Appropriate methods to assess the effectiveness and efficacy of treatments or interventions to control cancer pain

Journal of Palliative Medicine

Volumn 7, Issue 3, 2004, Pages 423-430

  Bausewein, Claudia ^a   Higginson, Irene J ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; PLACEBO;

ARTICLE; CANCER PAIN; CANCER PATIENT; CASE CONTROL STUDY; CLINICAL PRACTICE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFICACY; HUMAN; METHODOLOGY; OUTCOMES RESEARCH; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; RELIABILITY; VALIDATION PROCESS;

CROSS-OVER STUDIES; EPIDEMIOLOGIC METHODS; HUMANS; NEOPLASMS; OUTCOME ASSESSMENT (HEALTH CARE); PAIN; PALLIATIVE CARE; RANDOMIZED CONTROLLED TRIALS; TREATMENT OUTCOME;

EID: 3242785561     PISSN: 10966218     EISSN: None     Source Type: Journal    
DOI: 10.1089/1096621041349572     Document Type: Article

References (29)

1. Stricker G: The Relationship Between Efficacy and Effectiveness. Prevention & Treatment, 2003;3:Article 10.〈www.journals.apa.org/ prevention/volume3/pre0030010c.html〉 (Last accessed March 20, 2004).
2. McQuay HJ, Moore RA: Pain measurement, study design and validity. In: McQuay HJ, Moore RA (eds): An Evidenced-Based Resource for Pain Relief. Oxford: Oxford University Press, 1998, pp. 14-18.
3. Pocock SJ: Clinical Trials: A Practical Approach. Chichester: A Wiley Medical Publication, 1983.
4. McQuay HJ, Moore A: Need for rigorous assessment in palliative care. BMJ 1994;309:1315-1316.
5. Ahmedzai S, Brooks D: Transdermal Fentanyl versus sustained-release oral morphine in cancer pain: Preference, efficacy and quality of life. J Pain Symptom Manage 1997;13:254-261.
6. Harden RN, Bruehl S: Conducting clinical trials to establish drug efficacy in chronic pain. Am J Phys Med Rehabil 2002;80:547-557.
7. Kirkham SR, Abel J: Placebo-controlled trials in palliative care: The argument against. Palliat Med 1997;11:489-492.
8. Hardy JR: Placebo-controlled trials in palliative care: The argument for. Palliat Med 1997;11:415-418.
9. Max MA, Portenoy RK: Pain research: Designing clinical trials in palliative care. In: Doyle D, Hanks G, MacDonald N (eds): Oxford Textbook of Palliative Medicine. 2nd ed. Oxford: Oxford University Press, 1999, pp. 167-178.
10. Rinck GC, van den Bos GA, Kleijnen J, de Haes HJ, Schade E, Veenhof CH: Methodologic Issues in Effectiveness Research on Palliative Cancer Care: A Systematic Review. J Clin Oncol 1997;15:1697-1707.
11. Rutten EH, Crul BJ, van der Toorn PP, Otten AW, Dirksen R: Pain characteristics help to predict the analgesic efficacy of radiotherapy for the treatment of cancer pain. Pain 1997;69:131-135.
12. Guyatt GH, Sackett DL, Cook DJ: User's guide to the medical literature. II How to use an article about therapy or prevention. A. Are the results of the study valid? JAMA 1993;270:2598-2601.
13. Rees E: The ethics and practicalities in palliative care research: An overview. Int J Palliat Nurs 2001;7:489-492.
14. Abu-Saad HH: Evaluation of palliative care. In: Abu-Saad H (ed): Evidence-Based Palliative Care. Oxford: Blackwell Science, 2001. Pages 37-41.
15. DeCock KM. HIV drug strategies in the West-and AIDS everywhere else. An interview with Kevin M. DeCock. Interview by Mark Mascolini. J Int Assoc Physicians AIDS Care 1997;3(2):23-6, 28-31.
16. Rothman KJ: Types of epidemiologic study. In: Rothman KJ (ed): Epidemiology: An Introduction. Oxford: Oxford University Press, 2002. Pages 57-93.
17. Schug SA, Zech D, Grond S, Jung H, Meuser T, Stobbe B: A Long-Term Survey of Morphine in Cancer Pain Patients. J Pain Symptom Manage 1992;7:259-266.
18. Coggon D, Rose G, Barker DJP: Epidemiology for the Uninitiated, 4th ed. London: BMJ Publishing Group, 1997.
19. Morton V, Torgerson DJ: Effects of regression to the mean on decision making in health care. BMJ 2003;326:1083-1084.
20. Bland JM, Airman DG: Statistics notes: Some examples of regression towards the mean. BMJ 1994;309:780.
21. Bowling A: Research Methods in Health Care. Buckingham: Open University Press, 2000.
22. Tugwell P, Bennett K, Feeny D, Guyatt G, Haynes RB: A framework for the evaluation of technology: the technology assessment iterative loop. In: Feeny D, Guyatt G, Tugwell P (eds): Health Care Technology: Effectiveness, Efficiency, and Public Policy. Montreal: The Institute for Research on Public Policy, 1986, pp. 41-56.
23. Guscott R, Taylor L: Lithium prophylaxis in recurrent affective illness-efficacy, effectiveness and efficiency. Br J Psychol 1994;164:741-746.
24. Hanks G, Conno F, Cherny N, Hanna M, Kalso E, Mc Quay HJ, et al. Morphine and alternative opioids in cancer pain: The EAPC recommendations. Br J Cancer 2001;84:587-593.
25. Turk DC, Rudy TE, Sorkin BA: Neglected topics in pain treatment outcome studies: Determination of success. Pain 1993;53:3-16.
26. Caraceni A, Cherny N, Feinsinger R, Kaasa S, Poulain P, Radbruch L, De Conno F: Pain Measurement Tools and Methods in Clinical Research in Palliative Care: Recommendations of an Expert Working Group of the European Association of Palliative Care. J Pain Symptom Manage 2002;23:239-255.
27. Melzack R: The McGill pain questionnaire: Major properties and scoring methods. Pain 1975;1:277-299.
28. Cleeland CS: Measurement of pain by subjective report. In: Chapman CR, Loeser JD (eds): Advances in Pain Research and Management, Vol. 12. Issues in Pain Management. New York: Raven Press, 1989, pp. 391-403.
29. Farrar JT, Young PF, LaMoreaux L, Werth JL, Poole MR: Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain 2001;94:149-158.