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Volumn 34, Issue 6, 2004, Pages 591-606

Metabolism of the antineoplastic and immunosuppressive drug 2-CdA (Leustatin ®) in animals and humans

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CLADRIBINE; CLADRIBINE GLUCURONIDE; CLADRIBINE SULFATE; DRUG METABOLITE; GLUCURONIDE; IMMUNOSUPPRESSIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 3242769163     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250410001713140     Document Type: Article
Times cited : (4)

References (19)
  • 1
    • 0026799508 scopus 로고
    • Cladribine (2-chlorodeoxyadenosine)
    • BENTLER, E., 1992, Cladribine (2-chlorodeoxyadenosine). Lancet, 340, 952-956.
    • (1992) Lancet , vol.340 , pp. 952-956
    • Bentler, E.1
  • 3
    • 0025866670 scopus 로고
    • 2-Chloro-2Ç-deoxyadenosine (2-CdA): A potent chemotherapeutic and immunosuppressive nucleoside
    • BENTLER, E., PIRO, L. D. and SAVAN, A., 1991, 2-Chloro-2Ç- deoxyadenosine (2-CdA): a potent chemotherapeutic and immunosuppressive nucleoside. Leukemia and Lymphoma, 5, 1-8.
    • (1991) Leukemia and Lymphoma , vol.5 , pp. 1-8
    • Bentler, E.1    Piro, L.D.2    Savan, A.3
  • 4
    • 0017639365 scopus 로고
    • Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency, possible role of nucleoside kinase (s)
    • CARSON, D. A., KAYE, J. and SEEGMILLER, J. E., 1977, Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency, possible role of nucleoside kinase (s). Proceedings of the National Academy of Sciences, USA, 74, 5677-5681.
    • (1977) Proceedings of the National Academy of Sciences, USA , vol.74 , pp. 5677-5681
    • Carson, D.A.1    Kaye, J.2    Seegmiller, J.E.3
  • 7
    • 0020612685 scopus 로고
    • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytee
    • CARSON, D. A., WASSON, D. B., TEATLE, R. and YU, A., 1983, Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytee. Blood, 62, 737-743.
    • (1983) Blood , vol.62 , pp. 737-743
    • Carson, D.A.1    Wasson, D.B.2    Teatle, R.3    Yu, A.4
  • 9
    • 0025322413 scopus 로고
    • Tissue distribution and metabolic disposition of zidovudine in rats
    • DE MIRANDA, P., BURNETT, T. and GOOD, S. S., 1990, Tissue distribution and metabolic disposition of zidovudine in rats. Drug Metabolism and Disposition, 18, 315-320.
    • (1990) Drug Metabolism and Disposition , vol.18 , pp. 315-320
    • De Miranda, P.1    Burnett, T.2    Good, S.S.3
  • 10
    • 0025935563 scopus 로고
    • On the pharmacokinetics of 2-chloro-2′-deoxyadenosine in humans
    • LILIEMARK, J. and JULIUSSON, G., 1991, On the pharmacokinetics of 2-chloro-2′-deoxyadenosine in humans. Cancer Research, 51, 5570-5572.
    • (1991) Cancer Research , vol.51 , pp. 5570-5572
    • Liliemark, J.1    Juliusson, G.2
  • 11
    • 0027056958 scopus 로고
    • On the bioavailability of oral and subcutaneous 2-chloro-2′- deoxyadenosine in humans: Alternative routes of administration
    • LILIEMARK, J., ALBERTIONI, F., HASSAN, M. and JULIUSSON, G., 1992, On the bioavailability of oral and subcutaneous 2-chloro-2′-deoxyadenosine in humans: alternative routes of administration. Journal of Clinical Oncology, 10, 1514-1518.
    • (1992) Journal of Clinical Oncology , vol.10 , pp. 1514-1518
    • Liliemark, J.1    Albertioni, F.2    Hassan, M.3    Juliusson, G.4
  • 12
    • 0032080845 scopus 로고    scopus 로고
    • Determination of 2-chlorodeoxyadenosine (cladribine, 2-CdA) in human plasma by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry
    • MOYER, M. D., JOHANNSEN, T. and STUBBS, R. J., 1998. Determination of 2-chlorodeoxyadenosine (cladribine, 2-CdA) in human plasma by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. Journal of Pharmacological and Biomedical Analysis, 17, 45-51.
    • (1998) Journal of Pharmacological and Biomedical Analysis , vol.17 , pp. 45-51
    • Moyer, M.D.1    Johannsen, T.2    Stubbs, R.J.3
  • 13
    • 0034646216 scopus 로고    scopus 로고
    • Cladribine and progressive MS clinical and MRI outcomes of a multicenter controlled trial
    • RICE, G. P., FILIPPI, M. and COMI, G., 2000. Cladribine and progressive MS clinical and MRI outcomes of a multicenter controlled trial. Neurology, 54, 1145-1155.
    • (2000) Neurology , vol.54 , pp. 1145-1155
    • Rice, G.P.1    Filippi, M.2    Comi, G.3
  • 14
    • 0024424591 scopus 로고
    • Purine metabolism is a target for leukemia chemotherapy
    • RISCOE, M. K., BROUNS, M. C. and FITCHEN, J. H., 1989. Purine metabolism is a target for leukemia chemotherapy. Blood Reviews, 3, 162-173.
    • (1989) Blood Reviews , vol.3 , pp. 162-173
    • Riscoe, M.K.1    Brouns, M.C.2    Fitchen, J.H.3
  • 16
    • 0026573542 scopus 로고
    • Treatment of hairy cell leukemia
    • SAVEN, A. and PIRO, L. D., 1992, Treatment of hairy cell leukemia, Blood, 79, 1111-1120.
    • (1992) Blood , vol.79 , pp. 1111-1120
    • Saven, A.1    Piro, L.D.2
  • 17
    • 0022003367 scopus 로고
    • Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes
    • SETO, S., CARRERA, C. J., KUBOTA, M., WASSON, D. B. and CARSON, D. A., 1985, Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. Journal of Clinical Investigation, 75, 377-378.
    • (1985) Journal of Clinical Investigation , vol.75 , pp. 377-378
    • Seto, S.1    Carrera, C.J.2    Kubota, M.3    Wasson, D.B.4    Carson, D.A.5
  • 19
    • 3242795629 scopus 로고    scopus 로고
    • The in vivo metabolism of cladribine in the mouse, monkey and human
    • abst.comma; 7th European ISSX Meeting
    • WU, W. N., MCKOWN, L. A. MOYER, M. D. and CHEUNG, W., 1999, The in vivo metabolism of cladribine in the mouse, monkey and human. ISSX Proceedings, 14, 91 (abst.comma; 7th European ISSX Meeting).
    • (1999) ISSX Proceedings , vol.14 , pp. 91
    • Wu, W.N.1    Mckown, L.A.2    Moyer, M.D.3    Cheung, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.