An experimental method for measuring the mean length of cerebellar parallel fibers: Validation and derivation of a correction factor by computational simulation and probability analysis

Brain Research Bulletin

Volumn 64, Issue 1, 2004, Pages 15-24

  Huang, Rosa H ^a   Huang, Chi Ming ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Cerebellum; Granule cell axons; Mean length; Stochastic method

Indexed keywords

ARTICLE; BRAIN FUNCTION; CALCULATION; CEREBELLUM; EXPERIMENTATION; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; SAMPLING; SIMULATION; STOCHASTIC MODEL; VALIDATION PROCESS;

CEREBELLAR CORTEX; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; HUMANS; LIKELIHOOD FUNCTIONS; MODELS, NEUROLOGICAL; NERVE FIBERS; PROBABILITY; REPRODUCIBILITY OF RESULTS; STOCHASTIC PROCESSES;

EID: 3242714938     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2004.04.013     Document Type: Article

References (23)

1. Brand S., Dahl A.L., Mugnaini E. The length of parallel fibers in the cat cerebellar cortex: an experimental light and electron microscopic study. Exp. Brain Res. 26:1976;39-58
2. Eccles J.C., Llinas R., Sasaki K. Parallel fibre stimulation and the responses induced thereby in the Purkinje cells of the cerebellum. Exp. Brain Res. 1:1967;17-39
3. Gott J.R. Implications of the Copernican principle for our future prospects. Nature. 363:1993;315-319
4. Harvey R.J., Napper R.M.A. Quantitative studies of the mammalian cerebellum. Prog. Neurobiol. 36:1991;437-463
5. Huang C., Huang R. Measuring the mean length of parallel fibers in the rat cerebellum. Brain Res. 801:1998;211-215
6. Huang C., Brown N., Huang R. Age-related changes in the cerebellum: parallel fibers. Brain Res. 840:1999;148-152
7. M. Ito, The Cerebellum and Neural Control, Raven Press, New York, 1984.
8. Ito M. The cellular basis of cerebellar plasticity. Curr. Opin. Neurobiol. 1:1991;616-620
9. Lauder J.M. Effects of early hypo- and hyper-thyroidism on development of rat cerebellar cortex: IV the parallel fibers. Brain Res. 142:1978;25-39
10. Miyamoto H., Orpin S., Huang R., Huang C. Age-related changes in the mouse cerebellum. Neuroscience. 25:1999;29. (abstract)
11. H. Motulsky, Intuitive Biostatistics, Oxford University Press, Oxford, 1995.
12. Mugnaini E. The length of cerebellar parallel fibers in chicken and rhesus monkey. J. Comp. Neurol. 220:1983;7-15
13. Napper R.M.A., Harvey R.J. Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat. J. Comp. Neurol. 274:1988;168-177
14. S.L. Palay, V. Chan-Palay, The Cerebellar Cortex: Cytology and Organization, Springer-Verlag, New York, 1974.
15. Palkovitz M., Magyar P., Szentagothai J. Quantitative histological analysis of the cerebellar cortex in the cat. II. Cell numbers and densities in the granular layer. Brain Res. 32:1971;15-30
16. Palkovitz M., Magyar P., Szentagothai J. Quantitative histological analysis of the cerebellar cortex in the cat. III. Structural organization of the molecular layer. Brain Res. 34:1971;1-18
17. Pichitpornchai C., Rawson J.A., Rees S. Morphology of parallel fibers in the cerebellar cortex of the rat: an experimental light and electron microscopic study with biocytin. J. Comp. Neurol. 342:1994;206-220
18. M.E. Scheibel, A.B. Scheibel, The method of Golgi, in: R.T. Robertson (Ed.), Neuroanatomical Research Techniques, Academic Press, New York, 1978, pp. 89-114.
19. Schild R. Length of the parallel fibres in rat cerebellar cortex. J. Physiol. 303:1980;25P
20. Shambes G.M., Gibson J.M., Welker W. Fractured somatotopy in granule cell tactile areas of rat cerebellar hemispheres revealed by micromapping. Brain Behav. Evol. 15:1978;94-120
21. Shepherd G.M.G., Raastad M., Andersen P. General and variable features of varicosity spacing along unmyelinated axons in the hippocampus and cerebellum. Proc. Natl. Acad. Sci. U.S.A. 99:2002;6340-6345
22. Shepherd G.M.G., Raastad M. Axonal varicosity distributions along parallel fibers: a new angle on a cerebellar circuit. The Cerebellum. 2:2003;110-113
23. Wang L., Huang R., Huang C. Differential synaptic loss in aging cerebellar granule cells. Neuroscience. 26:2000;534. (abstract)