; SENSITIVITY AND SPECIFICITY;

EID: 3242807530     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/49/12/006     Document Type: Article

References (24)

1. Agostinelli S et al 2003 GEANT4 - a simulation toolkit Nucl. Instrum. Methods A 506 250-303
2. Bouwens L et al 2001 Resolution recovery for list-mode reconstruction in SPECT Phys. Med. Biol. 46 2239-53
3. Braem A et al 2004 Novel design of a parallax free Compton enhanced PET scanner Nucl. Instrum. Methods A at press
4. Braem A et al 2003a The Pad HPD: a highly segmented hybrid photodiode Nucl. Instrum. Methods A 497 202-5
5. Braem A et al 2003b Novel design of high-resolution parallax-free Compton enhanced PET scanner dedicated to brain research Conf. Proc. 1st Int. Meeting on Applied Physics (Badajoz, Spain, 15-18 Oct. 2003) pp 86-67
6. Chesi E et al 2003 The VATAGP3 test set-up and first results from measurements with the VATAGP3 chip Nucl. Instrum. Methods A (submitted)
7. Green P J 1990 Bayesian reconstructions from emission tomography data using a modified EM algorithm IEEE Trans. Med. Imaging 9 84-93
8. Joram C 1999 Large area hybrid photodiodes Nucl. Phys. B 78 407-15
9. Karp J S et al 2003 Performance of a brain PET camera based on anger-logic gadolinium oxyorthosilicate detectors J. Nucl. Med. 44 1340-9
10. Moses W W 2002 Current trends in scintillator detectors and materials Nucl. Instrum. Methods A 487 123-8
11. Nelson W R, Hirayama H and Rogers D W O 1985 The EGS4 code system SLAC-256 (Stanford Linear Accelerator Center, Stanford, CA)
12. Phelps M E 2000 PET: the merging of biology and imaging into molecular imaging J. Nucl. Med. 41 661-81
13. Phelps M E and Cherry S R 1998 The changing design of positron imaging systems Clin. Pos. Imaging 1 31-45
14. Qi J and Leahy R M 2000 Resolution and noise properties of MAP reconstruction for fully 3-D PET IEEE Trans. Med. Imaging 19 493-506
15. Schmand M et al 1998 Performance results of a new DOI detector block for a high resolution PET-LSO research tomograph HRRT IEEE Trans. Nucl. Sci. 45 3000-6
16. Séguinot J et al 2004 Design and performance of a 3D axial PET scanner (submitted)
17. Surti S et al 2003 Investigation of lanthanum scintillators for 3-D PET IEEE Trans. Nucl. Sci. 50 348-54
18. Watanabe M et al 2002 A new high-resolution PET scanner dedicated to brain research IEEE Trans. Nucl. Sci. 49 634-9
19. Weilhammer P 2000 Silicon-based HPD development: sensors and front ends Nucl. Instrum. Methods A 446 289-98
20. Wienhard K et al 2002 The ECAT HRRT: performance and first clinical application of the new high resolution research tomograph IEEE Trans. Nucl. Sci. 49 104-10
21. Zaidi H, Herrmann Scheurer A and Morel C 1999 An object-oriented Monte Carlo simulator for 3D positron tomographs Comput. Meth. Prog. Biomed. 58 133-45
22. Zaidi H, Montandon M-L and Slosman D O 2003 Magnetic resonance imaging-guided attenuation and scatter corrections in three-dimensional brain positron emission tomography Med. Phys. 30 937-48
23. Zaidi H, Montandon M-L and Slosman D O 2004 Attenuation compensation in cerebral 3D PET: effect of the attenuation map on absolute and relative quantitation Eur. J. Nucl. Med. Mol. Imaging 31 52-63
24. Zaidi H and Sossi V 2004 Correction for image degrading factors is essential for accurate quantification of brain function using PET Med. Phys. 31 423-6