-
1
-
-
0037084298
-
Linezolid: Its role in the treatment of Gram-positive, drug-resistant bacterial infections
-
AMENT, P. W., JAMSHED, N. and HORNE, J. P., 2002, Linezolid: its role in the treatment of Gram-positive, drug-resistant bacterial infections. American Family Physician, 65, 663-670.
-
(2002)
American Family Physician
, vol.65
, pp. 663-670
-
-
Ament, P.W.1
Jamshed, N.2
Horne, J.P.3
-
2
-
-
0034812539
-
Animal pharmacokinetics and interspecies scaling of sordarin derivatives following intravenous administration
-
AVILES, P., PATEMAN, A., SAN ROMAN, R., GUILLEN, M. J., GOMEZ DE LASHERA, F. and GARGALLO-VIOLA, D., 2001, Animal pharmacokinetics and interspecies scaling of sordarin derivatives following intravenous administration. Antimicrobial Agents and Chemotherapy, 45, 2787-2792.
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, pp. 2787-2792
-
-
Aviles, P.1
Pateman, A.2
San Roman, R.3
Guillen, M.J.4
Gomez De Lashera, F.5
Gargallo-Viola, D.6
-
3
-
-
0035746813
-
Linezolid: Pharmacokinetic characteristics and clinical studies
-
BOUZA, E. and MUNOZ, P., 2001, Linezolid: pharmacokinetic characteristics and clinical studies. Clinical Microbial Infections, 7, 75-82.
-
(2001)
Clinical Microbial Infections
, vol.7
, pp. 75-82
-
-
Bouza, E.1
Munoz, P.2
-
4
-
-
0021703938
-
Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm
-
BOXENBAUM, H., 1984, Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm. Drug Metabolism Reviews, 15, 1071-1112.
-
(1984)
Drug Metabolism Reviews
, vol.15
, pp. 1071-1112
-
-
Boxenbaum, H.1
-
5
-
-
0042925335
-
Pharmacokinetics of linezolid in subjects with renal dysfunction
-
BRIER, M. E., STALKER, D. J., ARONOFF, G. R., BATTS, D. H., RYAN, K. K., O'GRADY, M., HOPKINS, N. K. and JUNGBLUTH, G. L., 2003, Pharmacokinetics of linezolid in subjects with renal dysfunction. Antimicrobial Agents and Chemotherapy, 47, 2775-2780.
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, pp. 2775-2780
-
-
Brier, M.E.1
Stalker, D.J.2
Aronoff, G.R.3
Batts, D.H.4
Ryan, K.K.5
O'Grady, M.6
Hopkins, N.K.7
Jungbluth, G.L.8
-
6
-
-
0035428023
-
The discovery of linezolid, the first oxazolidinone antibacterial agent
-
FORD, C. W., ZURENKO, G. E. and BARBACHYN, M. R., 2001, The discovery of linezolid, the first oxazolidinone antibacterial agent. Current Drug Targets in Infectious Disorders, 1, 181-199.
-
(2001)
Current Drug Targets in Infectious Disorders
, vol.1
, pp. 181-199
-
-
Ford, C.W.1
Zurenko, G.E.2
Barbachyn, M.R.3
-
7
-
-
0035031377
-
Linezolid: Pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanol-amine HCl, and dextromethorpan HBr
-
HENDERSHOT, P. E., ANTAL, E. J., WELSHMAN, I. R., BATTS, D. H. and HOPKINS, N. K., 2001, Linezolid: pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanol-amine HCl, and dextromethorpan HBr. Journal of Clinical Pharmacology, 41, 563-572.
-
(2001)
Journal of Clinical Pharmacology
, vol.41
, pp. 563-572
-
-
Hendershot, P.E.1
Antal, E.J.2
Welshman, I.R.3
Batts, D.H.4
Hopkins, N.K.5
-
8
-
-
0037525986
-
Pharmacokinetics, pharmacodynamics, allometry, and dose selection of rPSGL-Ig for phase I trial
-
KHOR, S. P., MCCARTHY, K., DU PONT, M., MURRAY, K. and TIMONY, G., 2000, Pharmacokinetics, pharmacodynamics, allometry, and dose selection of rPSGL-Ig for phase I trial. Journal of Pharmacology and Experimental Therapeutics, 293, 618-624.
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.293
, pp. 618-624
-
-
Khor, S.P.1
McCarthy, K.2
Du Pont, M.3
Murray, K.4
Timony, G.5
-
9
-
-
0038778571
-
Pharmacokinetic and pharmacodynamic profile of linezolid in healthy volunteers and patients with Gram-positive infections
-
MACGOWAN, A. P., 2003, Pharmacokinetic and pharmacodynamic profile of linezolid in healthy volunteers and patients with Gram-positive infections. Journal of Antimicrobial Chemotherapy, 51, 17-25.
