The importance of cyclin D1 and Ki67 expression on the biological behavior of pancreatic adenocarcinomas

Pathology Research and Practice

Volumn 200, Issue 5, 2004, Pages 389-396

  Lebe, Banu ^a   Saǧol, Özgül ^a   Ulukuş, Çaǧnur ^a   Çoker, Ahmet ^a   Karademir, Sedat ^a   Astarcloglu, Hüseyin ^a   Küpelioǧlu, Ali ^a   Astarcloǧlu, Ibrahim ^a   Obuz, Funda ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Cyclin D1; Ki67; Pancreatic carcinoma; Prognosis

Indexed keywords

BIOTIN; CELL CYCLE PROTEIN; CYCLIN D1; FORMALDEHYDE; KI 67 ANTIGEN; PARAFFIN; STREPTAVIDIN;

ADULT; AGED; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ARTICLE; CANCER INVASION; CANCER STAGING; CANCER SURVIVAL; CLINICAL STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; LYMPHANGIOMA; MAJOR CLINICAL STUDY; MALE; PANCREAS ADENOCARCINOMA; PERINEURIUM; PROGNOSIS; QUANTITATIVE ANALYSIS; STANDARD; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 3242718951     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prp.2004.02.010     Document Type: Article

References (34)

1. Allema J.H. Reinders M.E. Van Gulik T.M. Koelemay M.J. Van Leeuwen D.E. Wit L.T. Gouma D.J. Obertop H. Prognostic factors for survival after pancreaticoduodenectomy for patients with carcinoma of the pancreatic head region Cancer 75 1995 2069-2076
2. Allison D.C. Piantadosi S. Hruban R.H. Dooley W.C. Fishman E.K. Yeo C.J. Lillemoe K.D. Pitt H.A. Lin P. Cameron J.L. DNA content and the other factors associated with ten-year survival after resection of pancreatic carcinoma J. Surg. Oncol. 67 1998 151-159
3. Arber N. Gammon M.D. Hibshoosh H. Britton J.A. Zhang Y. Schonberg J.B. Roterdam H. Fabian I. Holt P.R. Weinstein B. Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach Hum. Pathol. 30 1999 1087-1092
4. Biankin A.V. Kench J.G. Morey A.L. Lee C.S. Biankin S.A. Head D.R. Hugh T.B. Henshall S.M. Sutherland R.L. Overexpression of p21WAFl/CIPl is an early enevt in the development of pancreatic intraepithelial neoplasia Cancer Res. 61 2001 8830-8837
5. Bold R.J. Hess K.R. Pearson A.S. Grau A.M. Sinicrope F.A. Jennings M. McConkey D.J. Bucana C.D. Cleary K.R. Hallin H.A. Chiao P.J. Abbruzzese J.L. Evans D.B. Prognostic factors in resectable pancreatic cancer J Gastrointest. Surg. 3 1999 263-277
6. De Manzoni G. Verlato G. Tomezzoli A. Study on Ki-67 immunoreactivity as a prognostic indicator in patients with advanced gastric ancer Jpn. J. Clin. Oncol. 28 1998 534-537
7. Gansauge S. Gansauge F. Ramadani M. Stobbe H. Rau B. Harada N. Beger H.G. Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis Cancer Res. 57 1997 1634-1637
8. Gebhardt C. Meyer W. Reichel M. Wunsch P.H. Prognostic factors in the operative treatment of ductal pancreatic adenocarcinoma Langenbecks Arch. Surg. 385 2000 14-20
9. P. Hermanek, R.V.P. Hutter, L.H. Sobin, G. Wagner, C.H. Wittekint, Pancreas. In: TNM Atlas, 4th edition, Springer, Berlin, 1997, pp 144-152.
10. Holland T.A. Elder J. McCloud J.M. Hall C. Deakin M. Fryer A.A. Elder J.A. Hoban P.R. Subcellular localisation of cyclin D1 protein in colorectal tumors is associated with p21 WAF1/CIP1 expression and correlates with patient survival Int. J. Cancer 95 2001 302-306
11. Jiang W. Kahn S.M. Tomita N. et al. Amplification and expression of the human cyclin D gene in esophageal cancer Cancer 52 1992 2980-2983
12. Kawesha A. Ghaneh P. Andren-Sandberg A. Ögraed D. Skar R. Dawiskiba S. Evans J.D. Campbell F. Lemoine N. Neoptolemos J.P. K-ras onogene subtype mutations are associated with survival but not expression pf p53, p16INK4A, p21WAFl, cyclin D1 erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma Int. J. Cancer 89 2000 469-474
