Sarcomatoid variant of salivary duct carcinoma: Clinicopathologic and immunohistochemical study of eight cases with review of the literature

American Journal of Clinical Pathology

Volumn 122, Issue 2, 2004, Pages 222-231

  Nagao, Toshitaka ^a,e   Gaffey, Thomas A ^a   Serizawa, Hiromi ^b   Iwaya, Keiichi ^b   Watanabe, Akinori ^b   Yoshida, Tomoyuki ^b   Yamazaki, Kazuto ^c   Sageshima, Masato ^d   Lewis, Jean E ^a  

^a MAYO CLINIC   (United States)

^b TOKYO MEDICAL UNIVERSITY HOSPITAL   (Japan)

^c TEIKYO UNIVERSITY CHIBA MEDICAL CENTER   (Japan)

^d Akita City Hosp   (Japan)

^e Division of Anatomic Pathology   (United States)

Author keywords

Carcinosarcoma; p53; Parotid gland; Salivary duct carcinoma; Salivary gland; Sarcomatoid carcinoma

Indexed keywords

CYTOKERATIN; EPITHELIAL MEMBRANE ANTIGEN; PROTEIN P53;

ADENOMA; ADULT; AGED; CANCER GRADING; CANCER MORTALITY; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; FOLLOW UP; GENE EXPRESSION; HISTOGENESIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PAROTID GLAND TUMOR; PATHOLOGY; PRIORITY JOURNAL; REVIEW; SALIVARY GLAND CARCINOMA; SARCOMA; SURVIVAL RATE; TUMOR CLASSIFICATION; TUMOR DIFFERENTIATION; TUMOR SUPPRESSOR GENE;

EID: 3242750467     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/5J4008QRY1HWW5W4     Document Type: Review

References (44)