-
(2003)
Journal of Antimicrobial Chemotherapy
, vol.51
, pp. 17-25
-
-
MacGowan, A.P.1
-
10
-
-
0035294104
-
Interspecies scaling of maximum tolerated dose of anticancer drugs: Relevance to starting dose for phase I clinical trials
-
MAHMOOD, I., 2001a, Interspecies scaling of maximum tolerated dose of anticancer drugs: relevance to starting dose for phase I clinical trials. American Journal of Therapeutics, 8, 109-116.
-
(2001)
American Journal of Therapeutics
, vol.8
, pp. 109-116
-
-
Mahmood, I.1
-
11
-
-
0035745798
-
Interspecies scaling: Is a priori knowledge of cytochrome p450 isozymes involved in drug metabolism helpful in prediction of clearance in humans from animal data
-
MAHMOOD, I., 2001b, Interspecies scaling: is a priori knowledge of cytochrome p450 isozymes involved in drug metabolism helpful in prediction of clearance in humans from animal data. Drug Metabolism and Drug Interaction, 18, 135-147.
-
(2001)
Drug Metabolism and Drug Interaction
, vol.18
, pp. 135-147
-
-
Mahmood, I.1
-
12
-
-
0036379076
-
Prediction of clearance in humans from in vitro human liver microsomes and allometric scaling. A comparative study of the two approaches
-
MAHMOOD, I., 2002, Prediction of clearance in humans from in vitro human liver microsomes and allometric scaling. A comparative study of the two approaches. Drug Metabolism and Drug Interaction, 19, 49-64.
-
(2002)
Drug Metabolism and Drug Interaction
, vol.19
, pp. 49-64
-
-
Mahmood, I.1
-
13
-
-
0037458217
-
Linezolid: The first oxazolidinone antimicrobial
-
MOELLERING, R. C., 2003, Linezolid: the first oxazolidinone antimicrobial. Annals of Internal Medicine, 138, 144.
-
(2003)
Annals of Internal Medicine
, vol.138
, pp. 144
-
-
Moellering, R.C.1
-
14
-
-
0035063748
-
Linezolid: A review of its use in the management of serious Gram-positive infections
-
PERRY, C. M. and JARVIS, B., 2001, Linezolid: a review of its use in the management of serious Gram-positive infections. Drugs, 61, 525-551.
-
(2001)
Drugs
, vol.61
, pp. 525-551
-
-
Perry, C.M.1
Jarvis, B.2
-
16
-
-
0041663524
-
Pharmacokinetic scaling of SJ-8029, a novel anticancer agent possessing microtubule and topoisomerase inhibiting activities, species-invariant time methods
-
SHIN, B. S., KIM, D. H., CHO, C. Y., PARK, S. K., CHUNG, S. G., CHO, E. H., LEE, S. H., JOO, J. H., KWON, H. S., LEE, K. C. and YOO, S. D., 2003, Pharmacokinetic scaling of SJ-8029, a novel anticancer agent possessing microtubule and topoisomerase inhibiting activities, species-invariant time methods. Biopharmaceutics and Drug Disposition, 24, 191-197.
-
(2003)
Biopharmaceutics and Drug Disposition
, vol.24
, pp. 191-197
-
-
Shin, B.S.1
Kim, D.H.2
Cho, C.Y.3
Park, S.K.4
Chung, S.G.5
Cho, E.H.6
Lee, S.H.7
Joo, J.H.8
Kwon, H.S.9
Lee, K.C.10
Yoo, S.D.11
-
17
-
-
0035712257
-
Age and sex effects on the pharmacokinetics of linezolid
-
SISSON, T. L., JUNGBLUTH, G. L. and HOPKINS, N. K., 2002, Age and sex effects on the pharmacokinetics of linezolid. European Journal of Clinical Pharmacology, 57, 793-797
-
(2002)
European Journal of Clinical Pharmacology
, vol.57
, pp. 793-797
-
-
Sisson, T.L.1
Jungbluth, G.L.2
Hopkins, N.K.3
-
18
-
-
18644367890
-
Pharmacokinetics, toxicokinetics, distribution, metabolism and excretion of linezolid in mouse, rat and dog
-
SLATTER, J. G., ADAMS, L. A, BUSH, E. C, CHIBA, K, DALEY-YATES, P. T., FEENSTRA, K. L., KOIKE, S., OZAWA, N., PENG, G. W., SAMS, J. P., SCHUETTE, M. R. and YAMAZAKI, S., 2002, Pharmacokinetics, toxicokinetics, distribution, metabolism and excretion of linezolid in mouse, rat and dog. Xenobiotica, 32, 907-924.
-
(2002)
Xenobiotica
, vol.32
, pp. 907-924
-
-
Slatter, J.G.1
Adams, L.A.2
Bush, E.C.3
Chiba, K.4
Daley-Yates, P.T.5
Feenstra, K.L.6
Koike, S.7
Ozawa, N.8
Peng, G.W.9
Sams, J.P.10
Schuette, M.R.11
Yamazaki, S.12
-
19
-
-
0034932457
-
14C] linezolid to healthy human subjects
-
14C] linezolid to healthy human subjects. Drug Metabolism and Disposition, 29, 1136-1145.