13. Kayahara M. Nagakawa T. Futagami F. Kitagawa H. Ohta T. Miyazaki I. Lymphatic flow and neural plexus invasion associated with carcinoma of the body and tail of the pancreas Cancer 15 1996 2485-2491
14. Keyomarsi K. Pardee A.B. Redundant cyclin overexpression and gene amplification in breast cancer cells Proc. Natl. Acad. Sci. USA 90 1993 1112-1116
15. Klöppel G. Lüttges J. WHO classification 2000: exocrine pancreatic tumors international histological of tumours Verh. Dtsch. Ges. Path. 85 2001 219-228
16. Lew D.J. Dulic V. Reed S.I. Isolation of three novel human cyclins by rescue of G1 cyclin function in yeast Cell 66 1991 1197-1206
17. Lüttges J. Schemm S. Vogel I. Hedderich J. Kremer B. Kloppel G. The grade of pancreatic ductal carcinoma is an independent prognostic factor and is superior to the immunohistochemical assessement of proliferation J. Pathol. 191 2000 154-161
18. Madea K. Chung Y.S. Kang S.M. Ogawa M. Onoda N. Nishiguchi Y. Ikehara T. Nakata B. Okuno M. Sowa M. Cyclin D1 overexpression and prognosis in colorectal adenocarcinoma Oncology 55 1998 145-151
19. Magistrelli P. Antinori A. Crucitti A. La Grece A. Masetti R. Coppola R. Nuzzo G. Picciocchi A. Prognostic factors after surgical resection for pancreatic carcinoma J. Surg. Oncol. 74 2000 36-40
20. Mclntosh G.G. Anderson J.J. Milton I. Steward M. Parr A.H. Thomas M.D. Henry J.A. Angus B. Lennard T.W.J. Horne C.H.W. Determination of the prognostic value of cyclin D1 expression in breast cancer Oncogene 11 1995 885-891
21. Meyer W. Jurowich C. Reichel M. Steinhauser B. Wunsch P.H. Gebhardt C. Pathomorphological and histological prognostic factors in curatively resected ductal adenocarcinoma of pancreas Surg. Today 30 2000 582-587
22. Naitoh H. Shibata J. Kawaguchi A. Kodama M. Hattori T. Overexpression and localisation of cyclin D1 mRNA and antigen in esophageal cancer Am. J. Pathol. 146 1995 1161-1169
23. Pines J. Hunter T. Cyclins and cancer II: Cyclin D1 and CDK inhibitors comes of age Cell 79 1994 573-582
24. Poch B. Gansauge F. Schwarz A. Seufferlein T. Schnelldorfer T. Ramadani M. Berger H.G. Gansauge S. Epidermal growth factor induces cyclin D1 is in human pancreatic carcinoma: evidence for a cyclin D1-dependent cell cycle progression Pancreas 23 2001 280-287
25. Rosenberg C.L. Kim H.G. Shows T.B. Kronenberg H.M. Arnold A. Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors Oncogene 6 1991 449-453
26. Sagol Ö. Kurtoǧlu B. Özer E. Pabuççuoǧlu U. Stereological estimation of mean nuclear volume and staining pattern of Ki67 antigen in keratoacanthomas and squamous cell carcinomas Gen. Diagn. Pathol. 143 1997/1998 305-309
27. Sagol Ö. Tuna B. Çoker A. Karademir S. Obuz F. Astarcioǧlu H. Küpelioǧlu A. Astarcioǧlu I. Topalak Ö. Immunohistochemical detection of pS2 protein and heat shock protein-70 in pancreatic adenocarcinomas Relationship with disease extant patient survival Pathol. Res. Pract. 198 2002 77-84
28. Sherr C.J. Mammalian Gl cyclins Cell 73 1993 1059-1065
29. Sherr C.J. Gl phase progression: cycling on cue Cell 79 1994 551-555
30. Sherr C.J. Cancer cell cycles Science 274 1996 1672-1677
31. Terada T. Ohta T. Kitamura Y. Ashida K. Matsunaga Y. Cell proliferative activity in intraductal papillary-mucinous neoplasms and invasive ductal adenocarcinomas of the pancreas: an immunohistochemical study Arch. Pathol. Lab. Med. 122 1998 42-46
32. Tut V.M. Braithwaite K.L. Angus B. Neal D.E. Lunec J. Mellon J.K. Cyclin D1 expression in transitional cell carcinoma of the bladder: correlation with p53 wafl pRb and Ki67 Br. J. Cancer 84 2001 270-275
33. Xiong Y. Connoly T. Futcher B. et al. Human D-type cyclin, Cell 65 1991 691-699
34. Zhang Y.J. Jiang W. Chen C.J. et al. Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma Biochem. Biopsy. Res. Commun. 196 1993 1010-1016