Minor pyrano-isoflavones from Eriosema kraussianum: Activity-, structure-, and chemical reaction studies

Phytochemistry

Volumn 65, Issue 13, 2004, Pages 1955-1961

  Drewes, Siegfried E ^a   Horn, Marion M ^a   Khan, Fatima ^a   Munro, Orde Q ^a   Dhlamini, Jabu T B ^b   Rakuambo, Christopher ^c   Marion Meyer, J J ^c  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b 10 Baverstock Street ^*  (South Africa)

^c UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Cyclization; Eriosema kraussianum; Pyrano isoflavones; Smooth muscle contraction; X ray

Indexed keywords

3,5 DIHYDROXY 7 (7 HYDROXY 2,2 DIMETHYL 2H CHROMEN 6 YL) 2,2 DIMETHYL 3,4 DIHYDRO 2H,6H PYRANO[3,2 G]CHROMEN 6 ONE; ERIOSEMA KRAUSSIANUM EXTRACT; ISOFLAVONE DERIVATIVE; KRAUSSIANONE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CORPUS CAVERNOSUM; ERIOSEMA KRAUSSIANUM; NONHUMAN; RABBIT; SMOOTH MUSCLE CONTRACTION; X RAY ANALYSIS;

CRYSTALLOGRAPHY, X-RAY; ISOFLAVONES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PLANTS, MEDICINAL;

ERIOSEMA;

EID: 3242774414     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2004.04.030     Document Type: Article

References (9)

1. Drewes S.E., Horn M.M., Khan F., Munro O.Q., Dhlamini J.T.B., Rakuambo C., Meyer J.J.M. Pyrano-isoflavones with erectile-dysfunction activity from Eriosema kraussianum. Phytochemistry. 59:2002;739-747
2. Drewes S.E., George J., Khan F. Recent findings on natural products with erectile-dysfunction activity. Phytochemistry. 62:2003;1019-1025
3. Falshaw C.P., Ollis W.D., Moore J.A., Magnus K. The constitutions of lisetin, piscidone and piscerythrone. Tetrahedron. (7):1966;333-348
4. Smalberger T.M., Vleggaar R., Weber J.C. The constitution and absolute configuration of lupinifolin and lupinifolinol, two flavanones from Tephrosia lupinifolia. Tetrahedron. 30:1974;3927-3931
5. Smalberger T.M., Vleggaar R., Weber J.C. The structure of elongatin, an isoflavone from Tephrosia elongata. Tetrahedron. 31:1975;2297-2301
6. Stevens J.F., Taylor A.W., Nickerson G.B., Ivancic M., Henning J., Haunold A., Deinzer M.L. Prenylflavonoid variation in Humulus lupulus: distribution and taxonomic significance of xanthogalenol and 4. ′-O-methylxanthohumol Phytochemistry. 53:2000;759-775
7. 13C NMR studies of some complex natural oxygen heterocycles. Tetrahedron. 37:1981;957-962
8. Watt, J.M., Breyer-Brandwijk, M.G., 1962. Medicinal and Poisonous Plants of Southern and Eastern Africa. E. and S. Livingstone, Edinburgh
9. Yankep E., Njamen D., Fotsing M.T., Fomum Z.T., Mbanya J.-C., Giner R.M., Recio C., Manez S., Rios J.L. Griffoneanone D., an isoflavone with anti-inflammatory activity from the root bark of Millettia griffoniana. Journal of Natural Products. 66:2003;1288-1290