High infectious burden, low cancer incidence, and early malignancy in developing countries: A molecular hypothesis in term of the role of nitric oxide

Medical Hypotheses

Volumn 63, Issue 2, 2004, Pages 208-210

  Vijh, Ashok K ^a  

^a HYDRO QUÉBEC   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE;

CANCER; CANCER CELL; CANCER INCIDENCE; CITRIC ACID CYCLE; DEVELOPING COUNTRY; DNA SYNTHESIS; GENE MUTATION; HUMAN; IMMUNE SYSTEM; INFECTION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; STIMULUS; TUMOR CELL; TUMOR SUPPRESSOR GENE;

EID: 3242763066     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.02.023     Document Type: Article

References (4)

1. Vijh AK. Observations on the proposed relationship between infection burden and early malignancy in developing countries (e.g., India). Med Hypotheses, 2004 [in press]
2. Vijh AK. Inverse trend between estimated worldwide frequency of major cancers and inferred infectious burdens of populations: possible role of adaptive immune system. Med Hypotheses, 2004 [in press]
3. Sastry P.S.R.K., Parikh P. The earlier age of onset of malignancy in developing world is related to overall infection burden and could be due to the effect on telomere length. Med. Hypotheses. 60(4):2003;573-574
4. Snyder SH, Bredt DS. Biological roles of nitric oxide. Scientific American, May 1992; p. 68-77