Activation of HHV-6 in lymphoproliferative disorders: A polymerase chain reaction-based study

Annals of the New York Academy of Sciences

Volumn 1022, Issue , 2004, Pages 282-285

  Tailor, P B ^a,b   Saikia, T K ^a   Advani, S H ^a   Mukhopadhyaya, R ^a  

^a TATA MEMORIAL HOSPITAL   (India)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

HHV 6 activation; Hodgkin's disease; Non Hodgkin's lymphoma; Plasma HHV 6 DNA

Indexed keywords

VIRUS DNA;

CANCER DIAGNOSIS; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; HERPES VIRUS INFECTION; HODGKIN DISEASE; HUMAN; HUMAN HERPESVIRUS 6; LYMPHOPROLIFERATIVE DISEASE; MAJOR CLINICAL STUDY; NONHODGKIN LYMPHOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; VIRUS ACTIVATION;

DNA VIRUSES; HERPESVIRIDAE; HUMAN HERPESVIRUS 6;

EID: 3242717533     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1318.043     Document Type: Conference Paper

References (17)

1. YAMANISHI, K., T. OKUNO, et al. 1988. Identification of human herpesvirus-6 as a causal agent for exanthum subitum. Lancet i: 1065-1067.
2. LUSSO, P. 1996. Human herpesvirus 6 (HHV-6). Antiviral Res. 31: 1-21.
3. SECCHIERO, P., D. CARRIGAN, et al. 1995. Detection of HHV-6 in plasma of children with primary infection and immunosuppressed patients by PCR. J. Infect. Dis. 171: 273-280.
4. JOSHI, P.J., R.H. MERCHANT, et al. 2000. Perinatally co-transmitted Human Herpes-virus 6 is activated in children born with Human Immunodeficiency Virus Infection. J. Human Virol. 3: 317-323.
5. NITSCHE, A., C.W. MULLER, et al. 2001. Human herpesvirus 6A DNA is detected frequently in plasma but rarely in peripheral blood leukocytes of patients after bone marrow transplantation. J. Infect. Dis. 183: 130-133.
6. TANNOCK, I.F. 1987. Immunotherapy and potential applications of monoclonal antibodies. In: Basic Biology of Cancer. I.F. Tannock & R.P. Hill, Eds.: 326-336. Pergamon Press. New York.
7. MUKHOPADHYAYA, R., S.H. ADVANI, et al. 1987. Functional evaluation of T-lymphocytes from peripheral blood and spleens in Hodgkin's disease. Brit. J. Can. 56: 800-802.
8. WANG, F., H. DAHL, et al. 1996. Lymphotrophic herpesviruses in allogenic bone marrow transplantation. Blood 88: 3615-3620.
9. SAIKI, R.K. 1990. Amplification of genomic DNA. In PCR Protocols: A Guide to Methods and Applications. M.A. Innis, D.H. Gelfand, J.J. Sninsky and T.J. White, Eds.: 21-27. Academic Press. San Diego, CA.
10. KWOK, S. & R. HIGUCHI. 1989. Avoiding false positives with PCR. Nature 339: 237.
11. KELLEY, P. & K. MCCLAIN. 1994. Respiratory contamination of polymerase chain reactions by human herpesvirus 6. Am. J. Hematol. 47: 325-327.
12. SALAHUDDIN, S., D.V. ABLASHI, et al. 1986. Isolation of new virus, HBLV, in patients with lymphoproliferative disorders. Science 234: 596-601.
13. BRAUN, D.K., G. DOMINGUEZ, et al. 1997. Human herpesvirus 6. Clin. Microbiol. Rev. 10: 521-567.
14. DOCKRELL, D.H., J. PRADA, et al. 1997. Seroconversion to human herpesvirus 6 following liver transplantation is a marker of cytomegalovirus disease. J. Infect. Dis. 176: 1135-1140.
15. OSMAN, H.K., J.S. PEIRIS, et al. 1997. Correlation between the detection of viral DNA by the polymerase chain reaction in peripheral blood leukocytes and serological responses to human herpesvirus 6, human herpesvirus 7, and cytomegalovirus in renal allograft recipients. J. Med. Virol. 53: 288-294.
16. HUANG, L., P. KUO, et al. 1992. Detection of Human herpesvirus 6 DNA by polymerase chain reaction in serum or plasma. J. Med. Virol. 38: 7-10.
17. SOLDAN, S.S., R. BERTI, et al. 1997. Association of human herpesvirus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6. Nat. Med. 3: 1394-1397.