1. Brandwein MS, Jagirdar J, Patil J, et al. Salivary duct carcinoma (cribriform salivary carcinoma of excretory ducts): a clinicopathologic and immunohistochemical study of 12 cases. Cancer. 1990;65:2307-2314.
2. Barnes L, Rao U, Krause J,;et al. Salivary duct carcinoma, npart I: a clinicopathologic evaluation and DNA image analysis of 13 cases with review of the literature. Oral Surg Oral Med Oral Pathol. 1994;78:64-73.
3. Lewis JE, McKinney BC, Weiland LH, et al. Salivary duct carcinoma: clinicopathologic and immunohistochemical review of 26 cases. Cancer. 1996;77:223-230.
4. Kleinsasser O, Klein HJ, Hübner G. Salivary duct carcinoma: a group of salivary gland tumors analogous to mammary duct carcinoma [in German]. Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1968;192:100-105.
5. Seifert G, Sobin LH. Histological Typing of Salivary Gland Tumours. 2nd ed. Berlin, Germany: Springer-Verlag; 1991. World Health Organization International Histological Classification of Tumours.
6. Lewis JE, Olsen KD, Sebo TJ. Carcinoma ex pleomorphic adenoma: pathologic analysis of 73 cases. Hum Pathol. 2001;32:596-604.
7. Delgado R, Klimstra D, Albores-Saavedra J. Low grade salivary duct carcinoma: a distinctive variant with a low grade histology and a predominant intraductal growth pattern. Cancer. 1996;78:958-967.
8. Simpson RH, Prasad AR, Lewis JE, et al. Mucin-rich variant of salivary duct carcinoma: a clinicopathologic and immunohistochemical study of four cases. Am J Surg Pathol. 2003;27:1070-1079.
9. Henley JD, Seo IS, Dayan D, et al. Sarcomatoid salivary duct carcinoma of the parotid gland. Hum Pathol. 2000;31:208-213.
10. Ide F, Mishima K, Saito I. Sarcomatoid salivary duct carcinoma of the oral cavity. Virchows Arch. 2003;443:686-689.
11. Talmi YP, Halpren M, Finkelstein Y, et al. True malignant mixed tumour of the parotid gland. J Laryngol Otol. 1990;104:360-361.
12. Bleiweiss IJ, Huvos AG, Lara J, et al. Carcinosarcoma of the submandibular salivary gland: immunohistochemical findings. Cancer. 1992;69:2031-2035.
13. Grenko RT, Tytor M, Boeryd B. Giant-cell tumour of the salivary gland with associated carcinosarcoma. Histopathology. 1993;23:594-595.
14. Carson HJ, Tojo DP, Chow.JM, et al. Carcinosarcoma of salivary glands with unusual stromal components: report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;79:738-746.
15. Alvarez-Canas C, Rodilla IG. True malignant mixed tumor (carcinosarcoma) of the parotid gland: report of a case with immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;81:454-458.
16. Sironi M, Isimbaldi G, Claren R, et al. Carcinosarcoma of the parotid gland: cytological, clinicopathological and immunohistochemical study of a case. Pathol Res Pract. 2000;196:511-517.
17. Pang PC, To EW, Tsang WM, et al. Carcinosarcoma (malignant mixed tumor) of the parotid gland: a case report. J Oral Maxillofac Surg. 2001;59:583-587.
18. Stephen J, Batsakis JG, Luna MA, et al. True malignant mixed tumors (carcinosarcoma) of salivary glands. Oral Surg Oral Med Oral Pathol. 1986;61:597-602.
19. Gnepp DR. Malignant mixed tumors of the salivary glands: a review. Pathol Annu. 1993;28:279-328.
20. Ellis GL, Auclair PL. Tumors of the Salivary Glands. Washington, DC: Armed Forces Institute of Pathology; 1996. Atlas of Tumor Pathology; Third series, Fascicle 17.
21. Hellquist H, Michaels L. Malignant mixed tumour: a salivary gland tumour showing both carcinomatous and sarcomatous features. Virchows Arch A Pathol Anat Histopathol. 1986;409:93-103.
22. Garner SL, Robinson RA, Maves MD, et al. Salivary gland carcinosarcoma: true malignant mixed tumor. Ann Otol Rhinol Laryngol. 1989;98:611-614.
23. Gandour-Edwards RF, Donald PJ, Vogt PJ, et al. Carcinosarcoma (malignant mixed tumor) of the parotid: report of a case with a pure rhabdomyosarcoma component. Head Neck. 1994;16:379-382.
24. Gogas J, Markopoulos C, Karydakis V, et al. Carcinosarcoma of the submandibular salivary gland. Eur J Surg Oncol. 1999;25:333-335.
25. Wick MR, Swanson PE. Carcinosarcomas: current perspectives and an historical review of nosological concepts. Semin Diagn Pathol. 1993;10:118-127.
26. McCluggage WG. Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas? J Clin Pathol. 2002;55:321-325.
27. Thompson L, Chang B, Barsky SH. Monoclonal origins of malignant mixed tumors (carcinosarcomas): evidence for a divergent histogenesis. Am J Surg Pathol. 1996;20:277-285.
28. Szukala SA, Marks JR, Burchette JL, et al. Co-expression of p53 by epithelial and stromal elements in carcinosarcoma of the female genital tract: an immunohistochemical study of 19 cases. Int J Gynecol Cancer. 1999;9:131-136.
29. Wang X, Mori I, Tang W, et al. Metaplastic carcinoma of the breast: p53 analysis identified the same point mutation in the three histologic components. Mod Pathol. 2001;14:1183-1186.
30. Dacic S, Finkelstein SD, Sasatomi E, et al. Molecular pathogenesis of pulmonary carcinosarcoma as determined by microdissection-based allelotyping. Am J Surg Pathol. 2002;26:510-516.
31. Seifert G, Donath K. Multiple tumours of the salivary glands: terminology and nomenclature. Eur J Cancer B Oral Oncol. 1996;32B:3-7.
32. Chhieng C, Cranor M, Lesser ME, et al. Metaplastic carcinoma of the breast with osteocartilaginous heterologous elements. Am J Surg Pathol. 1998;22:188-194.
33. Love GL, Sarma DP. Spindle cell mucoepidermoid carcinoma of submandibular gland. J Surg Oncol. 1986;31:66-68.
34. Ferreiro JA, Kochar AS. Parotid acinic cell carcinoma with undifferentiated spindle cell transformation. J Laryngol Otol. 1994;108:902-904.
35. Ishibashi T, Hojo H. Spindle cell carcinoma of the parotid gland. J Laryngol Otol. 1995;109:683-686.
36. Latkovich P, Johnson RL. Carcinosarcoma of the parotid gland: report of a case with cytohistologic and immunohistochemical findings. Arch Pathol Lab Med. 1998;122:743-746.
37. Manuel S, Mathews A, Chandramohan K, et al. Carcinosarcoma of the parotid gland with epithelial-myoepithelial carcinoma and pleomorphic sarcoma components. Br J Oral Maxillofac Surg. 2002;40:480-483.
38. Lugo M, Putong PB. Metaplasia: an overview. Arch Pathol Lab Med. 1984;108:185-189.
39. Foschini MP, Dina RE, Eusebi V. Sarcomatoid neoplasms of the breast: proposed definitions for biphasic and monophasic sarcomatoid mammary carcinomas. Semin Diagn Pathol. 1993;10:128-136.
40. Dunne B, Lee AH, Pinder SE, et al. An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast. Hum Pathol. 2003;34:1009-1015.
41. Wick MR, Ockner DM, Mills SE, et al. Homologous carcinomas of the breasts, skin, and salivary glands: a histologic and immunohistochemical comparison of ductal mammary carcinoma, ductal sweat gland carcinoma, and salivary duct carcinoma. Am J Clin Pathol. 1998;109:75-84.
42. Nasser SM, Faquin WC, Dayal Y. Expression of androgen, estrogen, and progesterone receptors in salivary gland tumors: frequent expression of androgen receptor in a subset of malignant salivary gland tumors. Am J Clin Pathol. 2003;119:801-806.
43. Nagao T, Sugano I, Ishida Y, et al. Hybrid carcinomas of the salivary glands: report of nine cases with a clinicopathologic, immunohistochemical, and p53 gene alteration analysis. Mod Pathol. 2002;15:724-733.
44. Nagao T, Sugano I, Ishida Y, et al. Salivary gland malignant myoepithelioma: a clinicopathologic and immunohistochemical study of ten cases. Cancer. 1998;83:1292-1299.