A new method for detection of mercury-bound protein with a combination of gel electrophoresis and one dimensional synchrotron radiation X-ray fluorescence analysis

Journal of Occupational Health

Volumn 38, Issue 3, 1996, Pages 118-119

  Homma Takeda, Shino ^a,b   Shinyashiki, Masaru ^b   Kumagai, Yoshito ^a   Shimojo, Nobuhiro ^a  

^a Institute of Community Medicine

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Electrophoresis; Isoelectric point; Mercury; Metallothionein; Synchrotron radiation X ray fluorescence analysis

Indexed keywords

EID: 3242768554     PISSN: 13419145     EISSN: None     Source Type: Journal    
DOI: 10.1539/joh.38.118     Document Type: Article

References (8)

1. Berlin M. Mercury. In: Friberg L, Nordberg GF, and Vouk V, eds. Handbook on the toxicology of metals. Amsterdam: Elsevier Science Publishers BV, 1986: 387-445.
2. Preston GM, Jung JS, Guggino WB, Agre P. The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel. J Biol Chem 1993; 268: 17-20.
3. Shimojo N, Homma S, Nakai I, Iida A. Non-destructive synchrotron radiation X-ray fluorescence imaging of trace elements on methylmercury and selenium administered guinea pigs. Anal Lett 1991; 24: 1767-1777.
4. Homma S, Shimojo N. Nondestructive synchrotron radiation X-ray fluorescence imaging of trace elements in the kidney of rats administered organic mercury. Biomed Res Trace Elements 1991; 2: 51-56.
5. Naganuma A, Satoh M, Imura N. Prevention of lethal and renal toxicity of cis-diamminedichloroplatinum (II) by induction of metallothionein synthesis without compromising its antitumor activity in mice. Cancer Res 1987; 47: 983-987.
6. Sluyterman LAAE, Wijdenes J. Chromatofocusing: Isoelectric focusing on ion-exchange columns. II. Experimental verification. J Chromatogr 1978; 150: 31-44.
7. Nordberg M. Metallothionein and related molecules. Methods in Enzymology 1991; 205: 247-252.
8. Jacobs MB, Yamaguchi S, Goldwater LJ, Gilbert H. Determination of mercury in blood. Am Ind Hyg Assoc J 1960; 21: 475-480.