Anti-inflammatory effects of erythromycin and tetracycline onPropionibacterium acnes induced production of chemotactic factors and reactiveoxygen species by human neutrophils

Dermatology Online Journal

Volumn 8, Issue 2, 2002, Pages 12-25

  Jain, A ^a   Sangal, L ^a   Basal, E ^a   Kaushal, G P ^a   Agarwal, S K ^a  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTACTIC FACTOR; CYTOCHROME C; ERYTHROMYCIN; REACTIVE OXYGEN METABOLITE; TETRACYCLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; GROWTH CURVE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PROPIONIBACTERIUM ACNES;

EID: 3242734848     PISSN: 10872108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Webster GF, Leyden JJ, Mechanisms of Propionibacterium acnes mediated inflammation in acne vulgaris, Semin Dermatol. 1: 299-304, 1982.
2. Puhvel S M, Sakamoto M, A re-evaluation of fatty acids as inflammatory agents in acne, J Invest Dermatol. 68: 93-99, 1977.
3. Strauss JS, Pochi PE, Intracutaneous injection of sebum and comedones, Arch Dermatol. 92: 443-456, 1965.
4. Freinkel RK, Strauss JS, Yip SY, Pochi PE, Effect of tetracycline on the composition of sebum in acne vulgaris, N Engl J Med. 273: 850-854, 1965.
5. Puhvel SM, Sakamoto M, The chemoattractant properties of comedonal contents, J Invest Dermatol. 71: 324-329, 1978.
6. Webster G F, Leyden J J, Tsai CC, Bachni P, McArthur WP, Polymorphonuclear leukocyte Lysosomal release in response to Propionibacterium acnes in vitro and its enhancement by sera from patients with inflammatory acne, J Invest Dermatol. 74: 399-401, 1980.
7. Webster GF, Kligman AM, A method for the assay of inflammatory mediators in follicular casts, J Invest Dermatol. 73: 266-268, 1979.
8. Martin RR, Warr JA, Couch RB, Yeager H, Knight V, Effects of tetracycline on leukotaxis, J Infect Dis. 129: 110-115, 1974.
9. Reebuck J W, Crowley J H, A method of studying leukocyte function in vivo, Ann. N.Y. Acad. Science. 59: 757, 1955.
10. Park B H, Fikrig S M, Smithwick E M, Infection and nitroblue tetrazolium reduction by neutrophils, Lancet. 532, 1968.
11. Boyum A, Isolation of mononuclear cells and granulocytes from human blood, Scand. J. Clin. Lab. Invest. 21(Suppl-97): 77-89, 1968.
12. Weening R S, Wever R, Ross D, Quantitative aspects of the production of superoxide radical by phagocytosing human granulocytes, J. Lab. Clin. Med. 85: 245, 1975.
13. Zar J H, Biostatistical Analysis, Prentice. 1974.
14. Holland K T, Ingham E, Cunileffe W J, A review-The microbiology of acne, Journal of Applied Bacteriology. 51: 195, 1981.
15. Massey A, Mowbray J F, Noble W C, Complement activation of Corynebacterium acnes, Br. J.Dermatol. 98: 583-584, 1978.
16. Russel R J, McInroy R J, Wilkinson P C, White R G, A lipid chaemotactic factor from an aerobic coryneform bacteria including Corynebacterium parvum, with activity for macrophages and monocytes, Immunology. 30: 935, 1976.
17. Gould D J, Cunileffe W J, Holland K T, Chemotaxis and acne, J Invest. Dermatol. 68: 251, 1977.
18. Lee W L, Suntharalingam K, Fiking S M, Shalita A R, Neutrophil chemotaxis by P. acnes, Clin. Res. 25, 283A, 1977.
19. Akamatsu H, Horio T, The possible Role of reactive oxygen species generated by neutrophils in mediating Acne Inflammation, Dermatology. 196: 82-85, 1998.
20. Webster G F, Leyden J J, McGinley K J, and McArthur W P, Suppression of polymorphonuclear leukocyte chemotactic factor production in Propionibacterium acnes by subminimal inhibitory concentrations of Tetracycline, Ampicillin, Minocycline, and Erythromycin, Antimicrobial Agents & Chemotherapy. 21: 770-772, 1982.
21. Akamatsu H, Kurokawa I, Nishijima S, and Asada Y, Inhibition of neutrophil chemotactic factor production in comedonal bacteria by subminimal inhibitory concentrations of Erythromycin, Dermatology. 185: 41-43, 1992.
22. Elewsky B E, Sam M Jr, Gammon W R, In Vivo suppression of neutrophil chemotaxis by systemically and topically administered tetracycline, J Am Acad Dermatol. 8: 807-812, 1983.
23. Webster G F, Leyden J J, Production of serum independent polymorphonuclear leukocyte chemotactic factors by Propionibacterium acnes, Inflammation. 4: 261-269, 1980.
24. Miyachi Y, Yoshioka A, Imammura S, Niwa Y, Effect of antibiotics on the generation of reactive oxygen species, J. Invest. Dermatol. 86: 449-453, 1986.
25. Akamatsu H, Nishijima S, Takahashi M, Ushijima H, Asada Y, Oguchi M, Niwa Y, The inhibition of free radical generation by human neutrophils through the synergistic effect of metronidazole with palmitoleic acid; possible mechanism of action of metronidazole in rosacea and acne, Dermatol Res. 282: 449-454, 1990.
26. Oguchi M, Akamatsu H, Asada M, et al., Treatment of acne with oral metronidazole, Skin Res. 28: 995-1000, 1987.
27. Pye R J, Burton J L, Treatment of rosacaa by metronidazole, Lancet. 1211-1215, 1976.