-
(2001)
Drug Metabolism and Disposition
, vol.29
, pp. 1136-1145
-
-
Slatter, J.G.1
Stalker, D.J.2
Feenstra, K.L.3
Welshman, I.R.4
Bruss, J.B.5
Sams, J.P.6
Johnson, M.G.7
Sanders, P.E.8
Hauer, M.J.9
Fagerness, P.E.10
Stryd, R.P.11
Peng, G.W.12
Shobe, E.M.13
-
20
-
-
0242320209
-
Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial
-
STALKER, D. and JUNGBLUTH, G., 2003, Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial. Clinical Pharmacokinetics, 42, 1129-1140.
-
(2003)
Clinical Pharmacokinetics
, vol.42
, pp. 1129-1140
-
-
Stalker, D.1
Jungbluth, G.2
-
21
-
-
0038440756
-
Pharmacokinetics and tolerance of single- and multiple-dose oral or intravenous linezolid, an oxazolidinone antibiotic, in healthy volunteers
-
STALKER, D. J., JUNGBLUTH, G. L., HOPKINS, N. K. and BATTS, D. H., 2003, Pharmacokinetics and tolerance of single- and multiple-dose oral or intravenous linezolid, an oxazolidinone antibiotic, in healthy volunteers. Journal of Antimicrobial and Chemotherapy, 51, 1239-1246.
-
(2003)
Journal of Antimicrobial and Chemotherapy
, vol.51
, pp. 1239-1246
-
-
Stalker, D.J.1
Jungbluth, G.L.2
Hopkins, N.K.3
Batts, D.H.4
-
22
-
-
0035678986
-
Pharmacokinetics and interspecies scaling of a novel VEGF receptor inhibitor, SU5416
-
SUKBUNTHERNG, J., CROPP, G., HANNAH, A., WAGNER, G. S., SHAWVER, L. K. and ANTONIAN, L., 2001, Pharmacokinetics and interspecies scaling of a novel VEGF receptor inhibitor, SU5416. Journal of Pharmacy and Pharmacology, 53, 1629-1636.
-
(2001)
Journal of Pharmacy and Pharmacology
, vol.53
, pp. 1629-1636
-
-
Sukbuntherng, J.1
Cropp, G.2
Hannah, A.3
Wagner, G.S.4
Shawver, L.K.5
Antonian, L.6
-
23
-
-
0036204914
-
SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. II: In vitro and in vivo metabolism studies and pharmacokinetic extrapolation to man
-
WARD, K. W., PROKSCH, J. W., GORYCKI, P. D., YU, C. P., HO, M. Y., BUSH, B. D., LEVY, M. and SMITH, B. R., 2002, SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. II: in vitro and in vivo metabolism studies and pharmacokinetic extrapolation to man. Xenobiotica, 32, 235-250.
-
(2002)
Xenobiotica
, vol.32
, pp. 235-250
-
-
Ward, K.W.1
Proksch, J.W.2
Gorycki, P.D.3
Yu, C.P.4
Ho, M.Y.5
Bush, B.D.6
Levy, M.7
Smith, B.R.8
-
24
-
-
0035660591
-
Linezolid absolute bioavailability and the effect of food on oral bioavailability
-
WELSHMAN, I. R., SISSON, T. A., JUNGBLUTH, G. L., STALKER, D. J. and HOPKINS, N. K., 2001, Linezolid absolute bioavailability and the effect of food on oral bioavailability. Biopharmaceutics and Drug Disposition, 22, 91-97.
-
(2001)
Biopharmaceutics and Drug Disposition
, vol.22
, pp. 91-97
-
-
Welshman, I.R.1
Sisson, T.A.2
Jungbluth, G.L.3
Stalker, D.J.4
Hopkins, N.K.5
-
25
-
-
0002724545
-
In vitro metabolism of linezolid (PNU-100766): Lack of induction or inhibition of cytochrome P450 enzymes and studies on the mechanism of formation of the major human metabolite, PNU-142586
-
San Francisco, CA
-
WIENKERS, L. C., WYNDALDA, M. A., FEENSTRA, K. L., GAO, P. and SLATER, J. G., 1999, In vitro metabolism of linezolid (PNU-100766): lack of induction or inhibition of cytochrome P450 enzymes and studies on the mechanism of formation of the major human metabolite, PNU-142586. In Proceedings of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, CA.
-
(1999)
Proceedings of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Wienkers, L.C.1
Wyndalda, M.A.2
Feenstra, K.L.3
Gao, P.4
Slater, J.G.5
-
26
-
-
0033831324
-
Oxidation of novel oxazolidinone antibiotic linezolid in human liver microsomes
-
WYNALDA, M. A., MICHAEL, J. H. and LARRY, C. W., 2000, Oxidation of novel oxazolidinone antibiotic linezolid in human liver microsomes. Drug Metabolism Disposition, 20, 1014-1017.
-
(2000)
Drug Metabolism Disposition
, vol.20
, pp. 1014-1017
-
-
Wynalda, M.A.1
Michael, J.H.2
Larry, C.W.3
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