Challenging diagnosis - Icterus associated with a single perforating duodenal ulcer after long-term nonsteroidal antiinflammatory drug administration in a dog

Canadian Veterinary Journal

Volumn 45, Issue 6, 2004, Pages 507-510

  Duerr, Felix M ^a   Carr, Anthony P ^a   Bebchuk, Trevor N ^a   Pople, Neil C ^b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b Prairie Diagnostic Services   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; AMPICILLIN; CEFALEXIN; CEFAZOLIN; CORTICOSTEROID DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; DIAZEPAM; ENROFLOXACIN; FAMOTIDINE; FRESH FROZEN PLASMA; HEPARIN; MELOXICAM; METOCLOPRAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OXYMORPHONE; RINGER LACTATE SOLUTION;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL LAMENESS; ARTICLE; CHOLECYSTOSTOMY; DISEASE ASSOCIATION; DOG DISEASE; DRUG DOSE REGIMEN; DUODENUM PERFORATION; DUODENUM ULCER; ECHOGRAPHY; GASTRODUODENOSTOMY; HYPERBILIRUBINEMIA; LAPAROTOMY; LONG TERM CARE; MALE; NONHUMAN; OBSTRUCTIVE JAUNDICE; TIBIA OSTEOTOMY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DIAGNOSIS, DIFFERENTIAL; DOG DISEASES; DOGS; DUODENAL ULCER; JAUNDICE; LIVER; MALE; PEPTIC ULCER HEMORRHAGE; PEPTIC ULCER PERFORATION; THIAZINES; THIAZOLES;

ANIMALIA; CANIS FAMILIARIS; ICTERUS;

EID: 3242793452     PISSN: 00085286     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Hall JA. Diseases of the stomach. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine. 5th ed. vol 2. Philadelphia: WB Saunders, 2000:1154-1182.
2. Hinton LE, McLoughlin MA, Johnson SE, Weisbrode SE. Spontaneous gastroduodenal perforation in 16 dogs and seven cats (1982-1999). J Am Anim Hosp Assoc 2002;38:176-187.
3. Forsyth SF, Guilford WG, Lawoko CRO. Endoscopic evaluation of the gastroduodenal mucosa following non-steroidal anti-inflammatory drug administration in the dog. N Z Vet J 1996;44: 179-181.
4. Forsyth SF, Guilford WG, Haslett SJ, et al. Endoscopy of the gastroduodenal mucosa after carprofen, meloxicam and ketoprofen administration in dogs. J Small Anim Pract 1998;39:421-424.
5. Reed S. Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler. Can Vet J 2002;43:971-972.
6. Stanton ME, Bright RM. Gastroduodenal ulceration in dogs - Retrospective study of 43 cases and literature review. J Vet Intern Med 1989;3:238-244.
7. Center SA. Chronic hepatitis, cirrhosis, breed-specific hepatopathies, copper storage hepatopathy, suppurative hepatitis, granulomatous hepatitis, and idiopathic hepatic fibrosis. In: Guilford WG, Center SA, Strombeck DR, Williams DA, Meyer DJ, eds. Strombeck's Small Animal Gastroenterology. 3rd ed. Philadelphia: WB Saunders, 1996:748-749.
8. Trauner M, Fickert P, Stauber RE. Review: Inflammation induced cholestasis. J Gastroenterol Hepatol 1999;14:946-959.
9. Taboada J, Meyer DJ. Cholestasis associated with extrahepatic bacterial infection in five dogs. J Vet Intern Med 1989;3: 216-221.
10. Steenbergen WV, Ponette E, Marchal G, Fevery J, DeGroote JD. Distal common bile duct stenosis secondary to benign duodenal ulceration: Report of a case. Gastrointest Radiol 1990;15: 215-217.
11. Guelfi JF, Braun JP, Benard P, Rico AG. Value of so called cholestasis markers in the dog: An experimental study. Res Vet Sci 1982;33:309-312.
12. Kay-Mugford P, Benn SJ, LaMarre J, Conlon P. In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs. Am J Vet Res 2000;61:802-810.
13. Jones CJ, Streppa HK, Harmon BG, Budsberg SC. In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. Am J Vet Res 2002;63: 1527-1531.