Chromosomal transformation in donor cells following allogeneic bone marrow transplantation

Bone Marrow Transplantation

Volumn 33, Issue 12, 2004, Pages 1253-1256

  Lang, Z ^a,b,c   Dinndorf, P ^a,b,c   Ladisch, S ^a,b,c   Bayever, E ^a,b,c   Reaman, G ^a,b,c  

^a Center for Cancer and Blood Disorders   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Donor cell transformation; Microsatellite analysis

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; CYTARABINE; THYMOCYTE ANTIBODY;

ALLOGENIC BONE MARROW TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; CASE REPORT; CELL DIFFERENTIATION; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CYTOGENETICS; DISEASE SEVERITY; FEMALE; GENETIC TRANSFORMATION; HLA MATCHING; HUMAN; LIVING DONOR; MICROENVIRONMENT; MICROSATELLITE MARKER; MONOSOMY 7; NEWBORN; PATIENT MONITORING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECIPIENT; WHOLE BODY RADIATION;

ANEMIA, APLASTIC; BONE MARROW TRANSPLANTATION; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES, HUMAN, PAIR 7; CYTOGENETIC ANALYSIS; FEMALE; HUMANS; INFANT; MONOSOMY; POLYMERASE CHAIN REACTION; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 3242705128     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704450     Document Type: Article

References (18)

1. Witherspoon RP, Deeg HJ, Storb R. Secondary malignancies after marrow transplantation for leukemia or aplastic anemia. Transplant Sci 1994; 4: 33-41.
2. Lawler SD, Baker MC, Harris H et al. Cytogenetic studies on recipients of allogeneic bone marrow using the sex chromosomes as markers of cellular origin. Br J Haematol 1984; 56: 431-443.
3. Zaccaria A, Alimena G, Baccarani M et al. Cytogenetic analyses in 89 patients with secondary hematologic disorders - results of a cooperative study. Cancer Genet Cytogenet 1987; 26: 65-74.
4. Boyd CN, Ramberg RC, Thomas ED. The incidence of recurrence of leukemia in donor cells after allogeneic bone marrow transplantation. Leuk Res 1982; 6: 833-837.
5. Bayever E, Ladisch S, Phillippart M et al. Bone-marrow transplantation for metachromatic leucodystrophy. Lancet 1985; 2: 471-473.
6. Stein J, Zimmerman PA, Kochera M et al. Origin of leukemic relapse after bone marrow transplantation: comparison of cytogenetic and molecular analyses. Blood 1989; 73: 2033-2040.
7. Gob K, Klemperer MR. In vivo leukemic transformation: cytogenetic evidence of in vivo leukemic transformation of engrafted marrow cells. Am J Hematol 1977; 2: 283-290.
8. Scharf SJ, Smith AG, Hansen JA et al. Quantitative determination of bone marrow transplant engraftment using fluorescent polymerase chain reaction primers for human identity markers. Blood 1995; 85: 1954-1963.
9. Takahashi R, Shimazaki C, Inaba T et al. Donor cell-derived acute myeloid leukemia developed shortly after allogeneic bone marrow transplantation for MDS overt leukemia. Rinsho Ketsueki 2002; 43: 963-965.
10. Cooley LD, Sears DA, Udden MM et al. Donor cell leukemia: report of a case occurring 11 years after allogeneic bone marrow transplantation and review of the literature. Am J Hematol 2000; 63: 46-53.
11. McCann SR, Lawler M, Gardener N et al. Donor leukemia following allogeneic bone marrow transplantation. Leukemia 1994; 8: S133-S135.
12. Lawler M, Humphries P, McCann SR. Evaluation of mixed chimerism by in vitro amplification of dinucleotide repeat sequences using the polymerase chain reaction. Blood 1991; 77: 2504-2514.
13. Browne PV, Lawler M, Humphries P et al. Donor-cell leukemia after bone marrow transplantation for severe aplastic anemia. N Engl J Med 1991; 325: 710-713.
14. Bayever E, Haines K, Duprey S et al. Protection of uninfected human bone marrow cells in long-term culture from G418 toxicity after retroviral-mediated transfer of the NEOr gene. Exp Cell Res 1988; 179: 168-180.
15. Santucci MA, Trabetti E, Martinelli G et al. Host origin of bone marrow fibroblasts following allogeneic bone marrow transplantation for chronic myeloid leukemia. Bone Marrow Transplant 1992; 10: 255-259.
16. Lawler M. Leukaemogenesis, gene interplay, and the role of the haemopoietic environment. Radiat Oncol Investig 1997; 5: 154-157.
17. McCann SR, Lawler M, Bacigalupo A. Recurrence of Philadelphia chromosome-positive leukemia in donor cells after bone marrow transplantation for chronic granulocytic leukemia. Leuk Lymphoma 1993; 10: 419-425.
18. Hashino S, Imamura M, Tanaka J et al. Transformation of severe aplastic anemia in acute myeloblastic leukemia with monosomy 7. Ann Hematol 1996; 72: 337-339.